Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00353457 | Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma | terminated | Phase 2 | 6 | Abramson Cancer Center at Penn MedicineOTHER | 0 | Apr 9, 2020 | clinicaltrials |
| NCT01674309 | First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis | completed | Phase 2 | 65 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 30, 2020 |
| clinicaltrials |
| NCT02161822 | Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients | unknown | Phase 2 | 60 | Samsung Medical CenterOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT04296240 | Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer | unknown | Phase 2 | 119 | Peking University Cancer Hospital & InstituteOTHER | 1 | Mar 5, 2020 | clinicaltrials |
| NCT02425683 | Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX | terminated | Phase 2 | 24 | US Oncology ResearchINDUSTRY | 1 | Feb 10, 2020 | clinicaltrials |
| NCT03022734 | Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis | unknown | Phase 2 | 40 | Yonsei UniversityOTHER | 1 | Jan 13, 2020 | clinicaltrials |
| NCT00580073 | Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum | terminated | Phase 2 | 6 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT04170530 | Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer | unknown | Phase 2 | 51 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Nov 20, 2019 | clinicaltrials |
| NCT01650428 | Bevacizumab And Combination Chemotherapy in Rectal Cancer Until Surgery(BACCHUS) | completed | Phase 2 | 20 | University College, LondonOTHER | 1 | Oct 7, 2019 | clinicaltrials |
| NCT01806675 | 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy | completed | Phase 1 / Phase 2 | 25 | Sanjiv Sam GambhirOTHER | 1 | Oct 3, 2019 | clinicaltrials |
| NCT03053544 | Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer | completed | Phase 2 | 15 | Sunnybrook Health Sciences CentreOTHER | 1 | Sep 27, 2019 | clinicaltrials |
| NCT01802320 | Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery | completed | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Sep 20, 2019 | clinicaltrials |
| NCT01923987 | Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis | unknown | Phase 2 | 39 | Korea Cancer Center HospitalOTHER | 1 | Sep 20, 2019 | clinicaltrials |
| NCT00397878 | AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer | terminated | Phase 2 | 10 | National Cancer Institute (NCI)NIH | 1 | Aug 20, 2019 | clinicaltrials |
| NCT03204201 | Validation of ICG to Identify the Urethra During Rectal Surgery | terminated | Phase 1 / Phase 2 | 5 | Oxford University Hospitals NHS TrustOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03204994 | Fluorescence Targeted Pelvic Lymph Node Mapping | terminated | Phase 1 / Phase 2 | 1 | Oxford University Hospitals NHS TrustOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03161574 | FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin (CRM) Positive Rectal Cancer | withdrawn | Phase 2 | 0 | Guangxi Medical UniversityOTHER | 1 | Aug 8, 2019 | clinicaltrials |
| NCT01111604 | A Study of Ramucirumab or Icrucumab in Colorectal Cancer | completed | Phase 2 | 158 | Eli Lilly and CompanyINDUSTRY | 2 | Aug 6, 2019 | clinicaltrials |
| NCT02973672 | Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas | completed | Phase 1 / Phase 2 | 75 | SurgimabINDUSTRY | 1 | Jul 18, 2019 | clinicaltrials |
| NCT00828672 | Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer(AXEBEAM) | completed | Phase 2 | 84 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 10, 2019 | clinicaltrials |
| NCT01047969 | Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy | unknown | Phase 2 | 99 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 13, 2019 | clinicaltrials |
| NCT01985763 | Genistein in Treatment of Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 13 | Sofya PintovaOTHER | 1 | May 10, 2019 | clinicaltrials |
| NCT01206530 | FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer | completed | Phase 1 / Phase 2 | 50 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 18, 2019 | clinicaltrials |
| NCT00645710 | Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery | completed | Phase 1 / Phase 2 | 16 | City of Hope Medical CenterOTHER | 1 | Mar 28, 2019 | clinicaltrials |
| NCT00321685 | Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer | completed | Phase 2 | 57 | National Cancer Institute (NCI)NIH | 1 | Mar 27, 2019 | clinicaltrials |
| NCT01717391 | [F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers | completed | Phase 2 | 36 | John M. BuattiOTHER | 1 | Mar 26, 2019 | clinicaltrials |
| NCT00409994 | Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer | completed | Phase 1 / Phase 2 | 44 | Maastricht Radiation OncologyOTHER | 1 | Mar 18, 2019 | clinicaltrials |
| NCT02584400 | Tumor Hypoxia With HX4 PET in Several Diseases(HX4 SD) | terminated | Phase 2 | 1 | Maastricht Radiation OncologyOTHER | 1 | Mar 8, 2019 | clinicaltrials |
| NCT02648386 | Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery | unknown | Phase 1 / Phase 2 | 34 | Chinese Academy of SciencesOTHER_GOV | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03040180 | Endoscopic Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer(nECT) | unknown | Phase 2 | 40 | Zealand University HospitalOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03702985 | Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer | unknown | Phase 2 | 160 | Fudan UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT00611858 | Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer | terminated | Phase 2 | 13 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 8, 2019 | clinicaltrials |
| NCT00257322 | Cellular Immune Augmentation in Colon and Rectal Cancer | completed | Phase 2 | 20 | University of California, IrvineOTHER | 1 | Oct 31, 2018 | clinicaltrials |
| NCT00094809 | Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer | completed | Phase 2 | 252 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT00418938 | SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial | completed | Phase 2 | 266 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT01037049 | Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks | unknown | Phase 2 | 237 | Royal Marsden NHS Foundation TrustOTHER | 4 | Sep 17, 2018 | clinicaltrials |
| NCT02216149 | Effects of S-1 and Capecitabine on Coronary Artery Blood Flow(FluoHeart) | terminated | Phase 2 | 20 | Heikki JoensuuOTHER | 1 | Aug 28, 2018 | clinicaltrials |
| NCT01613469 | Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer | terminated | Phase 2 | 5 | Marks, John, M.D.INDIV | 1 | Aug 16, 2018 | clinicaltrials |
| NCT02919878 | Neo-adjuvant Chemoradiotherapy Using Infusional Gemcitabine Followed by Surgery for Locally Advanced Rectal Cancer | unknown | Phase 2 | 25 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT00845039 | A Study of Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants With Colon or Rectum Cancer Who Got Worse After Their First Treatment With Oxaliplatin and Bevacizumab(FC-4) | terminated | Phase 2 | 4 | Eli Lilly and CompanyINDUSTRY | 1 | Jul 2, 2018 | clinicaltrials |
| NCT03561142 | Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy.(CAO/ARO/AIO-16) | unknown | Phase 2 | 94 | University Hospital TuebingenOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT03085992 | Folfoxiri Plus Bevacizumab Followed by Chemoradiotherapy Plus Bevacizumab in Patients With Resectable Rectal Cancer(TRUST) | completed | Phase 2 | 49 | Azienda Ospedaliero, Universitaria PisanaOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT00832299 | Neo-Adjuvant FOLFOX for Rectal Carcinoma | terminated | Phase 2 | 2 | Beth Israel Medical CenterOTHER | 1 | Mar 1, 2018 | clinicaltrials |
| NCT02353858 | Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer(HT01) | completed | Phase 2 | 78 | University Hospital TuebingenOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT01589471 | The Value of Botox-A for Management of Low Anterior Resection Syndrome | completed | Phase 2 | 23 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Feb 12, 2018 | clinicaltrials |
| NCT03428529 | Capecitabine Versus Bolus 5-Fu Associated to Radiotherapy as Neoadjuvant Treatment for Rectal Cancer.(INCAGI004) | completed | Phase 2 / Phase 3 | 63 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 0 | Feb 9, 2018 | clinicaltrials |
| NCT03422835 | Robotic Assisted Transanal Total Mesorectal Excision Surgery for Rectal Cancer in Low Site | unknown | Phase 2 | 50 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 0 | Feb 6, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT01729923 | A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer(ADAPT) | terminated | Phase 2 | 27 | University of WashingtonOTHER | 1 | Jan 16, 2018 | clinicaltrials |
Data updated 23 days agoSource updated Apr 9, 2020source: clinicaltrials