Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
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Subtype
CI-CAN-00001432Explore in graph →
Clinical trials
3,293 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01957956 | Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma | completed | Early Phase 1 | 21 | Mayo ClinicOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT05054400 | Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR | withdrawn | Early Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 1, 2023 | clinicaltrials |
| NCT05802693 |
| A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma |
| unknown |
| Early Phase 1 |
| 22 |
| Beijing Tsinghua Chang Gung HospitalOTHER |
| 0 |
| Aug 25, 2023 |
| clinicaltrials |
| NCT03360708 | Vaccine Therapy in Treating Patients With Recurrent Glioblastoma | completed | Early Phase 1 | 20 | Mayo ClinicOTHER | 1 | Jun 28, 2023 | clinicaltrials |
| NCT04114370 | Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma(FACBC) | completed | Early Phase 1 | 9 | James MountzOTHER | 1 | Dec 6, 2022 | clinicaltrials |
| NCT05017610 | Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma | withdrawn | Early Phase 1 | 0 | Emory UniversityOTHER | 0 | Dec 2, 2022 | clinicaltrials |
| NCT05589961 | Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme | unknown | Early Phase 1 | 10 | The Second Hospital of Hebei Medical UniversityOTHER | 1 | Oct 21, 2022 | clinicaltrials |
| NCT04776980 | Multimodality MRI and Liquid Biopsy in GBM | withdrawn | Early Phase 1 | 0 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Sep 16, 2022 | clinicaltrials |
| NCT03020017 | NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery | completed | Early Phase 1 | 8 | Northwestern UniversityOTHER | 1 | Aug 26, 2022 | clinicaltrials |
| NCT02885272 | FDG PET Imaging in Diagnosing Patients With Glioblastoma | completed | Early Phase 1 | 21 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 21, 2022 | clinicaltrials |
| NCT05459441 | Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases | unknown | Early Phase 1 | 30 | Shanghai Pudong HospitalOTHER | 1 | Jul 15, 2022 | clinicaltrials |
| NCT05333588 | The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme. | unknown | Early Phase 1 | 20 | Hebei Senlang Biotechnology Inc., Ltd.INDUSTRY | 1 | Apr 19, 2022 | clinicaltrials |
| NCT05061251 | Surgical Window of Opportunity Study of Orally Administered BAY 2402234 in Recurrent Glioma | withdrawn | Early Phase 1 | 0 | University of Texas Southwestern Medical CenterOTHER | 0 | Jan 11, 2022 | clinicaltrials |
| NCT01331616 | Optic Neuropathy in 10 Patients With Glioblastoma Receiving Bevacizumab | withdrawn | Early Phase 1 | 0 | West Penn Allegheny Health SystemOTHER | 0 | Dec 9, 2021 | clinicaltrials |
| NCT03291990 | 5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme | completed | Early Phase 1 | 3 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 19, 2021 | clinicaltrials |
| NCT02212574 | Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma | terminated | Early Phase 1 | 6 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 5, 2021 | clinicaltrials |
| NCT03861598 | Carvedilol With Chemotherapy in Second Line Glioblastoma and Response of Circulating Tumor Cells | terminated | Early Phase 1 | 4 | West Virginia UniversityOTHER | 1 | Sep 24, 2021 | clinicaltrials |
| NCT03347097 | Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme | unknown | Early Phase 1 | 40 | Huashan HospitalOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT03980249 | Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells | withdrawn | Early Phase 1 | 0 | West Virginia UniversityOTHER | 1 | Apr 12, 2021 | clinicaltrials |
| NCT02630030 | Phase 0 Analysis of Ixazomib (MLN9708) in Patients With Glioblastoma | completed | Early Phase 1 | 3 | Emory UniversityOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT03001349 | 68Ga-DOTA-TOC PET/CT in Imaging Participants With Neuroendocrine Tumors | terminated | Early Phase 1 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 15, 2021 | clinicaltrials |
| NCT02605746 | Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis | completed | Early Phase 1 | 10 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 11, 2020 | clinicaltrials |
| NCT02207010 | A Phase 0 Study of AZD1775 in Recurrent GBM Patients | completed | Early Phase 1 | 20 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 10, 2020 | clinicaltrials |
| NCT03151772 | Bioavailability of Disulfiram and Metformin in Glioblastomas(INSIDE) | terminated | Early Phase 1 | 3 | Sahlgrenska University HospitalOTHER | 1 | Sep 28, 2020 | clinicaltrials |
| NCT04220892 | Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma | withdrawn | Early Phase 1 | 0 | Jose CarrilloOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT02507232 | Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas | terminated | Early Phase 1 | 2 | Santosh KesariOTHER | 1 | Jul 28, 2020 | clinicaltrials |
| NCT04417933 | Tumor Electric Fields Treatment System for Glioblastoma | unknown | Early Phase 1 | 5 | Xiangya Hospital of Central South UniversityOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT01880749 | Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas | completed | Early Phase 1 | 5 | NYU Langone HealthOTHER | 1 | May 13, 2020 | clinicaltrials |
| NCT04045847 | CD147-CART Cells in Patients With Recurrent Malignant Glioma. | unknown | Early Phase 1 | 31 | Xijing HospitalOTHER | 1 | May 7, 2020 | clinicaltrials |
| NCT02077543 | Multicenter Safety Trial Assessing an Innovative Tumor Molecular and Cellular Print Medical Device in Glioma(ProTool) | unknown | Early Phase 1 | 150 | University Hospital, GrenobleOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT04315584 | FDG and FDOPA PET Demonstration of Functional Brain Abnormalities | unknown | Early Phase 1 | 5 | University of VirginiaOTHER | 1 | Mar 24, 2020 | clinicaltrials |
| NCT04051047 | Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma | withdrawn | Early Phase 1 | 0 | University of Michigan Rogel Cancer CenterOTHER | 1 | Nov 27, 2019 | clinicaltrials |
| NCT00795457 | Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas | completed | Early Phase 1 | 13 | Ian F. Pollack, M.D.OTHER | 1 | Aug 30, 2019 | clinicaltrials |
| NCT02768389 | Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma | completed | Early Phase 1 | 18 | Case Comprehensive Cancer CenterOTHER | 1 | Mar 15, 2019 | clinicaltrials |
| NCT02500459 | Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection | terminated | Early Phase 1 | 9 | Michael Vogelbaum, MD, PhDOTHER | 1 | Mar 1, 2019 | clinicaltrials |
| NCT03193463 | Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy | withdrawn | Early Phase 1 | 0 | Michael Vogelbaum, MD, PhDOTHER | 0 | Mar 1, 2019 | clinicaltrials |
| NCT01907165 | Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide | completed | Early Phase 1 | 21 | Washington University School of MedicineOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01086345 | Radiosurgery Plus Bevacizumab in Glioblastoma | terminated | Early Phase 1 | 9 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT01091792 | Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM) | completed | Early Phase 1 | 13 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 25, 2018 | clinicaltrials |
| NCT00890786 | A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas | completed | Early Phase 1 | 27 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | May 2, 2018 | clinicaltrials |
| NCT02466828 | qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia. | completed | Early Phase 1 | 10 | Sunnybrook Health Sciences CentreOTHER | 1 | Apr 18, 2018 | clinicaltrials |
| NCT02910804 | IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Glioblastoma | unknown | Early Phase 1 | 30 | Beijing Tiantan HospitalOTHER | 1 | Jan 18, 2018 | clinicaltrials |
| NCT01867593 | MET-PET for Newly Diagnosed Glioblastoma | completed | Early Phase 1 | 20 | Massachusetts General HospitalOTHER | 1 | Oct 13, 2017 | clinicaltrials |
| NCT02490930 | A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade Glioma | completed | Early Phase 1 | 5 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Sep 13, 2017 | clinicaltrials |
| NCT02279992 | Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases(LevitraCarbo) | terminated | Early Phase 1 | 7 | Cedars-Sinai Medical CenterOTHER | 1 | Sep 11, 2017 | clinicaltrials |
| NCT02452216 | Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS | completed | Early Phase 1 | 10 | Michael IvOTHER | 1 | Aug 31, 2017 | clinicaltrials |
| NCT01996527 | 3T MRI Biomarkers of Glioma Treatment Response | terminated | Early Phase 1 | 7 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT01801371 | 68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma(GRGDG) | unknown | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Apr 7, 2017 | clinicaltrials |
| NCT02520882 | 68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas | unknown | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Apr 7, 2017 | clinicaltrials |
Data updated 23 days agoSource updated Nov 18, 2023source: clinicaltrials