Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03391843 | Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer | active not recruiting | Phase 2 | 100 | RenJi HospitalOTHER | 1 | Jan 5, 2018 | clinicaltrials |
| NCT02942563 | Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | unknown | Phase 2 | 100 | RenJi HospitalOTHER | 1 | Jan 3, 2018 | clinicaltrials |
| NCT00226941 |
| A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer |
| terminated |
| Phase 1 / Phase 2 |
| 23 |
| George Albert FisherOTHER |
| 1 |
| Dec 8, 2017 |
| clinicaltrials |
| NCT02473094 | Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer(NEOMETRE) | terminated | Phase 2 | 3 | University of Campinas, BrazilOTHER | 1 | Nov 28, 2017 | clinicaltrials |
| NCT00972881 | Capecitabine, Irinotecan Hydrochloride, Cetuximab, and Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer(EXCITE) | completed | Phase 1 / Phase 2 | 82 | University College, LondonOTHER | 1 | Oct 25, 2017 | clinicaltrials |
| NCT01431599 | Short-course Preoperative Chemoradiotherapy for Rectal Cancer(KROG 11-02) | unknown | Phase 2 | 80 | Jong Hoon LeeOTHER | 1 | Oct 10, 2017 | clinicaltrials |
| NCT00682786 | Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma | completed | Phase 2 | 135 | Washington University School of MedicineOTHER | 1 | Oct 6, 2017 | clinicaltrials |
| NCT03280407 | NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer(NEOLAR) | unknown | Phase 2 | 124 | Zealand University HospitalOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT01952951 | Preoperative Chemoradiation Followed by Chemotherapy for Locally Advanced Rectal Cancer(PREPARE) | unknown | Phase 2 | 110 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 13, 2017 | clinicaltrials |
| NCT00847119 | Xeloda and Bevacizumab to Treat Rectal Cancer(xeberecto) | completed | Phase 2 | 43 | Institut Català d'OncologiaOTHER | 1 | Aug 29, 2017 | clinicaltrials |
| NCT01333709 | Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma(GRECCAR4) | completed | Phase 2 | 150 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Aug 21, 2017 | clinicaltrials |
| NCT01716949 | Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer(HyRec) | unknown | Phase 1 / Phase 2 | 59 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT00865189 | A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal Cancer(INOVA) | completed | Phase 2 | 91 | Hoffmann-La RocheINDUSTRY | 1 | Aug 4, 2017 | clinicaltrials |
| NCT01013805 | Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer(PROArCT) | completed | Phase 2 | 41 | Trans Tasman Radiation Oncology GroupOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT00468910 | Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer | completed | Phase 2 | 79 | National Cancer Institute (NCI)NIH | 1 | May 31, 2017 | clinicaltrials |
| NCT00307736 | Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer | completed | Phase 1 / Phase 2 | 32 | Massachusetts General HospitalOTHER | 1 | May 10, 2017 | clinicaltrials |
| NCT01273051 | Transanal Endoscopic Microsurgery (TEM) After Radiochemotherapy for Rectal Cancer(CARTS) | completed | Phase 2 | 55 | Radboud University Medical CenterOTHER | 1 | Apr 14, 2017 | clinicaltrials |
| NCT01270438 | Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Apr 4, 2017 | clinicaltrials |
| NCT01060007 | Five Fractions of Radiotherapy Followed by Full Dose FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer | completed | Phase 2 | 80 | Washington University School of MedicineOTHER | 1 | Mar 8, 2017 | clinicaltrials |
| NCT02526134 | Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum(FIDUCOR) | completed | Phase 2 | 29 | Institut Paoli-CalmettesOTHER | 1 | Mar 3, 2017 | clinicaltrials |
| NCT00335504 | Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia | completed | Phase 2 | 85 | National Cancer Institute (NCI)NIH | 1 | Feb 15, 2017 | clinicaltrials |
| NCT01749956 | 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer | completed | Phase 2 | 39 | SCRI Development Innovations, LLCOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT02046538 | Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer | withdrawn | Phase 2 | 0 | Weill Medical College of Cornell UniversityOTHER | 1 | Jan 25, 2017 | clinicaltrials |
| NCT02586610 | Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer | withdrawn | Phase 2 | 0 | Osama Rahma, MDOTHER | 0 | Jan 20, 2017 | clinicaltrials |
| NCT01507103 | Tecemotide (L-BLP25) in Rectal Cancer(SPRINT) | completed | Phase 2 | 124 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jan 13, 2017 | clinicaltrials |
| NCT02694718 | A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer | completed | Phase 2 | 60 | Hoffmann-La RocheINDUSTRY | 1 | Jan 11, 2017 | clinicaltrials |
| NCT02236884 | The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer | completed | Phase 1 / Phase 2 | 20 | Sun Yat-sen UniversityOTHER | 1 | Dec 19, 2016 | clinicaltrials |
| NCT00527111 | Pre-op Rectal ChemoRad +/- Cetuximab | completed | Phase 2 | 139 | US Oncology ResearchINDUSTRY | 1 | Nov 3, 2016 | clinicaltrials |
| NCT02941562 | A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT | unknown | Phase 2 | 150 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Oct 24, 2016 | clinicaltrials |
| NCT01043484 | Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer(AVAXEL) | completed | Phase 2 | 90 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 19, 2016 | clinicaltrials |
| NCT02287727 | Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment | withdrawn | Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | Oct 12, 2016 | clinicaltrials |
| NCT00278694 | Oxaliplatin and 5-FU Based Preoperative Chemoradiation(LARC-RRP) | completed | Phase 2 | 109 | Oslo University HospitalOTHER | 1 | Sep 29, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT01269229 | A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis | completed | Phase 2 | 32 | Yonsei UniversityOTHER | 1 | Sep 7, 2016 | clinicaltrials |
| NCT01320683 | Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer | terminated | Phase 2 | 1 | City of Hope Medical CenterOTHER | 1 | Jul 19, 2016 | clinicaltrials |
| NCT02830633 | Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer | unknown | Phase 2 | 80 | Anhui Medical UniversityOTHER | 0 | Jul 13, 2016 | clinicaltrials |
| NCT00336856 | Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy | completed | Phase 2 | 35 | University of PittsburghOTHER | 1 | Jul 12, 2016 | clinicaltrials |
| NCT01111292 | Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jul 12, 2016 | clinicaltrials |
| NCT02603302 | Radiation Dose Escalation in Locally Advanced Rectal Cancer(RaDE) | unknown | Phase 2 | 48 | University of BrasiliaOTHER | 1 | Jun 14, 2016 | clinicaltrials |
| NCT00216086 | Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer | terminated | Phase 2 | 22 | Gabi Chiorean, MDOTHER | 1 | Jun 6, 2016 | clinicaltrials |
| NCT02575508 | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | May 20, 2016 | clinicaltrials |
| NCT00931203 | Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer | completed | Phase 2 | 55 | National Health Research Institutes, TaiwanOTHER | 1 | May 4, 2016 | clinicaltrials |
| NCT00973193 | Preoperative Panitumumab and Radiotherapy in Rectal Cancer(PrePaRad) | terminated | Phase 2 | 20 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Apr 20, 2016 | clinicaltrials |
| NCT02745639 | Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer(GRACE) | completed | Phase 2 | 18 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 0 | Apr 20, 2016 | clinicaltrials |
| NCT02723253 | Concurrent Chemoradiation With Concomitant Boost In Locally Advanced Rectal Cancer | completed | Phase 2 | 18 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 0 | Mar 30, 2016 | clinicaltrials |
| NCT01821105 | 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer | completed | Phase 2 | 21 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 2, 2016 | clinicaltrials |
| NCT00587964 | Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases | completed | Phase 2 | 51 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 22, 2016 | clinicaltrials |
| NCT00411450 | Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment(PRECEPT) | completed | Phase 2 | 116 | AmgenINDUSTRY | 0 | Feb 15, 2016 | clinicaltrials |
| NCT01257360 | Panitumumab in Combination With Radiotherapy in Patients With Locally Advanced RAS Wildtype Rectal Cancer (Clinical Stages II and III)(NEO-RIT) | unknown | Phase 2 | 59 | WiSP Wissenschaftlicher Service Pharma GmbHOTHER | 1 | Jan 13, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Jan 5, 2018source: clinicaltrials