Subtype
Malignant Urinary Tract Neoplasm
CI-CAN-00003252Explore in graph →
507 active trials14 approved drugs29 evidence items
- NCIt
- C192668
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Subtype
CI-CAN-00003252Explore in graph →
Clinical trials
1,954 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (246)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07525349 | Immune-Stromal Landscape in Muscle-Invasive Bladder Cancer | not yet recruiting | — | 100 | Assiut UniversityOTHER | 0 | Apr 13, 2026 | clinicaltrials |
| NCT07526792 | SYS6002 vs Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma | not yet recruiting | Phase 3 | 406 | CSPC Megalith Biopharmaceutical Co.,Ltd.INDUSTRY | 0 | Apr 13, 2026 | clinicaltrials |
| NCT07503795 | Outcomes of Definitive Radiotherapy for Bladder Cancer | not yet recruiting | — | 300 | Sohag UniversityOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT07468838 | Feasibility Study of Urinary cfDNA Analysis as a Non-invasive Monitoring Tool in Patients With Prostate or Bladder Cancer(UroDNA) | not yet recruiting | — | 25 | Institut Cancerologie de l'OuestOTHER | 0 | Mar 16, 2026 | clinicaltrials |
| NCT07460245 | Maintenance AVElumab After SECond Line Platinum-based Chemotherapy for Metastatic Urothelial Carcinoma(AVESEC) | not yet recruiting | Phase 2 | 144 | Gruppo Oncologico Italiano di Ricerca ClinicaOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT07445308 | The Study is to Evaluate the Safety and Tolerability of SPGL008 Alone or in Combination With BCG in the Patients With NMIBC, and to Determine the RP2D of SPGL008 Alone or in Combination With BCG.To Evaluate the Preliminary Efficacy of SPGL008 Alone or in Combination With BCG. | not yet recruiting | Phase 1 / Phase 2 | 120 | Shenyang Sunshine Pharmaceutical Co., LTD.INDUSTRY | 0 | Mar 3, 2026 | clinicaltrials |
| NCT07412171 | NECTAR Study: Neoadjuvant Toripalimab + 9MW2821 for Local UTUC(NECTAR) | not yet recruiting | Phase 2 | 40 | Peking University Third HospitalOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07374549 | SYS6002 vs PADCEV in Patients With Advanced Urothelial Carcinoma | not yet recruiting | Phase 2 | 100 | CSPC Megalith Biopharmaceutical Co.,Ltd.INDUSTRY | 0 | Jan 29, 2026 | clinicaltrials |
| NCT07346053 | The Impact of Time-of-day Administration of EV/P on Objective Response Rate in Adults With Advanced Bladder Cancer(Chrono-EVP) | not yet recruiting | Phase 3 | 224 | Guliz OzgunOTHER | 1 | Jan 16, 2026 | clinicaltrials |
| NCT07279597 | A Phase II Study of Toripalimab Plus RC48-ADC With Radiotherapy for Bladder Preservation in HER2-Positive Muscle-Invasive Bladder Cancer | not yet recruiting | Phase 2 | 45 | Tongji HospitalOTHER | 0 | Dec 19, 2025 | clinicaltrials |
| NCT07043543 | Evaluation of the Clinical Utility of Online Adaptive Radiotherapy in Bladder Cancer (BLADAPT-GETUG V11)(BLADAPT) | not yet recruiting | N/A | 120 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT07261592 | Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer | not yet recruiting | Phase 1 / Phase 2 | 29 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT07257718 | The Combined Role of FAPI PET and Liquid Biopsy in the Staging and Clinical Management of Bladder Cancer - FUTURE Trial(FUTURE) | not yet recruiting | Phase 2 | 262 | Chiti ArturoOTHER | 0 | Dec 2, 2025 | clinicaltrials |
| NCT06829823 | Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder Cancer | not yet recruiting | Phase 2 | 20 | ImmunityBio, Inc.INDUSTRY | 0 | Oct 16, 2025 | clinicaltrials |
| NCT07204301 | Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study(Flexi-comfort) | not yet recruiting | N/A | 378 | Western University, CanadaOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT07204496 | A Clinical Study on the Safety, Tolerance, and Preliminary Efficacy of γδ-T Cell Injection in the Treatment of Advanced Bladder Cancer(γδ-T-BLADDER) | not yet recruiting | — | 20 | Shanghai 10th People's HospitalOTHER | 0 | Oct 2, 2025 | clinicaltrials |
| NCT06727214 | Survival Benefits of Neoadjuvant Systemic Chemotherapy in Muscle Invasive Bladder Cancer(AssiutU) | not yet recruiting | — | 87 | Sara Mahmoud Ahmed MahmoudOTHER | 0 | Sep 30, 2025 | clinicaltrials |
| NCT07184021 | Neoadjuvent Dose-dense Gemcitabine and Cisplatin In Muscle Invasive Bladder Cancer(No Acronym) | not yet recruiting | Phase 2 | 30 | Assiut UniversityOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT07125924 | Intravesical Hyaluronic Acid (HA) for Preventing Radiation Cystitis on Bladder Cancer | not yet recruiting | N/A | 54 | National Cancer Center, KoreaOTHER_GOV | 1 | Aug 15, 2025 | clinicaltrials |
| NCT07064863 | A Tumor Immune Biomarker Guided Approach for Improving Response to BCG in Patients With High-risk NMIBC.(BCG-TIME) | not yet recruiting | Phase 1 / Phase 2 | 31 | Queen's UniversityOTHER | 1 | Jul 17, 2025 | clinicaltrials |
| NCT06994078 | Clinical Application of PET Imaging Targeting Nectin-4 in Malignant Tumors | not yet recruiting | N/A | 56 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT06982690 | Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial | not yet recruiting | N/A | 370 | National Taiwan University HospitalOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT06957561 | Disitamab Vedotin Combined With Ivonescimab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer(DIVON) | not yet recruiting | Phase 1 / Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06912672 | Performance Evaluation of a Urine-based Methylation Assay for Urothelial Carcinoma(UMT-UC) | not yet recruiting | — | 1,500 | Shanghai Epiprobe Biotechnology Co., Ltd.INDUSTRY | 0 | Apr 8, 2025 | clinicaltrials |
| NCT06364904 | A Clinical Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma. | not yet recruiting | Phase 3 | 210 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Feb 21, 2025 | clinicaltrials |
| NCT06798246 | HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively:A Perspective Cohort Study | not yet recruiting | — | 200 | Peking University First HospitalOTHER | 0 | Jan 29, 2025 | clinicaltrials |
| NCT06762925 | Study on the Efficacy and Mechanism of METTL3 Peptide Inhibitors in Enhancing Anti-tumor Immune Response by Reshaping the Tumor Microenvironment | not yet recruiting | — | 450 | Xijing HospitalOTHER | 0 | Jan 8, 2025 | clinicaltrials |
| NCT06751667 | Xpert Bladder Monitor: a Non-Invasive Follow-Up Tool for Detecting Relapse in High Grade or High Risk Bladder Cancer(LIBERO) | not yet recruiting | N/A | 50 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 0 | Dec 30, 2024 | clinicaltrials |
| NCT06694649 | Better in Better Out Cystectomy.(BIBOCYS-1) | not yet recruiting | — | 100 | Ziekenhuis Oost-LimburgOTHER | 0 | Nov 19, 2024 | clinicaltrials |
| NCT06675656 | Predictive Role of Microbiome in Patients With Urothelial Carcinoma | not yet recruiting | — | 420 | IRCCS San RaffaeleOTHER | 0 | Nov 5, 2024 | clinicaltrials |
| NCT06630871 | A Clinical Trial Evaluating the Efficacy and Safety of Disitamab Vedotin Plus Tislelizumab Combined with Re-TURBT in the Treatment of HER-2-high Expression(2+-3+) Non-muscle Invasive Bladder Cancer At High-risk and Very High-risk. | not yet recruiting | Phase 2 | 40 | Fujian Medical University Union HospitalOTHER | 1 | Oct 10, 2024 | clinicaltrials |
| NCT06588179 | SHR-1501 Combined With SHR-2005 for High-Risk Non-Muscle Invasive Bladder Cancer Which is Not Completely Resectable by TURBt | not yet recruiting | Phase 1 / Phase 2 | 58 | Fudan UniversityOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06551896 | Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor | not yet recruiting | Phase 2 | 30 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 0 | Aug 13, 2024 | clinicaltrials |
| NCT06548438 | The Impact of PDD During TURB for NMIBC(TUR_BLUE) | not yet recruiting | Phase 4 | 300 | A.O.U. Città della Salute e della ScienzaOTHER | 0 | Aug 12, 2024 | clinicaltrials |
| NCT06528483 | Bladder Preservation With Sacituzumab Govitecan + Zimberelimab for Muscle-Invasive Bladder Cancer(preSAVE) | not yet recruiting | Phase 2 | 63 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Jul 30, 2024 | clinicaltrials |
| NCT06310369 | Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer | not yet recruiting | Phase 2 | 50 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | Jul 22, 2024 | clinicaltrials |
| NCT06469229 | Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria | not yet recruiting | — | 1,200 | Changhai HospitalOTHER | 1 | Jul 5, 2024 | clinicaltrials |
| NCT06472752 | Neoadjuvant Radiotherapy for High-risk UTUC(LUXUS07) | not yet recruiting | — | 40 | Peking University First HospitalOTHER | 1 | Jun 25, 2024 | clinicaltrials |
| NCT06355518 | Pre-operative Immuno-Nutrition in Radical Cystectomy(INu-RC) | not yet recruiting | N/A | 260 | Fondazione IRCCS Policlinico San Matteo di PaviaOTHER | 1 | Apr 9, 2024 | clinicaltrials |
| NCT06325423 | Predicting Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer | not yet recruiting | — | 50 | Assiut UniversityOTHER | 0 | Mar 26, 2024 | clinicaltrials |
| NCT06255964 | A Study of IAP0971 in Combination With Bacillus Calmette Guerin in High Risk Non-muscular Invasive Bladder Cancer | not yet recruiting | Phase 1 / Phase 2 | 236 | SUNHO(China)BioPharmaceutical CO., Ltd.INDUSTRY | 0 | Feb 13, 2024 | clinicaltrials |
| NCT06009510 | Exploring Engagement Dynamics Among Individuals Impacted by Bladder Cancer | not yet recruiting | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Aug 24, 2023 | clinicaltrials |
| NCT05810623 | Single-Dose Intravesical Chemotherapy After Diagnostic URS(MINERVA) | not yet recruiting | Phase 3 | 394 | David D'AndreaOTHER | 1 | Apr 12, 2023 | clinicaltrials |
| NCT04167332 | Prospective Collection of Samples for Urothelial Cancer of Bladder(ProCSUCaB) | not yet recruiting | — | 630 | Universitaire Ziekenhuizen KU LeuvenOTHER | 0 | Nov 18, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Apr 13, 2026source: clinicaltrials