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Non-malignant20,504 active trials253 approved drugs3,568 evidence items
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Other
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Clinical trials
92,622 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02952586 | Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100) | terminated | Phase 3 | 697 | PfizerINDUSTRY | 22 | Sep 22, 2021 | clinicaltrials |
| NCT00508274 | Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China | terminated | Phase 3 | 52 | Novartis PharmaceuticalsINDUSTRY | 2 | Sep 21, 2021 |
| clinicaltrials |
| NCT01439347 | A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL | terminated | Phase 3 | 26 | Spectrum Pharmaceuticals, IncINDUSTRY | 1 | Sep 9, 2021 | clinicaltrials |
| NCT00992030 | R-ABVD vs ABVD-RT in Early Stage Hodgkin's Lymphoma | terminated | Phase 3 | 112 | Fondazione MichelangeloOTHER | 2 | Aug 19, 2021 | clinicaltrials |
| NCT01956812 | Phase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic Cancer(PANCRIT®-1) | terminated | Phase 3 | 334 | Gilead SciencesINDUSTRY | 8 | Aug 16, 2021 | clinicaltrials |
| NCT03326674 | Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/MBC(CONTESSA) | terminated | Phase 3 | 685 | Odonate Therapeutics, Inc.INDUSTRY | 19 | Jul 30, 2021 | clinicaltrials |
| NCT03033511 | A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)(MERU) | terminated | Phase 3 | 748 | AbbVieINDUSTRY | 41 | Jul 29, 2021 | clinicaltrials |
| NCT03393000 | Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects(INTACT) | terminated | Phase 3 | 19 | Diffusion Pharmaceuticals IncINDUSTRY | 1 | Jul 22, 2021 | clinicaltrials |
| NCT02579863 | Study of Lenalidomide and Dexamethasone With or Without Pembrolizumab (MK-3475) in Participants With Newly Diagnosed Treatment Naive Multiple Myeloma (MK-3475-185/KEYNOTE-185) | terminated | Phase 3 | 310 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jul 20, 2021 | clinicaltrials |
| NCT03682367 | Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery | terminated | Phase 3 | 8 | University of California, DavisOTHER | 1 | Jul 9, 2021 | clinicaltrials |
| NCT01767857 | A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer(XCITE) | terminated | Phase 3 | 643 | Janssen Research & Development, LLCINDUSTRY | 13 | Jun 29, 2021 | clinicaltrials |
| NCT00577317 | Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial Cancer | terminated | Phase 3 | 2 | Gynecologic Oncology GroupNETWORK | 1 | Jun 23, 2021 | clinicaltrials |
| NCT00914628 | Efficacy Study on the Strategy of HSV-Tk Engineering Donor Lymphocytes to Treat Patients With High Risk Acute Leukemia(TK008) | terminated | Phase 3 | 92 | AGC Biologics S.p.A.INDUSTRY | 10 | Jun 22, 2021 | clinicaltrials |
| NCT03905343 | Ribociclib-endocrine Combination Therapy Versus Chemotherapy as 1st Line in Visceral mBC | terminated | Phase 3 | 25 | Swiss Cancer InstituteOTHER | 3 | Jun 16, 2021 | clinicaltrials |
| NCT00967343 | Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor | terminated | Phase 2 / Phase 3 | 40 | Kiadis PharmaINDUSTRY | 7 | Jun 14, 2021 | clinicaltrials |
| NCT01437514 | Effective Study of Preoperative Short-course Radiotherapy for the Advanced Resectable Rectal Cancer | terminated | Phase 2 / Phase 3 | 410 | West China HospitalOTHER | 1 | Jun 7, 2021 | clinicaltrials |
| NCT02768558 | Cisplatin and Etoposide Plus Radiation Followed By Nivolumab/Placebo For Locally Advanced NSCLC | terminated | Phase 3 | 20 | RTOG Foundation, Inc.OTHER | 1 | Jun 2, 2021 | clinicaltrials |
| NCT03532308 | Nutrition and Prostate Cancer | terminated | Phase 3 | 19 | Yale UniversityOTHER | 1 | May 26, 2021 | clinicaltrials |
| NCT00003056 | Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation | terminated | Phase 3 | 105 | Baxalta now part of ShireINDUSTRY | 2 | May 6, 2021 | clinicaltrials |
| NCT01126216 | Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer(Paccis-RCT) | terminated | Phase 3 | 221 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | May 4, 2021 | clinicaltrials |
| NCT02644252 | Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer(Toco-Pulm) | terminated | Phase 3 | 79 | Vejle HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT03158610 | Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer | terminated | Phase 2 / Phase 3 | 20 | Ruijin HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT02057666 | Study Of Tasquinimod In Asian Chemo-Naïve Patients With Metastatic Castrate-Resistant Prostate Cancer(TasQ003) | terminated | Phase 3 | 146 | IpsenINDUSTRY | 3 | Apr 23, 2021 | clinicaltrials |
| NCT01887717 | Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein(YES-P) | terminated | Phase 3 | 36 | Boston Scientific CorporationINDUSTRY | 6 | Apr 21, 2021 | clinicaltrials |
| NCT01438112 | Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer(BOND) | terminated | Phase 2 / Phase 3 | 22 | CG Oncology, Inc.INDUSTRY | 1 | Apr 14, 2021 | clinicaltrials |
| NCT03419403 | UNITE Study: Understanding New Interventions With GBM ThErapy | terminated | Phase 3 | 40 | AbbVieINDUSTRY | 5 | Apr 14, 2021 | clinicaltrials |
| NCT01244191 | Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung Cancer | terminated | Phase 3 | 1,048 | Daiichi SankyoINDUSTRY | 23 | Apr 6, 2021 | clinicaltrials |
| NCT03440411 | Pom-dex Versus Pom-Cyclo-dex in MM Patients With Biochemical or Clinical Relapse, During Lena Maintenance Treatment(PO-3887) | terminated | Phase 3 | 9 | Fondazione EMN Italy OnlusOTHER | 1 | Mar 10, 2021 | clinicaltrials |
| NCT00296010 | Liposomal Doxorubicin Compared With Observation or Cyclophosphamide and Methotrexate in Treating Older Women Who Have Undergone Surgery for Breast Cancer(CASA) | terminated | Phase 3 | 77 | ETOP IBCSG Partners FoundationNETWORK | 9 | Feb 23, 2021 | clinicaltrials |
| NCT01318161 | Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery(EPICOL) | terminated | Phase 3 | 221 | Örebro University, SwedenOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT02460991 | A Study of ONCO-DOX in Locally Advanced Hepatocellular Carcinoma(SOLACE) | terminated | Phase 3 | 2 | Boston Scientific CorporationINDUSTRY | 1 | Feb 12, 2021 | clinicaltrials |
| NCT02893332 | Stereotactic Body Radiation Therapy (SBRT) in Newly Diagnosed Advanced Staged Lung Adenocarcinoma (Sindas)(Sindas) | terminated | Phase 3 | 200 | Sichuan Provincial People's HospitalOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT02730091 | A Open Study of Metronomic Oral Vinorelbine in Combination With Aromatase Inhibitors for the Treatment of Postmenopausal Women With Hormone Receptor Positive,HER2-negative, Advanced Breast Cancer Who Received no Prior Therapy for Advanced Disease(VICTORIANE) | terminated | Phase 3 | 98 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT02137837 | S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer | terminated | Phase 3 | 37 | SWOG Cancer Research NetworkNETWORK | 1 | Jan 28, 2021 | clinicaltrials |
| NCT03055312 | Bicalutamide in Treatment of Androgen Receptor (AR) Positive Metastatic Triple Negative Breast Cancer(SYSUCC-007) | terminated | Phase 3 | 36 | Sun Yat-sen UniversityOTHER | 1 | Jan 28, 2021 | clinicaltrials |
| NCT00448266 | Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD | terminated | Phase 2 / Phase 3 | 12 | The Netherlands Cancer InstituteOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT03327662 | Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer(CTC-STOP) | terminated | Phase 3 | 12 | Institute of Cancer Research, United KingdomOTHER | 1 | Jan 6, 2021 | clinicaltrials |
| NCT01827930 | Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response(MIM) | terminated | Phase 3 | 68 | Institut BergoniéOTHER | 1 | Dec 31, 2020 | clinicaltrials |
| NCT00662597 | ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer(ATRACT-1) | terminated | Phase 3 | 1,285 | Novartis PharmaceuticalsINDUSTRY | 26 | Dec 24, 2020 | clinicaltrials |
| NCT00738387 | A Study of ASA404 or Placebo in Combination With Docetaxel in Second-line Treatment for (Stage IIIb/IV) Non-small Cell Lung Cancer(ATTRACT-2) | terminated | Phase 3 | 900 | Novartis PharmaceuticalsINDUSTRY | 10 | Dec 24, 2020 | clinicaltrials |
| NCT00480025 | GSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Non-Small Cell Lung Cancer | terminated | Phase 3 | 2,278 | GlaxoSmithKlineINDUSTRY | 34 | Dec 22, 2020 | clinicaltrials |
| NCT03516084 | A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer | terminated | Phase 3 | 185 | Zai Lab (Shanghai) Co., Ltd.INDUSTRY | 1 | Dec 21, 2020 | clinicaltrials |
| NCT02951156 | Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL)(Javelin DLBCL) | terminated | Phase 3 | 29 | PfizerINDUSTRY | 8 | Dec 17, 2020 | clinicaltrials |
| NCT00058188 | Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation | terminated | Phase 3 | 53 | Northwestern UniversityOTHER | 1 | Dec 8, 2020 | clinicaltrials |
| NCT00023868 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | terminated | Phase 3 | — | American College of Radiology Imaging NetworkNETWORK | 1 | Dec 2, 2020 | clinicaltrials |
| NCT01687413 | Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer(ADEPT) | terminated | Phase 3 | 42 | Washington University School of MedicineOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT00269828 | A Survival Study for Women With Advanced Lung Cancer Who Have Not Previously Received Chemotherapy.(PIONEER) | terminated | Phase 3 | 600 | CTI BioPharmaINDUSTRY | 11 | Nov 24, 2020 | clinicaltrials |
| NCT01987596 | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer | terminated | Phase 3 | 23 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Oct 29, 2020 | clinicaltrials |
| NCT02425878 | Ulipristal Acetate 10 mg and Asisted Reproduction | terminated | Phase 3 | 2 | Instituto Valenciano de Infertilidad, IVI VALENCIAOTHER | 1 | Oct 14, 2020 | clinicaltrials |
| NCT00054184 | Polyglutamate Paclitaxel Compared With Docetaxel in Treating Patients With Progressive Non-Small Cell Lung Cancer | terminated | Phase 3 | 350 | CTI BioPharmaINDUSTRY | 1 | Oct 5, 2020 | clinicaltrials |
Data updated 24 days agoSource updated Sep 22, 2021source: clinicaltrials