Subtype
Malignant Neoplasm of Unknown Primary
CI-CAN-00001150CUPExplore in graph →
4,163 active trials54 approved drugs532 evidence items
- NCIt
- C8566
- Other
- 1 more code
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Subtype
CI-CAN-00001150CUPExplore in graph →
Clinical trials
14,260 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,895)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03829722 | Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer | completed | Phase 2 | 26 | University of Michigan Rogel Cancer CenterOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT03978689 | A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma | completed | Phase 1 | 80 | Cue BiopharmaINDUSTRY | 1 | Jan 22, 2026 | clinicaltrials |
| NCT05641896 | Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers(18F-FAPI-74 GI) | completed | Phase 2 | 109 | SOFIEINDUSTRY | 1 | Jan 22, 2026 | clinicaltrials |
| NCT05746195 | Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) | completed | N/A | 46 | University of California, San FranciscoOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT02826928 | Diagnostic Performances of Urine and Plasma 5-hydroxyindolacetic Acid (5HIAA) Values in Patients With Small-intestine Neuroendocrine Tumors | completed | N/A | 116 | CHU de ReimsOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT03377491 | Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3) | completed | Phase 3 | 571 | NovoCure Ltd.INDUSTRY | 20 | Jan 21, 2026 | clinicaltrials |
| NCT03503344 | Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer(PILLAR) | completed | Phase 2 | 26 | University of California, San FranciscoOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT03578406 | HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer | completed | Phase 1 | 9 | Xinqiao Hospital of ChongqingOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT03889912 | Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma | completed | Phase 1 | 97 | Regeneron PharmaceuticalsINDUSTRY | 3 | Jan 21, 2026 | clinicaltrials |
| NCT04505553 | Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer | completed | Phase 2 | 78 | University of WashingtonOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT05524025 | The SPOT-HPV Study | completed | — | 360 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT06388304 | THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence(THRIVE) | completed | N/A | 39 | Joanna ArchOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT06426927 | PeLear CCC: Proyecto Latino Contra Cancer Colorrectal(PeLear CCC) | completed | N/A | 60 | University of North Carolina, Chapel HillOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT03575793 | A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer | completed | Phase 1 / Phase 2 | 39 | Salma SabbourOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT04139057 | EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC | completed | Phase 1 / Phase 2 | 10 | Xinqiao Hospital of ChongqingOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT07349576 | Precision Dietary Intervention Improves Postoperative Energy Intake, Nutritional Status, and Recovery in Patients Undergoing Hepatectomy for Liver Cancer: A Randomized Controlled Trial | completed | N/A | 139 | Anhui Provincial HospitalOTHER_GOV | 1 | Jan 20, 2026 | clinicaltrials |
| NCT05001971 | Anlotinib Plus Penpulimab as Second-line Treatment for Patients With Small Cell Lung Cancer After Failure of Platinum-based Chemotherapy | completed | Phase 2 | 65 | Hunan Cancer HospitalOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT05349331 | Watch and Wait and Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma(WATCH) | completed | Phase 2 | 74 | Sun Yat-sen UniversityOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT07340437 | Clinical Study of 18F-Exendin-4 in Insulinoma | completed | — | 20 | Sichuan Provincial People's HospitalOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT04362436 | TheraSphere Selective Internal Radiation Therapy (SIRT) as Treatment for Neuroendocrine Tumours With Liver Mets(ArTisaN) | completed | Phase 2 | 24 | Imperial College LondonOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT06840548 | A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer(OncoCAIX) | completed | Phase 1 | 20 | Philogen S.p.A.INDUSTRY | 1 | Jan 13, 2026 | clinicaltrials |
| NCT07337122 | Collagen Matrix in Oral Cancer Surgery | completed | — | 33 | SAYAH CharlineOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT05337137 | A Study of Nivolumab and Relatlimab in Combination With Bevacizumab in Advanced Liver Cancer(RELATIVITY-106) | completed | Phase 1 / Phase 2 | 83 | Bristol-Myers SquibbINDUSTRY | 15 | Jan 12, 2026 | clinicaltrials |
| NCT07329920 | Mesenchymal CTC Ratio Dynamics Predicts Response and Survival in Pancreatic Ductal Adenocarcinoma With Neoadjuvant/Conversion Therapy | completed | — | 300 | Guo ShiWeiOTHER | 1 | Jan 12, 2026 | clinicaltrials |
| NCT04870515 | Diet and Physical Activity Intervention for the Prevention of ADT-Induced Metabolic Changes in Patients With Prostate Cancer, TRIPLE-A PILOT Study | completed | N/A | 20 | Fred Hutchinson Cancer CenterOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT04326257 | Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy | completed | Phase 2 | 20 | Dan ZandbergOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT04459468 | Identify Proteomic Biomarkers for Outcome Prediction of Locoregional Treatments for HCC | completed | — | 17 | University of Texas Southwestern Medical CenterOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT04567615 | A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors | completed | Phase 2 | 266 | Bristol-Myers SquibbINDUSTRY | 17 | Jan 8, 2026 | clinicaltrials |
| NCT02324647 | Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield(SERENDIPITY) | completed | — | 807 | University Medical Center GroningenOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT06760234 | Multimodal Deep Learning Model Predicts Pancreatic Cancer Prognosis | completed | — | 247 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07321613 | Effect of TCC Cocktail Combined With TACE Versus TACE Alone on Survival in uHCC Patients | completed | — | 545 | Shanghai Zhongshan HospitalOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT05482880 | Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region | completed | — | 78 | Maastricht University Medical CenterOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT06839378 | Flura-seq for Evaluating the Effects of Different Hyperthermic Intraperitoneal Chemotherapy Regimens on the Transcriptome of Pseudomyxoma Peritonei | completed | N/A | 36 | Beijing Tsinghua Chang Gung HospitalOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT07316309 | CXCR4 PET/CT for Predicting Outcome in Limited-Stage Small Cell Lung Cancer | completed | — | 33 | Shandong Cancer Hospital and InstituteOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT07317713 | A Two-decade Mortality Risk Analysis of Gastrointestinal Carcinoid Neoplasms: an Updated SEER-based Study 2000-2022 | completed | — | 93,481 | Suez Canal UniversityOTHER | 0 | Jan 5, 2026 | clinicaltrials |
| NCT07317726 | Recent Trends in Stage Migration of Gastrointestnial Carcinoid Tumors Over Two Decades: a Retrospective SEER-based Analysis 2000-2022 | completed | — | 93,481 | Suez Canal UniversityOTHER | 0 | Jan 5, 2026 | clinicaltrials |
| NCT03199274 | Perflutren Protein-Type A Microspheres and Contrast-Enhanced Ultrasound in Improving Response to Radioembolization Therapy in Patients With Liver Cancer | completed | Phase 2 | 104 | Thomas Jefferson UniversityOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT03896412 | Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma(PERSO-NECK) | completed | N/A | 40 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT04031534 | Study of Hypoxia Measured in F-Miso PET/Scan and MRI in Patients With Squamous Cells Carcinoma(HYPONECK) | completed | Phase 2 | 16 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT02131805 | Electronic Skin Surface Brachytherapy for Cutaneous Basal Cell and Squamous Cell Carcinoma | completed | N/A | 36 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT03345420 | Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer(NOVEMBER) | completed | Phase 2 | 102 | University of UtahOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT04490564 | Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma | completed | — | 135 | Pharmassist LtdINDUSTRY | 1 | Dec 30, 2025 | clinicaltrials |
| NCT05100082 | Survey of Cabozantinib Tablets Used To Treat People With Hepatocellular Carcinoma | completed | — | 263 | TakedaINDUSTRY | 1 | Dec 30, 2025 | clinicaltrials |
| NCT01827956 | Role of FCγRIIIA and FCγRIIA Receptor Polymorphisms(FCR-VADS) | completed | — | 121 | Institut BergoniéOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT04045496 | A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors | completed | Phase 1 | 40 | Jacobio Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Dec 29, 2025 | clinicaltrials |
| NCT04148911 | A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer(EL1SSAR) | completed | Phase 3 | 184 | Hoffmann-La RocheINDUSTRY | 13 | Dec 26, 2025 | clinicaltrials |
| NCT01618643 | Aceto-whitening in the Assessment of Gastrointestinal Neoplasia | completed | — | 197 | Portsmouth Hospitals NHS TrustOTHER_GOV | 1 | Dec 24, 2025 | clinicaltrials |
| NCT01658878 | An Immuno-therapy Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab or Nivolumab in Combination With Other Agents in Patients With Advanced Liver Cancer(CheckMate040) | completed | Phase 1 / Phase 2 | 657 | Bristol-Myers SquibbINDUSTRY | 13 | Dec 24, 2025 | clinicaltrials |
| NCT03246516 | Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers(DELOGAST) | completed | N/A | 258 | University Hospital, LilleOTHER | 1 | Dec 23, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jan 22, 2026source: clinicaltrials