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CancerIndexthe global index of cancer

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CancerIndex

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Mature B-Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Hematopoietic and Lymphoid Cell Neoplasm
Lymphocytic Neoplasm
B-Cell Neoplasm
Mature B-Cell Neoplasm

Hematologic Malignancy

Mature B-Cell Neoplasm

CI-CAN-00003258Explore in graph →

HematologicNon-malignant1,787 active trials44 approved drugs119 evidence items

NCIt: C27910
DOID: 706

Overview
Statistics
Survival
Genomics20
Variants & evidence119
Drugs23
Trials6664
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (211)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 151–175 of 211 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia.
· JAMA Oncol · 2015 · PMID 26182309 · validated civic_curation pubmed
The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia.
· Clin Cancer Res · 2006 · PMID 17020971 · validated civic_curation pubmed
BTKC481S-Mediated Resistance to Ibrutinib in Chronic Lymphocytic Leukemia.
· J Clin Oncol · 2017 · PMID 28418267 · validated civic_curation pubmed
Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan.
· Cancer Sci · 2021 · PMID 34159682 · validated civic_curation pubmed
EZH2 mutations are frequent and represent an early event in follicular lymphoma.
· Blood · 2013 · PMID 24052547 · validated civic_curation pubmed
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.
· Blood · 2011 · PMID 21487109 · validated civic_curation pubmed
Distinct molecular profile of IRF4-rearranged large B-cell lymphoma.
· Blood · 2020 · PMID 31738823 · validated civic_curation pubmed

Showing 151–175 of 211 publications

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Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways.

· Proc Natl Acad Sci U S A · 2008 · PMID 18765795 · validated civic_curation pubmed

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.

· Nature · 2011 · PMID 21796119 · validated civic_curation pubmed

Targeting the BRAF V600E mutation in multiple myeloma.

· Cancer Discov · 2013 · PMID 23612012 · validated civic_curation pubmed

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.

· Blood · 2012 · PMID 22210878 · validated civic_curation pubmed

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

· J Exp Med · 2011 · PMID 21670202 · validated civic_curation pubmed

p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression.

· Blood · 1993 · PMID 8241511 · validated civic_curation pubmed

Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial.

· J Clin Oncol · 2011 · PMID 21483000 · validated civic_curation pubmed

Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia.

· Cancer Res · 1998 · PMID 9788599 · validated civic_curation pubmed

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.

· Blood · 2016 · PMID 27226433 · validated civic_curation pubmed

ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression.

· Haematologica · 2012 · PMID 21993670 · validated civic_curation pubmed

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma.

· Nat Med · 2015 · PMID 26193344 · validated civic_curation pubmed

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.

· Blood · 2015 · PMID 25452615 · validated civic_curation pubmed

Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma.

· Blood Adv · 2020 · PMID 32589730 · validated civic_curation pubmed

Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact.

· Blood · 2019 · PMID 30602617 · validated civic_curation pubmed

Experience with provisional WHO-entities large B-cell lymphoma with IRF4-rearrangement and Burkitt-like lymphoma with 11q aberration in paediatric patients of the NHL-BFM group.

· Br J Haematol · 2020 · PMID 32239695 · validated civic_curation pubmed

Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions.

· Blood · 2004 · PMID 14726385 · validated civic_curation pubmed

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma.

· Blood · 2012 · PMID 22383795 · validated civic_curation pubmed

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia.

· N Engl J Med · 2015 · PMID 26352686 · validated civic_curation pubmed