Cancer Family
Malignant Nervous System Neoplasm
CI-CAN-00000246Explore in graph →
953 active trials7 approved drugs131 evidence items
- NCIt
- C4788
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000246Explore in graph →
Clinical trials
3,457 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (495)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04967690 | A Dose Escalation Study to Estimate MTD, DLTs and Pharmacokinetics After a Single Intracranial Dose of SI-053 as an add-on to the Current Standard of Care, in Adult Patients With Newly Diagnosed GBM(TARGLIO) | unknown | Phase 1 | 27 | Double Bond Pharmaceutical ABINDUSTRY | 0 | Jul 6, 2023 | clinicaltrials |
| NCT05929456 | Multispectral Bimodal Fluorescence Guided Surgery of High-grade Glioma With Cetuximab-800CW and 5-ALA (5-aminolevulinic Acid)(MIRROR) | unknown | Phase 1 | 21 | University Medical Center Groningen |
| 1 |
| Jul 3, 2023 |
| clinicaltrials |
| NCT04671459 | TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine(TaRRGET) | unknown | Phase 2 | 40 | Prof. Franciszek Lukaszczyk Memorial Oncology CenterOTHER | 1 | Jun 28, 2023 | clinicaltrials |
| NCT05918432 | Determining Patterns In Study Experiences of Neuroblastoma Patients | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 1 | Jun 26, 2023 | clinicaltrials |
| NCT05191784 | GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients | unknown | Phase 2 | 20 | Genexine, Inc.INDUSTRY | 1 | Jun 12, 2023 | clinicaltrials |
| NCT05728125 | Pinpointing the Factors Affecting Clinical Trial Experiences of Glioblastoma Patients | unknown | — | 500 | Power Life Sciences Inc.INDUSTRY | 0 | Jun 12, 2023 | clinicaltrials |
| NCT04223999 | Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)(OptimalTTF-2) | unknown | Phase 2 | 70 | Anders Rosendal KorshøjOTHER | 1 | Jun 6, 2023 | clinicaltrials |
| NCT03411408 | Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.(HBO-RT) | unknown | N/A | 24 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | May 30, 2023 | clinicaltrials |
| NCT05764460 | Social Cognition and Language in Patients With Gliomas | unknown | — | 105 | University Medical Center GroningenOTHER | 0 | May 17, 2023 | clinicaltrials |
| NCT05816746 | Decitabine and Anti-PD-1 in R/R DLBCL | unknown | Phase 2 | 20 | Chinese PLA General HospitalOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT05850377 | 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas | unknown | — | 90 | Sociedad de Lucha Contra el Cáncer del EcuadorOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT02137759 | MRSI to Predict Response to RT/TMZ ± Belinostat in GBM | unknown | Phase 2 | 29 | Emory UniversityOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05781919 | Use of Virtual Reality for Surgical Planning in Neuroblastoma(VRNB) | unknown | N/A | 130 | Hospital Sant Joan de DeuOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT04700514 | Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study | unknown | N/A | 60 | Seoul National University HospitalOTHER | 1 | Apr 24, 2023 | clinicaltrials |
| NCT04359745 | Improving Treatment of Glioblastoma: Distinguishing Progression From Pseudoprogression | unknown | — | 500 | Guy's and St Thomas' NHS Foundation TrustOTHER | 1 | Apr 21, 2023 | clinicaltrials |
| NCT05170087 | Radiomic Analysis for Predicting Treatment Response and Clinical Outcomes in Malignancies | unknown | — | 1,200 | Sunnybrook Health Sciences CentreOTHER | 1 | Apr 19, 2023 | clinicaltrials |
| NCT05363826 | Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac® | unknown | Phase 1 | 30 | Photolitec LLCINDUSTRY | 1 | Apr 13, 2023 | clinicaltrials |
| NCT05811793 | Efficacy and Safety of SCAI of Bevacizumab Combined With IC of Tislelizumab in the Treatment of Recurrent Glioblastoma. | unknown | N/A | 36 | Second Affiliated Hospital of Nanchang UniversityOTHER | 0 | Apr 13, 2023 | clinicaltrials |
| NCT05793021 | FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype | unknown | N/A | 70 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 31, 2023 | clinicaltrials |
| NCT01672463 | Clinical Trial of IV OKN-007 in a Pilot Cohort of Human Recurrent Malignant Glioma Patients(OKN-007) | unknown | Phase 1 | 31 | Oblato, Inc.INDUSTRY | 1 | Mar 29, 2023 | clinicaltrials |
| NCT03561207 | 3D Prediction of Patient-Specific Response(3D-PREDICT) | unknown | — | 570 | KIYATECINDUSTRY | 1 | Mar 24, 2023 | clinicaltrials |
| NCT05782959 | Phase 1 Study of BCD-245 in Subjects With Neuroblastoma | unknown | Phase 1 | 24 | BiocadINDUSTRY | 1 | Mar 24, 2023 | clinicaltrials |
| NCT05772741 | Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs(2253) | unknown | N/A | 160 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 16, 2023 | clinicaltrials |
| NCT05737368 | Treatment of Recurrent Glioblastoma With Fractionated Radiotherapy Combined With Cadonilimab | unknown | Phase 1 | 11 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 21, 2023 | clinicaltrials |
| NCT03561259 | A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects(OPTIMUM) | unknown | Phase 2 | 60 | Jubilant DraxImage Inc.INDUSTRY | 1 | Feb 16, 2023 | clinicaltrials |
| NCT04642937 | Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma | unknown | Phase 1 | 24 | OX2 TherapeuticsINDUSTRY | 1 | Jan 27, 2023 | clinicaltrials |
| NCT05700955 | Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastoma | unknown | Phase 1 | 30 | University of LouisvilleOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT05694416 | Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma | unknown | Phase 2 | 60 | Zhongnan HospitalOTHER | 0 | Jan 23, 2023 | clinicaltrials |
| NCT04840069 | Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma | unknown | Phase 2 | 100 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT04717739 | TIGER PRO-Active - Daily Activity, Sleep and Neurocognitive Functioning Study | unknown | — | 500 | NovoCure Ltd.INDUSTRY | 1 | Jan 10, 2023 | clinicaltrials |
| NCT05540873 | A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I) | unknown | Phase 1 | 18 | CellabMEDINDUSTRY | 1 | Jan 6, 2023 | clinicaltrials |
| NCT04077866 | B7-H3 CAR-T for Recurrent or Refractory Glioblastoma | unknown | Phase 1 / Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT04385173 | Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma | unknown | Phase 1 | 12 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05667402 | Clinical Study of TBF Regimen in Allo-HSCT in Patients With CNS Leukemia | unknown | N/A | 50 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Dec 28, 2022 | clinicaltrials |
| NCT05663125 | LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas | unknown | Phase 1 / Phase 2 | 10 | Beijing Tiantan HospitalOTHER | 1 | Dec 23, 2022 | clinicaltrials |
| NCT05656300 | Glioblastoma Imaging Using a Strong Iron-like Bloodpool Contrast Medium? | unknown | — | 15 | Radboud University Medical CenterOTHER | 0 | Dec 19, 2022 | clinicaltrials |
| NCT05624736 | Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning | unknown | — | 500 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Nov 22, 2022 | clinicaltrials |
| NCT04481815 | Rituximab Plus Methotrexate With or Without Lenalidomide in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma | unknown | Phase 2 | 240 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Nov 8, 2022 | clinicaltrials |
| NCT05600491 | A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme | unknown | Phase 3 | 78 | Sun Yat-sen UniversityOTHER | 1 | Oct 31, 2022 | clinicaltrials |
| NCT05135858 | Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma(METHOGLU) | unknown | Phase 1 | 18 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Oct 25, 2022 | clinicaltrials |
| NCT05589961 | Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme | unknown | Early Phase 1 | 10 | The Second Hospital of Hebei Medical UniversityOTHER | 1 | Oct 21, 2022 | clinicaltrials |
| NCT03750071 | VXM01 Plus Avelumab Combination Study in Progressive Glioblastoma | unknown | Phase 1 / Phase 2 | 30 | Vaximm GmbHINDUSTRY | 1 | Oct 20, 2022 | clinicaltrials |
| NCT04438044 | A Study to Evaluate ICP-022 in Patients With R/R PCNSL and SCNSL | unknown | Phase 2 | 61 | Beijing InnoCare Pharma Tech Co., Ltd.INDUSTRY | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05095441 | A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma | unknown | Phase 1 | 51 | ImmVira Pharma Co. LtdINDUSTRY | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05557240 | Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients | unknown | N/A | 10 | Shanghai 10th People's HospitalOTHER | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05556382 | Glioblastoma Evaluation for Heterogeneity In RadioseNsitivity(GEHIRN) | unknown | — | 30 | Istituto Clinico HumanitasOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT05305885 | Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis | unknown | N/A | 100 | The First Hospital of Jilin UniversityOTHER | 1 | Sep 30, 2022 | clinicaltrials |
| NCT05515133 | Correlation Between Psychological Stress and Disease Progression in Newly Diagnosed Glioblastoma Patients | unknown | — | 60 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
| NCT05539339 | Personalized Trial in ctDNA-level-relapse Glioblastoma | unknown | N/A | 20 | Henan Provincial People's HospitalOTHER | 1 | Sep 27, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Jul 6, 2023source: clinicaltrials