Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,873 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01417507 | Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery | completed | — | 82 | Radiation Therapy Oncology GroupNETWORK | 2 | Mar 18, 2015 | clinicaltrials |
| NCT01582516 | Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma | completed | Phase 1 / Phase 2 | 20 | Erasmus Medical CenterOTHER | 1 | Mar 9, 2015 |
| clinicaltrials |
| NCT00187174 | Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors | completed | Phase 1 | 41 | St. Jude Children's Research HospitalOTHER | 1 | Mar 4, 2015 | clinicaltrials |
| NCT00179907 | A Phase I/II Study of the Photon Radiosurgery System | completed | Phase 1 / Phase 2 | 35 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Mar 2, 2015 | clinicaltrials |
| NCT01518413 | Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors | completed | Phase 1 | 17 | HMeanyOTHER | 1 | Feb 27, 2015 | clinicaltrials |
| NCT00221325 | A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma | completed | Phase 1 | 14 | University of California, San FranciscoOTHER | 1 | Feb 16, 2015 | clinicaltrials |
| NCT01017497 | Optimal Planning Target Volume With Stereotactic Radiosurgery | completed | N/A | 49 | Duke UniversityOTHER | 1 | Feb 13, 2015 | clinicaltrials |
| NCT00082758 | hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma | completed | Phase 2 | 39 | Children's Oncology GroupNETWORK | 2 | Feb 12, 2015 | clinicaltrials |
| NCT01853345 | iCAT for Recurrent/Refractory/HR Solid Tumors | completed | — | 101 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 10, 2015 | clinicaltrials |
| NCT00952081 | A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients | completed | Phase 4 | 22 | NYU Langone HealthOTHER | 1 | Feb 9, 2015 | clinicaltrials |
| NCT00723827 | Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) | completed | — | 682 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jan 30, 2015 | clinicaltrials |
| NCT01738880 | Effect of Goal-directed Fluid Therapy Based on Stroke Volume Variation on Metabolic Acidosis in Patients Undergoing Brain Tumor Surgery | completed | N/A | 50 | Yonsei UniversityOTHER | 1 | Jan 28, 2015 | clinicaltrials |
| NCT01578668 | Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases | completed | Phase 2 | 69 | Guangzhou Medical UniversityOTHER | 1 | Jan 26, 2015 | clinicaltrials |
| NCT01386580 | An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. | completed | Phase 1 / Phase 2 | 84 | BBB-Therapeutics B.V.INDUSTRY | 4 | Jan 22, 2015 | clinicaltrials |
| NCT01447810 | Constraint-Induced Movement Therapy in a Pediatric Oncology Population(SJCIT) | completed | N/A | 10 | St. Jude Children's Research HospitalOTHER | 1 | Jan 14, 2015 | clinicaltrials |
| NCT00876499 | Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients | completed | — | 20 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 9, 2015 | clinicaltrials |
| NCT00734682 | A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas | completed | Phase 1 | 34 | University of California, San FranciscoOTHER | 1 | Jan 7, 2015 | clinicaltrials |
| NCT01218529 | Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors | completed | Phase 2 | 82 | Hellenic Cooperative Oncology GroupOTHER | 1 | Dec 31, 2014 | clinicaltrials |
| NCT00893945 | Autologous Dendritic Cells Pulsed With Autologous Apoptotic Tumor Cells Administered to Patients With Brain Tumors | completed | Phase 1 | 19 | Rockefeller UniversityOTHER | 1 | Dec 23, 2014 | clinicaltrials |
| NCT01131234 | Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 20 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT02227901 | Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT00681551 | Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | completed | Phase 3 | 45 | BayerINDUSTRY | 1 | Dec 15, 2014 | clinicaltrials |
| NCT01115491 | A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 2 | 32 | Hoffmann-La RocheINDUSTRY | 1 | Dec 8, 2014 | clinicaltrials |
| NCT01689064 | Comparison of Surgical Approach to Endoscopic Pituitary Adenoma Resection | completed | N/A | 55 | University of CalgaryOTHER | 1 | Dec 3, 2014 | clinicaltrials |
| NCT00213278 | Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma | completed | Phase 2 | 50 | The Hospital for Sick ChildrenOTHER | 1 | Nov 20, 2014 | clinicaltrials |
| NCT00024570 | Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 60 | INSYS Therapeutics IncINDUSTRY | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00331643 | Ixabepilone in Treating Young Patients With Refractory Solid Tumors | completed | Phase 2 | 120 | National Cancer Institute (NCI)NIH | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00525525 | Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcoma(AVF4120s) | completed | Phase 2 | 74 | University of California, San FranciscoOTHER | 1 | Nov 14, 2014 | clinicaltrials |
| NCT01412892 | Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas(NFitor) | completed | Phase 2 | 30 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 14, 2014 | clinicaltrials |
| NCT01158274 | RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 2 | Nov 7, 2014 | clinicaltrials |
| NCT00689221 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status(CENTRIC) | completed | Phase 3 | 545 | EMD SeronoINDUSTRY | 2 | Nov 4, 2014 | clinicaltrials |
| NCT00884416 | Sorafenib in Newly Diagnosed High Grade Glioma | completed | Phase 1 | 17 | University Hospital, GenevaOTHER | 1 | Nov 4, 2014 | clinicaltrials |
| NCT00576641 | Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma | completed | Phase 1 | 22 | Cedars-Sinai Medical CenterOTHER | 1 | Oct 30, 2014 | clinicaltrials |
| NCT01770626 | A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients(BEAM) | completed | Early Phase 1 | 40 | University of Alabama at BirminghamOTHER | 1 | Oct 28, 2014 | clinicaltrials |
| NCT00411619 | Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex | completed | Phase 1 / Phase 2 | 28 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Oct 20, 2014 | clinicaltrials |
| NCT00098865 | Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma | completed | Phase 2 | 15 | Dana-Farber Cancer InstituteOTHER | 1 | Oct 7, 2014 | clinicaltrials |
| NCT00528684 | Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas | completed | Phase 1 | 18 | Oncolytics BiotechINDUSTRY | 1 | Oct 2, 2014 | clinicaltrials |
| NCT00357500 | Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer | completed | Phase 2 | 101 | Dana-Farber Cancer InstituteOTHER | 1 | Oct 1, 2014 | clinicaltrials |
| NCT00311584 | Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma | completed | Phase 2 | 59 | Children's Oncology GroupNETWORK | 3 | Sep 30, 2014 | clinicaltrials |
| NCT00960492 | Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma | completed | Phase 1 | 26 | ExelixisINDUSTRY | 1 | Sep 22, 2014 | clinicaltrials |
| NCT00003107 | Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors | completed | Phase 1 | — | Indiana UniversityOTHER | 1 | Sep 10, 2014 | clinicaltrials |
| NCT01006044 | Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection | completed | Phase 2 | 26 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 1 | Sep 3, 2014 | clinicaltrials |
| NCT01951950 | Nicardipine vs Esmolol Craniotomy Emergence | completed | Phase 1 | 40 | Northwestern UniversityOTHER | 1 | Aug 29, 2014 | clinicaltrials |
| NCT00003461 | Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors | completed | Phase 1 / Phase 2 | — | Duke UniversityOTHER | 1 | Aug 21, 2014 | clinicaltrials |
| NCT00293319 | 131 I-MIBG in Treating Patients With Refractory or Relapsed Neuroblastoma | completed | Phase 2 | 164 | University of California, San FranciscoOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT00565721 | A Proof-of-concept Study to Assess the Ability of [18F]AH-111585 PET Imaging to Detect Tumours and Angiogenesis | completed | Phase 2 | 33 | GE HealthcareINDUSTRY | 1 | Aug 18, 2014 | clinicaltrials |
| NCT00616005 | Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide | completed | Phase 2 | 41 | Duke UniversityOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT01380782 | BIBF 1120 for Recurrent High-Grade Gliomas | completed | Phase 2 | 37 | Patrick Y. Wen, MDOTHER | 1 | Aug 18, 2014 | clinicaltrials |
| NCT00941460 | Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma(DIRECTOR) | completed | Phase 2 | 105 | Prof. Dr. Wolfgang WickOTHER | 3 | Aug 15, 2014 | clinicaltrials |
| NCT00088166 | XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | completed | Phase 3 | 200 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 13, 2014 | clinicaltrials |
Data updated 23 days agoSource updated Mar 18, 2015source: clinicaltrials