Retinoblastoma — Variants & evidence

Retinoblastoma — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

3 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–3 of 3 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CDKN1A rs10592341
(predisposing)	Predisposing	B	Supports Predisposition	3	accepted	EID9244 This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found that RB1 carriers were more likely to have t… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC	civic
CDKN1A rs18012701
(predisposing)	Predisposing	B	Supports Predisposition	3	accepted	EID7227 This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found that RB1 carriers were more likely to have t… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC	civic
CDKN1A rs1801270 and rs10592341
(predisposing)	Predisposing	B	Supports Predisposition	3	submitted	EID9245 This study examined two CDKN1A polymorphisms (rs1801270 and rs1059234) in 141 carriers of RB1 variants and 120 unrelated healthy individuals. Authors found the chance of developing retinoblastoma incr… (full text at CIViC) PMID 24045412 · Carvalho et al., 2013 · Open in CIViC	civic

Data updated 23 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.