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Clinical trials
3,221 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (571)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06500091 | TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors | not yet recruiting | Phase 2 | 54 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jul 15, 2024 | clinicaltrials |
| NCT06008106 | Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma | recruiting | Phase 3 | 165 | Shanghai Kechow Pharma, Inc.INDUSTRY | 1 | Jun 28, 2024 |
| NCT03755739 | Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors | recruiting | Phase 2 / Phase 3 | 200 | Second Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Jun 25, 2024 | clinicaltrials |
| NCT06470880 | Circulating Tumour DNA Guided Adaptive BRAF and MEK Inhibitor Therapy(DyNAMIc) | not yet recruiting | Phase 2 | 40 | The Christie NHS Foundation TrustOTHER | 0 | Jun 24, 2024 | clinicaltrials |
| NCT05649683 | Immunological Functionnal Test Validation to Predict Melanoma Metastatic Patient Response to Checkpoint Inhibitors(mela-quantif) | recruiting | N/A | 60 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Jun 4, 2024 | clinicaltrials |
| NCT04309409 | Adjuvant Nivolumab Treatment in Stage II (IIA, IIB, IIC) High-risk Melanoma(NivoMela) | active not recruiting | Phase 3 | 374 | University Hospital, EssenOTHER | 1 | May 23, 2024 | clinicaltrials |
| NCT05539677 | Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research(REGATA) | recruiting | — | 1,000 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT03842943 | Neoadjuvant Combination Immunotherapy for Stage III Melanoma | recruiting | Phase 2 | 28 | University of LouisvilleOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT03685890 | Evaluating the Effect of Nivolumab for Patients With In-transit Metastases Treated With Isolated Limb Perfusion(NivoILP) | recruiting | Phase 1 / Phase 2 | 74 | Vastra Gotaland RegionOTHER_GOV | 2 | Apr 25, 2024 | clinicaltrials |
| NCT06327698 | Cadonilimab in Combination With Anlotinib in the Treatment of Locally Progressive or Metastatic Melanoma With First-Line Therapy Failure | not yet recruiting | Phase 2 | 30 | Hunan Cancer HospitalOTHER | 0 | Mar 25, 2024 | clinicaltrials |
| NCT06265025 | GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 125 | GeneMedicine Co., Ltd.INDUSTRY | 1 | Mar 21, 2024 | clinicaltrials |
| NCT05280314 | Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors | recruiting | Phase 2 | 60 | IO BiotechINDUSTRY | 6 | Mar 18, 2024 | clinicaltrials |
| NCT04949113 | Neoadjuvant Ipilimumab Plus Nivolumab Versus Standard Adjuvant Nivolumab in Macroscopic Stage III Melanoma(NADINA) | active not recruiting | Phase 3 | 423 | The Netherlands Cancer InstituteOTHER | 3 | Mar 8, 2024 | clinicaltrials |
| NCT06154668 | Profiling of Circulating Immune Cells to Uncover Response Signatures to Anti-PD1 Immunotherapy in Melanoma Patients(PHENOMENAL) | recruiting | — | 707 | University Hospital, GrenobleOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT04282044 | Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies | recruiting | Phase 1 | 60 | BioEclipse TherapeuticsINDUSTRY | 1 | Feb 8, 2024 | clinicaltrials |
| NCT06229340 | Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations(NТО-RAS) | recruiting | Phase 2 | 20 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | Jan 29, 2024 | clinicaltrials |
| NCT05746897 | A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 38 | Hefei TG ImmunoPharma Co., Ltd.OTHER | 1 | Jan 26, 2024 | clinicaltrials |
| NCT06212388 | Allogeneic Gammadelta T Cells Combined With Interferon-α1b or PD-1 Monoclonal Antibody in Stage III-IV Amenable to Surgical Resection Melanoma | not yet recruiting | Early Phase 1 | 10 | Xijing HospitalOTHER | 0 | Jan 25, 2024 | clinicaltrials |
| NCT05446155 | BioMEL- Diagnostic and Prognostic Factors in Melanoma.(BioMEL) | recruiting | — | 2,000 | Region SkaneOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT05022901 | An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma | active not recruiting | Phase 3 | 30 | Delcath Systems Inc.INDUSTRY | 1 | Dec 21, 2023 | clinicaltrials |
| NCT05029791 | Variations of Immune Infiltrate and Cell Plasticity Markers in Treated Metastatic Melanoma Patients(COLEMAN) | recruiting | N/A | 100 | Hospices Civils de LyonOTHER | 1 | Dec 15, 2023 | clinicaltrials |
| NCT05620290 | MRI-Guided Focused Ultrasound Radiosensitization for Patients With Malignant Melanoma and Non Melanoma Skin Cancer | recruiting | Phase 1 | 20 | Sunnybrook Health Sciences CentreOTHER | 1 | Dec 15, 2023 | clinicaltrials |
| NCT04729543 | MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck Cancer(MC2TCR) | recruiting | Phase 1 / Phase 2 | 20 | Erasmus Medical CenterOTHER | 1 | Dec 4, 2023 | clinicaltrials |
| NCT01942603 | Minimal SN Tumor Burden(Minitub) | active not recruiting | — | 296 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 10 | Nov 28, 2023 | clinicaltrials |
| NCT05270044 | Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation.(COLUMBUS-AD) | active not recruiting | Phase 3 | 815 | Pierre Fabre MedicamentINDUSTRY | 23 | Nov 22, 2023 | clinicaltrials |
| NCT06093594 | Investigating Participation Patterns Among Stage IV Melanoma Patients | not yet recruiting | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Oct 23, 2023 | clinicaltrials |
| NCT06028724 | A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)(POPCORN) | recruiting | — | 782 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Sep 13, 2023 | clinicaltrials |
| NCT05789043 | Camrelizumab in Combination With Apatinib and Temozolomide as First-line Treatment in Advanced Acral Melanoma | recruiting | Phase 3 | 140 | Peking University Cancer Hospital & InstituteOTHER | 1 | Sep 6, 2023 | clinicaltrials |
| NCT03563729 | Melanoma Metastasized to the Brain and Steroids(MEMBRAINS) | recruiting | Phase 2 | 80 | Inge Marie SvaneOTHER | 1 | Jul 13, 2023 | clinicaltrials |
| NCT05570227 | Metabolic Phenotypes in Melanoma(MetaMel) | recruiting | N/A | 240 | Peter MacCallum Cancer Centre, AustraliaOTHER | 1 | Jul 6, 2023 | clinicaltrials |
| NCT05253872 | The MELAcare Study: A New Method for Surveillance of Melanoma Patients | recruiting | N/A | 378 | Herlev and Gentofte HospitalOTHER | 1 | Jun 26, 2023 | clinicaltrials |
| NCT05733728 | Retrospective Register for Uveal Melanoma | recruiting | — | 1,400 | Medical University of ViennaOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT02068196 | A National Phase IV Study With Ipilimumab for Patients With Advanced Malignant Melanoma.(Ipi4) | active not recruiting | Phase 4 | 150 | Oslo University HospitalOTHER | 1 | Mar 24, 2023 | clinicaltrials |
| NCT05673681 | Spanish Academy of Dermatology and Venereology (AEDV) Melanoma Registry | recruiting | — | 7,000 | Fundación Academia Española de DermatologíaOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT03241186 | Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma | active not recruiting | Phase 2 | 36 | Robert R. McWilliams, MDOTHER | 1 | Dec 9, 2022 | clinicaltrials |
| NCT05539118 | Interferon-α1b Combined With Toripalimab and Anlotinib Hydrochloride in Advanced Unresectable Melanoma | not yet recruiting | Phase 1 / Phase 2 | 48 | Xijing HospitalOTHER | 1 | Sep 14, 2022 | clinicaltrials |
| NCT05527795 | Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma(Mel-ImmAdj) | recruiting | — | 1,000 | Hospices Civils de LyonOTHER | 1 | Sep 6, 2022 | clinicaltrials |
| NCT05366478 | A Clinical Study of LM103 Injection in the Treatment of Advanced Solid Tumors | recruiting | Phase 1 | 15 | Suzhou BlueHorse Therapeutics Co., Ltd.INDUSTRY | 1 | Aug 2, 2022 | clinicaltrials |
| NCT05037825 | The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors(PARADIGM) | recruiting | — | 800 | VastBiomeINDUSTRY | 1 | Apr 27, 2022 | clinicaltrials |
| NCT04550247 | A Prospective Non-Interventional Study in Participants Receiving Nivolumab in Adjuvant Setting for Resected Melanoma in Real-World Conditions in France(AdjuMel) | active not recruiting | — | 362 | Bristol-Myers SquibbINDUSTRY | 1 | Mar 21, 2022 | clinicaltrials |
| NCT01638676 | A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients | recruiting | Phase 1 / Phase 2 | 55 | University of LouisvilleOTHER | 1 | Oct 29, 2021 | clinicaltrials |
| NCT03787056 | Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients(ONCOPRO) | recruiting | N/A | 410 | Hospices Civils de LyonOTHER | 1 | Jul 16, 2021 | clinicaltrials |
| NCT04331093 | Neoadjuvant SHR-1210 Plus Apatinib for Resectable Stage III-IV Acral Melanoma | recruiting | Phase 2 | 40 | Di WuOTHER | 1 | May 26, 2021 | clinicaltrials |
| NCT04126876 | A Randomized Controlled Phase II Trial With Intradermal IMO-2125 in Pathological Tumor Stage (p) T3-4 cN0M0 Melanoma(INTRIM) | recruiting | Phase 2 | 214 | A.J.M. van den EertweghOTHER | 1 | Apr 15, 2021 | clinicaltrials |
| NCT04045691 | Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment(BERING) | recruiting | — | 750 | Pierre Fabre Pharma GmbHINDUSTRY | 3 | Jan 19, 2021 | clinicaltrials |
| NCT04622566 | Lenvatinib and Pembrolizumab in Resectable Mucosal Melanoma | not yet recruiting | Phase 2 | 26 | Peking University Cancer Hospital & InstituteOTHER | 1 | Nov 13, 2020 | clinicaltrials |
| NCT01586403 | Transfer of Genetically Engineered Lymphocytes in Melanoma Patients | active not recruiting | Phase 1 | 14 | Loyola UniversityOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT04493723 | Serial Tumour Biopsies and Blood Biomarkers in Melanoma | recruiting | — | 300 | The Christie NHS Foundation TrustOTHER | 1 | Jul 30, 2020 | clinicaltrials |
| NCT04477876 | Study of CD160, an Activating NK Cell Receptor, in Melanoma: a Potential Therapeutic Target?(NKCD160MEL) | not yet recruiting | — | 55 | Assistance Publique - Hôpitaux de ParisOTHER | 0 | Jul 20, 2020 | clinicaltrials |
| NCT02870244 | Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes | recruiting | Phase 1 | 18 | Loyola UniversityOTHER | 1 | Mar 12, 2018 | clinicaltrials |
Data updated 23 days agoSource updated Jul 15, 2024source: clinicaltrials