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Neoplasm by Morphology
CI-CAN-00000002Explore in graph →
Non-malignant13,319 active trials222 approved drugs2,774 evidence items
- NCIt
- C4741
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Other
CI-CAN-00000002Explore in graph →
Genomics
449 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
230 cases with simple somatic mutation data · 586 cases total · 2026-01-07 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm | 108 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 230 |
| 47% |
| cbioportal |
| 2 | TP53 | Ssm | 106 | 230 | 46.1% | cbioportal |
| 3 | MUC16 | Ssm | 91 | 230 | 39.6% | cbioportal |
| 4 | RYR2 | Ssm | 82 | 230 | 35.7% | cbioportal |
| 5 | KRAS | Ssm | 75 | 230 | 32.6% | cbioportal |
| 6 | LRP1B | Ssm | 68 | 230 | 29.6% | cbioportal |
| 7 | USH2A | Ssm | 68 | 230 | 29.6% | cbioportal |
| 8 | ZFHX4 | Ssm | 63 | 230 | 27.4% | cbioportal |
| 9 | FLG | Ssm | 62 | 230 | 27% | cbioportal |
| 10 | SPTA1 | Ssm | 58 | 230 | 25.2% | cbioportal |
| 11 | MUC17 | Ssm | 48 | 230 | 20.9% | cbioportal |
| 12 | XIRP2 | Ssm | 47 | 230 | 20.4% | cbioportal |
| 13 | PCLO | Ssm | 46 | 230 | 20% | cbioportal |
| 14 | NAV3 | Ssm | 45 | 230 | 19.6% | cbioportal |
| 16 | FAT3 | Ssm | 44 | 230 | 19.1% | cbioportal |
| 15 | CSMD1 | Ssm | 44 | 230 | 19.1% | cbioportal |
| 17 | KMT2C | Ssm | 42 | 230 | 18.3% | cbioportal |
| 19 | ZNF536 | Ssm | 42 | 230 | 18.3% | cbioportal |
| 18 | PCDH15 | Ssm | 42 | 230 | 18.3% | cbioportal |
| 21 | KEAP1 | Ssm | 40 | 230 | 17.4% | cbioportal |
| 20 | COL11A1 | Ssm | 40 | 230 | 17.4% | cbioportal |
| 22 | STK11 | Ssm | 40 | 230 | 17.4% | cbioportal |
| 23 | ADGRG4 | Ssm | 39 | 230 | 17% | cbioportal |
| 24 | PAPPA2 | Ssm | 39 | 230 | 17% | cbioportal |
| 25 | RP1L1 | Ssm | 39 | 230 | 17% | cbioportal |
| 28 | APOB | Ssm | 38 | 230 | 16.5% | cbioportal |
| 29 | ZNF804A | Ssm | 38 | 230 | 16.5% | cbioportal |
| 27 | AHNAK2 | Ssm | 38 | 230 | 16.5% | cbioportal |
| 26 | ADAMTS12 | Ssm | 38 | 230 | 16.5% | cbioportal |
| 31 | FLG2 | Ssm | 37 | 230 | 16.1% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07