Cancer
Neoplasm of Uncertain Histogenesis
CI-CAN-00000034Explore in graph →
Non-malignant20,280 active trials259 approved drugs3,813 evidence items
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Cancer
CI-CAN-00000034Explore in graph →
Clinical trials
91,351 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07198659 | A Single-Arm Investigator-Initiated Tria (IIT) Evaluating the Safety and Preliminary Efficacy of Autologous Drug-Loaded Neutrophils (NeuMed) in Patients With Unresectable Pancreatic Cancer(NeuMed-uPC) | recruiting | Early Phase 1 | 3 | The First Affiliated Hospital of Air Force Medicial UniversityOTHER | 1 | Sep 30, 2025 | clinicaltrials |
| NCT02245997 | Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma | completed | Early Phase 1 | 78 | Memorial Sloan Kettering Cancer Center |
| 1 |
| Sep 29, 2025 |
| clinicaltrials |
| NCT06516510 | A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto®) in Patients With Non-curative Metastatic Prostate Cancer | terminated | Early Phase 1 | 17 | Blue Earth Therapeutics LtdINDUSTRY | 3 | Sep 25, 2025 | clinicaltrials |
| NCT06520449 | 68Ga-NTA-476 Imaging in Prostate Cancer(NTA-476) | completed | Early Phase 1 | 10 | Melbourne Theranostic Innovation CentreNETWORK | 1 | Sep 25, 2025 | clinicaltrials |
| NCT05488366 | Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma | active not recruiting | Early Phase 1 | 9 | University of California, IrvineOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT05634707 | Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT) | active not recruiting | Early Phase 1 | 10 | Duke UniversityOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT07185477 | A Single-arm Single-center Trial of Bridging GPRC5D/CD3 Bispecific Antibody Treatment With BCMA CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma(QLS32015) | not yet recruiting | Early Phase 1 | 20 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 0 | Sep 22, 2025 | clinicaltrials |
| NCT02467738 | Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer | completed | Early Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT06120166 | Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r DLBCL Clinical Research | recruiting | Early Phase 1 | 18 | He HuangOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT06328686 | Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases | recruiting | Early Phase 1 | 10 | Emory UniversityOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT07168291 | Novel Bispecific AbTCR (Anti-CD19/CD22)-T Cells in Relapsed or Refractory B-cell Lymphoma | not yet recruiting | Early Phase 1 | 3 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT07172178 | γδ T-PD-1 Ab Cells in the Treatment of Malignant Meningioma | not yet recruiting | Early Phase 1 | 12 | Nanjing Medical UniversityOTHER | 0 | Sep 15, 2025 | clinicaltrials |
| NCT06552260 | A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma | recruiting | Early Phase 1 | 27 | Ugonma ChukwuekeOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT04862676 | Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT | completed | Early Phase 1 | 29 | University of RochesterOTHER | 1 | Sep 10, 2025 | clinicaltrials |
| NCT07166263 | Safety and Efficacy of NK510 to Treat Gastric Cancer and Colorectal Cancer | not yet recruiting | Early Phase 1 | 15 | Base Therapeutics (Shanghai) Co., Ltd.INDUSTRY | 1 | Sep 10, 2025 | clinicaltrials |
| NCT03802604 | Combination of Talimogene Laherparepvec With Atezolizumab in Early Breast Cancer(PROMETEO) | completed | Early Phase 1 | 28 | SOLTI Breast Cancer Research GroupOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT01165632 | Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma | completed | Early Phase 1 | 24 | Mayo ClinicOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT04576871 | Re-treatment 225Ac-J591 for mCRPC | completed | Early Phase 1 | 6 | Weill Medical College of Cornell UniversityOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT07144020 | Donor Derived CD117 CAR-T Cells in the Treatment of R/R Acute Myeloid Leukemia | recruiting | Early Phase 1 | 50 | Zhejiang UniversityOTHER | 1 | Aug 27, 2025 | clinicaltrials |
| NCT03039413 | Copper Cu-64 TP3805 PET/CT in Imaging Patients With Urothelial Cancer Undergoing Surgery or Biopsy | completed | Early Phase 1 | 20 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT04200534 | Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study) | active not recruiting | Early Phase 1 | 358 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT05105087 | Gynecological Sentinel Lymph Nodes CEUS | completed | Early Phase 1 | 9 | Thomas Jefferson UniversityOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT06446128 | A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL) | recruiting | Early Phase 1 | 20 | Shanghai Cell Therapy Group Co.,LtdINDUSTRY | 1 | Aug 21, 2025 | clinicaltrials |
| NCT05802121 | Akkermansia Muciniphilia and Metabolic Side Effects of ADT | recruiting | Early Phase 1 | 30 | Western UniversityOTHER | 1 | Aug 20, 2025 | clinicaltrials |
| NCT02652455 | Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma | completed | Early Phase 1 | 11 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT04074785 | Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6(SCCC-06319) | terminated | Early Phase 1 | 10 | University of Texas Southwestern Medical CenterOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT05678348 | Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma | completed | Early Phase 1 | 22 | Washington University School of MedicineOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT07126782 | The Efficacy and Safety Assessment of Allogeneic γδ T Cells in Patients With MRD-positive AML After Allo-HSCT | recruiting | Early Phase 1 | 10 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT05779930 | Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL | not yet recruiting | Early Phase 1 | 12 | Nationwide Children's HospitalOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06273852 | A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors | completed | Early Phase 1 | 8 | Pure Biologics S.A.INDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT06700070 | A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors | recruiting | Early Phase 1 | 12 | Pure Biologics S.A.INDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT07113977 | Clinical Study of a Novel Humanized CD70-Targeted CAR-T Cell Incorporating TLR2 for Advanced Renal Cell Carcinoma Therapy | not yet recruiting | Early Phase 1 | 30 | Wei GuanOTHER | 0 | Aug 11, 2025 | clinicaltrials |
| NCT07026981 | [Ga-68]MTP220 PET for Biodistribution and Efficacy in Pancreatic Cancer and Head and Neck Cancers | not yet recruiting | Early Phase 1 | 12 | Qiubai LiOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT04301414 | Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer(Neo-Red-P) | completed | Early Phase 1 | 26 | Columbia UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT03957915 | Study of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute Leukemia(INA03) | completed | Early Phase 1 | 33 | Institut Paoli-CalmettesOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT03579446 | Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer | terminated | Early Phase 1 | 43 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT06988059 | A Study of CT0596 in Plasma Cell Leukemia | recruiting | Early Phase 1 | 27 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT05859971 | ICG and SLN Mapping | completed | Early Phase 1 | 10 | University of Wisconsin, MadisonOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT07067346 | Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma | recruiting | Early Phase 1 | 10 | Sichuan UniversityOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT07090538 | GSL Synthetase Inhibitor Plus GM-CSF and/ or Immune Checkpoint Inhibitor in Previously Treated High-Risk Neuroblastoma. | not yet recruiting | Early Phase 1 | 10 | Chinese PLA General HospitalOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT05049785 | Nutrition and Physical Activity Intervention in Preventing Excess Weight Gain in Pediatric Patients With Leukemia or Lymphoma Treated With Prednisone and/or Dexamethasone | completed | Early Phase 1 | 100 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07085559 | Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research | recruiting | Early Phase 1 | 36 | Anhui Provincial HospitalOTHER_GOV | 1 | Jul 25, 2025 | clinicaltrials |
| NCT04135807 | Implantable Microdevice In Primary Brain Tumors | recruiting | Early Phase 1 | 12 | Oliver JonasOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT06827886 | GPNMB-targeting Chimeric Antigen Receptor T-Cell Therapy (GCAR1) for a Patient With Alveolar Soft Part Sarcoma(GCAR1) | completed | Early Phase 1 | 1 | AHS Cancer Control AlbertaOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT06246786 | Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer) | withdrawn | Early Phase 1 | 0 | Virginia G. KaklamaniOTHER | 1 | Jul 16, 2025 | clinicaltrials |
| NCT07069465 | Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging(PIONEER PSMA) | completed | Early Phase 1 | 10 | Urology Clinics of North TexasNETWORK | 1 | Jul 16, 2025 | clinicaltrials |
| NCT07066436 | ImmunoMRI for Assessment of Tumor-associated Macrophages | not yet recruiting | Early Phase 1 | 60 | Medical University of ViennaOTHER | 1 | Jul 15, 2025 | clinicaltrials |
| NCT03335670 | Gallium 68 Pentixafor in Patients With Neuroendocrine Tumors | active not recruiting | Early Phase 1 | 30 | Yusuf MendaOTHER | 1 | Jul 14, 2025 | clinicaltrials |
| NCT05111509 | A First-in-human Clinical Trial to Evaluate an Alpha-radiation Imaging Agent | active not recruiting | Early Phase 1 | 20 | Yusuf MendaOTHER | 1 | Jul 14, 2025 | clinicaltrials |
| NCT03893487 | Fimepinostat in Treating Brain Tumors in Children and Young Adults(PNOC016) | active not recruiting | Early Phase 1 | 30 | Sabine Mueller, MD, PhDOTHER | 2 | Jul 11, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Sep 30, 2025source: clinicaltrials