Hematologic Malignancy
Mature B-Cell Non-Hodgkin Lymphoma
CI-CAN-00003259Explore in graph →
Hematologic792 active trials17 approved drugs43 evidence items
- NCIt
- C7056
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Hematologic Malignancy
CI-CAN-00003259Explore in graph →
Clinical trials
2,506 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (393)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04566887 | Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma | active not recruiting | Phase 2 | 105 | University Health Network, TorontoOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT05776160 | Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Axicabtagene Ciloleucel | available | — | — | Kite, A Gilead CompanyINDUSTRY | 2 | Jun 12, 2026 | clinicaltrials |
| NCT06703892 | A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies(CD20/19 CAR T) | recruiting | Phase 1 | 18 | GenomeFrontier Therapeutics TW Co., Ltd.INDUSTRY | 1 | Jun 12, 2026 | clinicaltrials |
| NCT03622788 | Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant | active not recruiting | Phase 1 / Phase 2 | 16 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 11, 2026 | clinicaltrials |
| NCT05978739 | Evaluating Different Doses of Orelabrutinib in MCL | completed | Phase 2 | 40 | InnoCare Pharma Inc.INDUSTRY | 1 | Jun 11, 2026 | clinicaltrials |
| NCT06985576 | Long-term Study to Evaluate Safety and Persistence of GF-CART01 | enrolling by invitation | — | 18 | GenomeFrontier Therapeutics TW Co., Ltd.INDUSTRY | 1 | Jun 11, 2026 | clinicaltrials |
| NCT07220187 | Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial | not yet recruiting | Phase 3 | 102 | SWOG Cancer Research NetworkNETWORK | 0 | Jun 11, 2026 | clinicaltrials |
| NCT02242097 | Ibrutinib After Intensive Induction in Treating Patients With Previously Untreated Mantle Cell Lymphoma | completed | Phase 2 | 37 | Northwestern UniversityOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT04833114 | Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) Versus R-ICE Alone in Second Line Treatment of Diffuse Large B-cell Lymphoma (DLBCL)(Pola-R-ICE) | completed | Phase 3 | 306 | GWT-TUD GmbHOTHER | 4 | Jun 10, 2026 | clinicaltrials |
| NCT04844866 | Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients(DALY 2-EU) | recruiting | Phase 2 | 213 | Miltenyi Biomedicine GmbHINDUSTRY | 14 | Jun 10, 2026 | clinicaltrials |
| NCT05025423 | Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma | terminated | Phase 2 | 7 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT06594640 | R-CMOP in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma | recruiting | Phase 1 / Phase 2 | 108 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT07637929 | Non-Interventional Study of Puzol-cel for CD19-Positive Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia | not yet recruiting | — | 200 | Chongqing Precision Biotech Co., LtdINDUSTRY | 0 | Jun 10, 2026 | clinicaltrials |
| NCT07638982 | Axatilimab + CAR-T for High-Risk Lymphoma | not yet recruiting | Phase 1 | 29 | Northside Hospital, Inc.OTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT04892277 | CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies | recruiting | Phase 1 | 25 | Mayo ClinicOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT05658562 | A Study of MT-2111 in Patients With Relapsed/Refractory DLBCL | active not recruiting | Phase 1 / Phase 2 | 46 | Tanabe Pharma CorporationINDUSTRY | 1 | Jun 9, 2026 | clinicaltrials |
| NCT07555470 | Mosunetuzumab and Zeprumetostat in Treating Patients With Follicular Lymphoma(CUREFL03) | recruiting | Phase 2 | 80 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT01661881 | Rituximab/Bendamustine + Rituximab/Cytarabine for Mantle Cell Lymphoma | active not recruiting | Phase 2 | 23 | Christine RyanOTHER | 1 | Jun 8, 2026 | clinicaltrials |
| NCT03494179 | A Study to Evaluate ICP-022 in Patients With R/R Mantle Cell Lymphoma (MCL) | completed | Phase 1 / Phase 2 | 106 | Beijing InnoCare Pharma Tech Co., Ltd.INDUSTRY | 1 | Jun 8, 2026 | clinicaltrials |
| NCT03960840 | Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL | active not recruiting | Phase 1 / Phase 2 | 217 | Novartis PharmaceuticalsINDUSTRY | 8 | Jun 4, 2026 | clinicaltrials |
| NCT04722172 | A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL | active not recruiting | Phase 2 | 55 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT04974216 | Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older | active not recruiting | Phase 2 | 71 | The Lymphoma Academic Research OrganisationOTHER | 2 | Jun 4, 2026 | clinicaltrials |
| NCT06131801 | Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution | recruiting | — | 30 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT06271057 | Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse | recruiting | Phase 2 | 65 | The Lymphoma Academic Research OrganisationOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT06948786 | Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL Trial | recruiting | Phase 2 | 22 | University of WashingtonOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07168980 | Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents(B-NHL) | recruiting | Phase 2 / Phase 3 | 87 | Children's Cancer Group, ChinaNETWORK | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07528352 | External Beam Radiotherapy Followed by Bispecific Antibody Therapy for Relapsed/Refractory DLBCL(REBEL) | recruiting | Phase 1 | 12 | University of UtahOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT01415752 | Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma | active not recruiting | Phase 2 | 373 | Eastern Cooperative Oncology GroupNETWORK | 2 | Jun 3, 2026 | clinicaltrials |
| NCT04054167 | Ultra Low Dose Radiation Delivered Before or After Chemotherapy-Free Targeted Therapy in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma | active not recruiting | Phase 2 | 51 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT06224309 | Preliminary Assessment of [18F]BL40 in PET/CT Scans | completed | — | 10 | British Columbia Cancer AgencyOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT01046825 | Mature B-Cell Lymphoma And Leukemia Study III | active not recruiting | Phase 2 / Phase 3 | 128 | St. Jude Children's Research HospitalOTHER | 3 | Jun 2, 2026 | clinicaltrials |
| NCT02972840 | A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL | active not recruiting | Phase 3 | 635 | Acerta Pharma BVINDUSTRY | 27 | Jun 1, 2026 | clinicaltrials |
| NCT04139304 | A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma | recruiting | Early Phase 1 | 15 | AIDS Malignancy ConsortiumNETWORK | 1 | Jun 1, 2026 | clinicaltrials |
| NCT04600804 | The Role of 18F-FDG-PET for Staging and Prognostication | completed | — | 200 | Fondazione Italiana Linfomi - ETSOTHER | 2 | Jun 1, 2026 | clinicaltrials |
| NCT04739813 | Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma | active not recruiting | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05162170 | Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study | completed | — | 633 | Fondazione Italiana Linfomi - ETSOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05412290 | Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma | active not recruiting | Phase 1 | 9 | Washington University School of MedicineOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05663502 | Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers | recruiting | — | 200 | AIDS Malignancy ConsortiumNETWORK | 1 | Jun 1, 2026 | clinicaltrials |
| NCT04195633 | Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies | recruiting | Phase 2 | 60 | Fred Hutchinson Cancer CenterOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT05418088 | Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies | recruiting | Phase 1 | 54 | Sumithira VasuOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT05734495 | Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia | active not recruiting | Phase 2 | 46 | Dana-Farber Cancer InstituteOTHER | 1 | May 28, 2026 | clinicaltrials |
| NCT01351896 | Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | active not recruiting | Phase 2 | 49 | National Cancer Institute (NCI)NIH | 1 | May 27, 2026 | clinicaltrials |
| NCT02159755 | Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma | active not recruiting | Phase 1 | 28 | National Cancer Institute (NCI)NIH | 1 | May 27, 2026 | clinicaltrials |
| NCT06458439 | Epcoritamab-CAR T Cells for Large B-cell Lymphomas | recruiting | Phase 2 | 31 | Abramson Cancer Center at Penn MedicineOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07608978 | Efficacy and Safety of Polatuzumab Vedotin in Combination With Zanubrutinib, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma of the MCD/BN2/N1 Subtypes(Pola-ZRCHP) | recruiting | Phase 2 | 35 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07609355 | AI-Assisted Optimization of Online Adaptive Radiotherapy for Gastric Lymphoma(GLORIA) | not yet recruiting | N/A | 25 | Sun Yat-sen UniversityOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07609446 | Pomalidomide Plus Anti-CD20 Antibody and Prednisone in Frontline Indolent B-Cell Lymphoma | not yet recruiting | — | 30 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT03598998 | Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas | active not recruiting | Phase 1 / Phase 2 | 13 | City of Hope Medical CenterOTHER | 1 | May 26, 2026 | clinicaltrials |
| NCT03820817 | Rifaximin in Patients With Monoclonal Gammopathy | completed | Phase 1 | 50 | Emory UniversityOTHER | 1 | May 26, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jun 12, 2026source: clinicaltrials