Cancer Family
Malignant Thoracic Neoplasm
CI-CAN-00000256Explore in graph →
2,775 active trials51 approved drugs626 evidence items
- NCIt
- C3576
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Cancer Family
CI-CAN-00000256Explore in graph →
Clinical trials
11,501 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,528)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02711345 | A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers. | terminated | Phase 1 | 65 | Novartis PharmaceuticalsINDUSTRY | 6 | Sep 19, 2019 | clinicaltrials |
| NCT02187367 | Safety & Efficacy Study of EGF Cancer Vaccine to Treat Stage IV Biomarker Positive, Wild Type EGF-R NSCLC Patients(EGF) | terminated | Phase 3 | 106 | Bioven EuropeINDUSTRY | 11 | Sep 10, 2019 |
| NCT02937402 | Bronchoscopy With Bronchoalveolar Lavage in Identifying Biomarkers of Response to Immune Checkpoint Inhibitors in Patients With Non-small Cell or Small Cell Lung Cancer | terminated | N/A | 9 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Sep 10, 2019 | clinicaltrials |
| NCT02132884 | Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer | terminated | N/A | 1 | Fox Chase Cancer CenterOTHER | 1 | Sep 4, 2019 | clinicaltrials |
| NCT03479294 | Real-World Study on Adjuvant Therapy Combined With Shenlingcao Oral Liquid in Patients for Stage II and IIIA Non-small Cell Lung Cancer After Radical Resection | terminated | — | 9 | West China HospitalOTHER | 1 | Aug 26, 2019 | clinicaltrials |
| NCT02054819 | Treating NSCLC Minimal Stage IV With Curative Intent | terminated | Phase 2 | 14 | Leo W. Jenkins Cancer CenterOTHER | 1 | Aug 21, 2019 | clinicaltrials |
| NCT01374100 | Effect of Qigong Therapy in Patients With Advanced Lung and Gastrointestinal Cancer Undergoing Chemotherapy | terminated | N/A | 52 | McGill UniversityOTHER | 1 | Aug 16, 2019 | clinicaltrials |
| NCT02200354 | The Safety and Efficacy of Pemetrexed Rechallenge With Bevacizumab | terminated | Phase 2 | 20 | Kobe City General HospitalOTHER | 1 | Aug 14, 2019 | clinicaltrials |
| NCT03785808 | Reducing Insulin, Growth Hormones, and Tumors(RIGHT) | terminated | N/A | 3 | Fred Hutchinson Cancer CenterOTHER | 1 | Aug 12, 2019 | clinicaltrials |
| NCT01822496 | Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer | terminated | Phase 2 | 59 | National Cancer Institute (NCI)NIH | 1 | Aug 5, 2019 | clinicaltrials |
| NCT02109016 | A Study to Assess the Efficacy and Safety of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With Advanced/Metastatic Lung Cancer and FGF, VEGF, or PDGF Related Genetic Alterations | terminated | Phase 2 | 18 | Clovis Oncology, Inc.INDUSTRY | 5 | Jul 29, 2019 | clinicaltrials |
| NCT01646125 | An Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations | terminated | Phase 2 | 59 | Novartis PharmaceuticalsINDUSTRY | 12 | Jul 24, 2019 | clinicaltrials |
| NCT02952989 | A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors | terminated | Phase 1 | 47 | Seagen Inc.INDUSTRY | 1 | Jul 19, 2019 | clinicaltrials |
| NCT02431169 | Genomic Landscape of EGFR Mutant NSCLC Prior to Erlotinib and at the Time of Disease Progression | terminated | — | 5 | Washington University School of MedicineOTHER | 1 | Jul 18, 2019 | clinicaltrials |
| NCT02713828 | Study of Glembatumumab Vedotin in gpNMB-Expressing, Advanced or Metastatic SCC of the Lung(PrE0504) | terminated | Phase 1 / Phase 2 | 13 | PrECOG, LLC.OTHER | 1 | Jul 16, 2019 | clinicaltrials |
| NCT02630186 | A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC | terminated | Phase 1 / Phase 2 | 3 | Clovis Oncology, Inc.INDUSTRY | 1 | Jul 5, 2019 | clinicaltrials |
| NCT02005614 | A Pilot/Phase II Study of Gamma Knife Radiosurgery for Brain Metastases Using 3Tesla MRI and Rational Dose Selection | terminated | N/A | 39 | Yale UniversityOTHER | 1 | Jul 1, 2019 | clinicaltrials |
| NCT02367352 | Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumors | terminated | Phase 1 | 9 | Millennium Pharmaceuticals, Inc.INDUSTRY | 2 | Jun 26, 2019 | clinicaltrials |
| NCT00714246 | Bortezomib (PS-341) in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer | terminated | Phase 1 | 6 | Milton S. Hershey Medical CenterOTHER | 1 | Jun 24, 2019 | clinicaltrials |
| NCT00685750 | Expression Analysis of Specific Markers in Non-small Cell Lung Cancer or Melanoma | terminated | N/A | 88 | GlaxoSmithKlineINDUSTRY | 5 | Jun 20, 2019 | clinicaltrials |
| NCT03348904 | Nivolumab and Epacadostat With Platinum Doublet Chemotherapy Versus Platinum Doublet Chemotherapy in Non-Small Cell Lung Cancer | terminated | Phase 3 | 2 | Incyte CorporationINDUSTRY | 1 | Jun 13, 2019 | clinicaltrials |
| NCT02410382 | Dexamethasone for Treatment of Radiation-related Fatigue in Patients Receiving RT for Head-neck and Lung Cancer | terminated | Phase 2 | 79 | University of ArizonaOTHER | 1 | May 14, 2019 | clinicaltrials |
| NCT02186301 | TIGER-1: Safety and Efficacy Study of Rociletinib (CO-1686) or Erlotinib in Patients With EGFR-mutant/Metastatic NSCLC Who Have Not Had Any Previous EGFR Directed Therapy(EGFR) | terminated | Phase 2 / Phase 3 | 100 | Clovis Oncology, Inc.INDUSTRY | 7 | May 7, 2019 | clinicaltrials |
| NCT02080078 | A Phase I Dose Escalation Study of Erlotinib in Combination With Theophylline | terminated | Phase 1 | 15 | AHS Cancer Control AlbertaOTHER | 1 | May 3, 2019 | clinicaltrials |
| NCT00568906 | Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma | terminated | — | 129 | Stanford UniversityOTHER | 1 | May 2, 2019 | clinicaltrials |
| NCT02271906 | The ATTAIN Study: A Therapeutic Trial of Afatinib In the Neoadjuvant Setting | terminated | Phase 2 | 2 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 30, 2019 | clinicaltrials |
| NCT02775006 | Docetaxel Versus Intercalated Erlotinib-docetaxel in Patients With Relapsed EGFR Wild Type, ALK Negative Non Squamous Cell Carcinoma | terminated | Phase 3 | 45 | The Netherlands Cancer InstituteOTHER | 1 | Apr 30, 2019 | clinicaltrials |
| NCT00793208 | Immunization of Patients With Non Small Cell Lung Cancer (NSCLC) | terminated | Phase 1 | 1 | Theresa Whiteside, PhDOTHER | 1 | Apr 12, 2019 | clinicaltrials |
| NCT02556593 | IMRT Combined With Erlotinib for EGFR Wild Type Non-small Cell Lung Cancer With 4-10 Brain Metastases | terminated | Phase 2 | 12 | Sun Yat-sen UniversityOTHER | 1 | Apr 12, 2019 | clinicaltrials |
| NCT03175172 | Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM) | terminated | Phase 2 | 10 | Aduro Biotech, Inc.INDUSTRY | 1 | Apr 4, 2019 | clinicaltrials |
| NCT00459121 | Vandetanib, Carboplatin, and Paclitaxel in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Can Be Removed by Surgery | terminated | Phase 2 | 2 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Mar 26, 2019 | clinicaltrials |
| NCT02751385 | Investigation of the Effect of Nintedanib on the Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Patients With Non-small Cell Lung Cancer | terminated | Phase 1 | 2 | Boehringer IngelheimINDUSTRY | 1 | Mar 14, 2019 | clinicaltrials |
| NCT01445054 | 111 Indium CHX-A DTPA Trastuzumab (Indium-Herceptin) for Imaging Breast Cancer | terminated | Early Phase 1 | 13 | National Cancer Institute (NCI)NIH | 1 | Mar 11, 2019 | clinicaltrials |
| NCT03220100 | Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOL | terminated | N/A | 11 | Massachusetts General HospitalOTHER | 1 | Mar 8, 2019 | clinicaltrials |
| NCT00153842 | A Study of Paclitaxel and Carboplatin in Combination With Bexarotene Oral Capsules in Patients With Advanced Lung Cancer | terminated | Phase 1 / Phase 2 | 33 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Mar 6, 2019 | clinicaltrials |
| NCT00754923 | Sorafenib in Treating Non-Smokers or Former Light Smokers With Relapsed or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer | terminated | Phase 2 | 11 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 6, 2019 | clinicaltrials |
| NCT03172988 | Dexamethasone, Flurbiprofen Axetil and Long-term Survival After Lung Cancer Surgery | terminated | Phase 4 | 126 | Peking University First HospitalOTHER | 1 | Mar 5, 2019 | clinicaltrials |
| NCT02846792 | Nivolumab and Plinabulin in Treating Patients With Stage IIIB-IV, Recurrent, or Metastatic Non-small Cell Lung Cancer | terminated | Phase 1 / Phase 2 | 5 | University of WashingtonOTHER | 1 | Mar 4, 2019 | clinicaltrials |
| NCT02483416 | Evaluation of the Impact of Nurse-led Telephone on Treatment Compliance | terminated | — | 30 | Boehringer IngelheimINDUSTRY | 1 | Mar 1, 2019 | clinicaltrials |
| NCT02883790 | Effects of Somnage® in the Management on Sleep and Mood in Cancer Patients | terminated | N/A | 3 | Helsinn Healthcare SAINDUSTRY | 1 | Feb 22, 2019 | clinicaltrials |
| NCT00969306 | Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patients(Chloroquine IV) | terminated | Phase 1 | 5 | Maastricht Radiation OncologyOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT01210378 | Nitroglycerin in Non-small Cell Lung Cancer(Nitroglycerin) | terminated | Phase 2 | 47 | Maastricht Radiation OncologyOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT02409355 | A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower111) | terminated | Phase 3 | 8 | Hoffmann-La RocheINDUSTRY | 14 | Feb 15, 2019 | clinicaltrials |
| NCT00465907 | Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer | terminated | Phase 2 | 7 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Feb 11, 2019 | clinicaltrials |
| NCT02346370 | A Phase 1b Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined With Docetaxel in Subjects With Recurrent Previously Treated Locally Advanced or Metastatic NSCLC(PRIMAL) | terminated | Phase 1 | 16 | Halozyme TherapeuticsINDUSTRY | 1 | Feb 8, 2019 | clinicaltrials |
| NCT01011439 | Phase II Study Of Oral PHA-848125AC In Patients With Thymic Carcinoma | terminated | Phase 2 | 72 | Tiziana Life Sciences LTDINDUSTRY | 3 | Feb 6, 2019 | clinicaltrials |
| NCT01301391 | Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of Chemotherapy | terminated | Phase 2 | 30 | Tiziana Life Sciences LTDINDUSTRY | 2 | Feb 6, 2019 | clinicaltrials |
| NCT01115803 | A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors | terminated | Phase 1 | 29 | Eli Lilly and CompanyINDUSTRY | 2 | Feb 5, 2019 | clinicaltrials |
| NCT01207726 | Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery | terminated | Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Feb 5, 2019 | clinicaltrials |
Data updated 24 days agoSource updated Sep 19, 2019source: clinicaltrials