Cancer Family
Melanocytic Neoplasm
CI-CAN-00000026Explore in graph →
Non-malignant610 active trials13 approved drugs233 evidence items
- NCIt
- C7058
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Cancer Family
CI-CAN-00000026Explore in graph →
Clinical trials
3,258 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02583516 | Clinical Trial to Evaluate the Efficacy of Vemurafenib in Combination With Cobimetinib (Continuous and Intermittent) in BRAFV600-mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma | completed | Phase 2 | 70 | Grupo Español Multidisciplinar de MelanomaOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT01941927 | Trametinib With GSK2141795 in BRAF Wild-type Melanoma | completed | Phase 2 | 20 | Adil DaudOTHER | 1 | Feb 12, 2020 |
| NCT02608034 | A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State | completed | Phase 1 | 32 | Genentech, Inc.INDUSTRY | 4 | Feb 12, 2020 | clinicaltrials |
| NCT03052205 | A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors(ILLUMINATE-101) | completed | Phase 1 | 54 | Idera Pharmaceuticals, Inc.INDUSTRY | 2 | Feb 11, 2020 | clinicaltrials |
| NCT02451488 | Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma | completed | Phase 4 | 8 | Mayo ClinicOTHER | 1 | Feb 10, 2020 | clinicaltrials |
| NCT04253574 | Comparison of PET/CT and Ultrasound in Staging of Malignant Melanoma | completed | — | 258 | University of BaselOTHER | 0 | Feb 5, 2020 | clinicaltrials |
| NCT02537600 | Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis(CONVERCE) | completed | Phase 2 | 43 | Center Eugene MarquisOTHER | 1 | Jan 27, 2020 | clinicaltrials |
| NCT01065441 | Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer | completed | Phase 1 / Phase 2 | 9 | Michael Har-NoyINDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT02379195 | Peginterferon and TIL Therapy for Metastatic Melanoma | completed | Phase 1 / Phase 2 | 12 | Inge Marie SvaneOTHER | 1 | Jan 22, 2020 | clinicaltrials |
| NCT03159117 | Pfizer PF-06688992 in Patients With Stage III or Stage IV Melanoma | completed | Phase 1 | 7 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 22, 2020 | clinicaltrials |
| NCT02158520 | Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery | completed | Phase 2 | 24 | Academic and Community Cancer Research UnitedOTHER | 1 | Jan 21, 2020 | clinicaltrials |
| NCT01684241 | RBL001/RBL002 Phase I Clinical Trial(MERIT) | completed | Phase 1 | 29 | BioNTech RNA Pharmaceuticals GmbHINDUSTRY | 2 | Jan 18, 2020 | clinicaltrials |
| NCT02035956 | IVAC MUTANOME Phase I Clinical Trial | completed | Phase 1 | 15 | BioNTech RNA Pharmaceuticals GmbHINDUSTRY | 2 | Jan 18, 2020 | clinicaltrials |
| NCT02424916 | Adoptive Transfer of Specific Melanoma Antigens CD8+ T Cells in Metastatic Melanoma Patients: a Phase I/II Study(MelSort) | completed | Phase 1 / Phase 2 | 7 | Nantes University HospitalOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT02320305 | MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by Surgery | completed | Early Phase 1 | 23 | Mayo ClinicOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT01898585 | An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma | completed | Phase 4 | 60 | Hoffmann-La RocheINDUSTRY | 1 | Jan 7, 2020 | clinicaltrials |
| NCT02094872 | Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic | completed | Phase 2 | 49 | Yale UniversityOTHER | 1 | Jan 2, 2020 | clinicaltrials |
| NCT03628417 | Confirmatory Trial in the Evaluation of Ca Electroporation for the Treatment of Cutaneous Metastases | completed | N/A | 7 | Szeged UniversityOTHER | 0 | Jan 2, 2020 | clinicaltrials |
| NCT01962103 | Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors | completed | Phase 1 / Phase 2 | 107 | CelgeneINDUSTRY | 7 | Dec 27, 2019 | clinicaltrials |
| NCT02676869 | Phase 1 Study of IMP321 (Eftilagimod Alpha) Adjuvant to Anti-PD-1 Therapy in Unresectable or Metastatic Melanoma(TACTI-mel) | completed | Phase 1 | 24 | Immutep Australia Pty. Ltd.INDUSTRY | 1 | Dec 18, 2019 | clinicaltrials |
| NCT00145041 | Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction | completed | Phase 1 | 7 | Acrotech Biopharma Inc.INDUSTRY | 1 | Dec 12, 2019 | clinicaltrials |
| NCT00304460 | Mechanism of Action of High-Dose IL-2 (Aldesleukin) in Metastatic Melanoma and Kidney Cancer | completed | Phase 1 | 138 | National Cancer Institute (NCI)NIH | 1 | Dec 12, 2019 | clinicaltrials |
| NCT04180774 | Safety and Efficacy of Tag-7 Gene-modified Vaccine in Locally Advanced or Metastatic Malignant Melanoma or Kidney Cancer | completed | Phase 1 / Phase 2 | 80 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | Dec 6, 2019 | clinicaltrials |
| NCT02439411 | Retrospective Analysis of Dabrafenib +/- Trametinib Compassionate Use Experience in Spain(DEIS) | completed | — | 135 | Grupo Español Multidisciplinar de MelanomaOTHER | 1 | Dec 2, 2019 | clinicaltrials |
| NCT00590824 | Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma | completed | Phase 2 | 23 | University of Wisconsin, MadisonOTHER | 1 | Nov 21, 2019 | clinicaltrials |
| NCT02014441 | Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec | completed | Phase 2 | 61 | AmgenINDUSTRY | 2 | Nov 20, 2019 | clinicaltrials |
| NCT00003897 | Vaccine Therapy With gp100 and/or Sargramostim in Treating Patients With Malignant Melanoma | completed | Phase 1 | 18 | University of Wisconsin, MadisonOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT00109863 | Hu14.18-Interleukin-2 Fusion Protein in Treating Patients With Advanced Melanoma | completed | Phase 2 | 14 | University of Wisconsin, MadisonOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT01196416 | Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Combination With Cisplatin, Vinblastine, and Temozolomide in Treating Patients With Recurrent or Metastatic Melanoma | completed | Phase 1 / Phase 2 | 14 | National Cancer Institute (NCI)NIH | 1 | Nov 18, 2019 | clinicaltrials |
| NCT01136967 | An Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV Melanoma | completed | Phase 2 | 182 | Eisai Inc.INDUSTRY | 4 | Nov 13, 2019 | clinicaltrials |
| NCT00314093 | RFT-5-dgA in Patients With Metastatic Melanoma | completed | Phase 2 | 41 | University of Texas Southwestern Medical CenterOTHER | 1 | Nov 12, 2019 | clinicaltrials |
| NCT00057616 | Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma. | completed | Phase 3 | 274 | CelgeneINDUSTRY | 9 | Nov 8, 2019 | clinicaltrials |
| NCT01021059 | A Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer | completed | Phase 1 | 18 | National Cancer Institute (NCI)NIH | 1 | Nov 8, 2019 | clinicaltrials |
| NCT01883323 | Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With Melanoma | completed | Phase 2 | 12 | University Health Network, TorontoOTHER | 1 | Nov 8, 2019 | clinicaltrials |
| NCT00864253 | A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant Melanoma | completed | Phase 3 | 529 | CelgeneINDUSTRY | 9 | Oct 30, 2019 | clinicaltrials |
| NCT01551459 | A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma(SUAVE) | completed | Phase 2 | 124 | The Clatterbridge Cancer Centre NHS Foundation TrustOTHER | 1 | Oct 29, 2019 | clinicaltrials |
| NCT03165422 | A Real-World Study of Ipilimumab Treatment After Nivolumab Treatment in Melanoma in Japan | completed | — | 68 | Bristol-Myers SquibbINDUSTRY | 1 | Oct 23, 2019 | clinicaltrials |
| NCT00254397 | Melanoma Vaccine With Peptides and Leuprolide | completed | Phase 2 | 98 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 16, 2019 | clinicaltrials |
| NCT01213472 | Evaluation of a New Anti-cancer Immunotherapy in Patients With Non-operable and Progressing Metastatic Cutaneous Melanoma | completed | Phase 1 | 33 | GlaxoSmithKlineINDUSTRY | 8 | Oct 9, 2019 | clinicaltrials |
| NCT00839410 | Multicentric Cohort of Melanoma Patients in Ile de France Area(Melan-Cohort) | completed | — | 1,255 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Oct 4, 2019 | clinicaltrials |
| NCT02058953 | CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases(13-052) | completed | — | 7 | University of PittsburghOTHER | 2 | Oct 4, 2019 | clinicaltrials |
| NCT02374255 | Improving Goals of Care Discussion in Advanced Cancer Patients | completed | N/A | 265 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Oct 1, 2019 | clinicaltrials |
| NCT02387307 | A Study of rSIFN-co in Subjects With Advanced Solid Tumors(rSIFN-01) | completed | Phase 1 | 42 | Sichuan Huiyang Life Science and Technology CorporationINDUSTRY | 1 | Sep 27, 2019 | clinicaltrials |
| NCT02316795 | Fluorescence Imaging in Sentinel Lymph Node Biopsy for Breast Cancer and Melanoma | completed | Early Phase 1 | 20 | Washington University School of MedicineOTHER | 1 | Sep 24, 2019 | clinicaltrials |
| NCT00394134 | Targeted Intervention for Melanoma Prevention | completed | N/A | 205 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 13, 2019 | clinicaltrials |
| NCT03007823 | High-activity Natural Killer Immunotherapy for Small Metastases of Melanoma | completed | Phase 1 / Phase 2 | 20 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT00179764 | Immunoablative Mini Transplant (Hematopoietic Peripheral Blood Stem Cell Transplant [HPBSC]) | completed | N/A | 68 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Aug 30, 2019 | clinicaltrials |
| NCT02768207 | A Study to Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma | completed | Phase 2 | 40 | Hoffmann-La RocheINDUSTRY | 2 | Aug 28, 2019 | clinicaltrials |
Data updated 24 days agoSource updated Feb 17, 2020source: clinicaltrials