Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03608046 | Avelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer(AVETUXIRI) | unknown | Phase 2 | 59 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT04593446 | Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery | unknown | Phase 2 | 414 | National Cancer Center, Korea |
| 1 |
| Oct 20, 2020 |
| clinicaltrials |
| NCT04527068 | QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer(BEVTOR) | unknown | Phase 2 | 50 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Sep 17, 2020 | clinicaltrials |
| NCT02226289 | Bevacizumab-containing Regimen for Metastatic Colorectal Cancer Failed to Cytotoxic Treatment(BATTLE) | unknown | Phase 2 | 46 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT04126655 | Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate | unknown | Phase 1 / Phase 2 | 30 | Vastra Gotaland RegionOTHER_GOV | 1 | Aug 27, 2020 | clinicaltrials |
| NCT04499586 | A Study of Radiotherapy Combined With Raltitrexed and Irinotecan in Metastatic or Locally Recurrent Colorectal Cancer | unknown | Phase 2 | 30 | Fudan UniversityOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT04337879 | A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 56 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jul 21, 2020 | clinicaltrials |
| NCT04476641 | A Study of DC-CIK Immunotherapy in the Treatment of Solid Tumors(DC-CIK) | unknown | Phase 2 | 686 | Sun Yat-sen UniversityOTHER | 1 | Jul 20, 2020 | clinicaltrials |
| NCT04475159 | Combined Neoadjuvant Systemic and PIPAC Therapy (NASPIT) for Patients With Colorectal Peritoneal Metastasis Eligible for CRS and HIPEC: A Prospective Phase II Trial | unknown | Phase 2 | 50 | Prof. Aviram NissanOTHER_GOV | 0 | Jul 17, 2020 | clinicaltrials |
| NCT04340401 | Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen | unknown | Phase 2 | 25 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 9, 2020 | clinicaltrials |
| NCT04446091 | A Clinical Study of Exploring Camrelizumab in the Treatment of Colorectal Mucinous Adenocarcinoma(MAC) | unknown | Phase 1 / Phase 2 | 40 | Zhejiang Cancer HospitalOTHER | 1 | Jun 24, 2020 | clinicaltrials |
| NCT04411524 | The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer | unknown | Phase 2 | 50 | Fudan UniversityOTHER | 1 | Jun 2, 2020 | clinicaltrials |
| NCT04411537 | The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer | unknown | Phase 2 | 50 | Fudan UniversityOTHER | 1 | Jun 2, 2020 | clinicaltrials |
| NCT04394598 | A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer | unknown | Phase 2 | 210 | Fudan UniversityOTHER | 1 | May 19, 2020 | clinicaltrials |
| NCT04389151 | Triplezumab Combined With CAPEOX Regimen in Neoadjuvant Therapy for Locally Advanced Colon Cancer | unknown | Phase 2 | 30 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT03946917 | JS001 Combined With Regorafenib in Patients With Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Sun Yat-sen UniversityOTHER | 1 | May 12, 2020 | clinicaltrials |
| NCT04380103 | A Phase I/II Study of XELOXIRI and Bevacizumab as First-line Treatment in Metastatic Colorectal Cancer | unknown | Phase 1 / Phase 2 | 106 | Chinese Academy of Medical SciencesOTHER | 1 | May 8, 2020 | clinicaltrials |
| NCT02887313 | FOLFOX6 Totally Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer: A Real World Study(FOTAC) | unknown | Phase 2 | 200 | Sun Yat-sen UniversityOTHER | 1 | May 4, 2020 | clinicaltrials |
| NCT03397199 | Study of Apatinib Plus S-1 as the Therapy of Advanced Colorectal Cancer | unknown | Phase 2 | 120 | Henan Cancer HospitalOTHER_GOV | 1 | Apr 15, 2020 | clinicaltrials |
| NCT03150706 | Avelumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer | unknown | Phase 2 | 33 | Asan Medical CenterOTHER | 1 | Apr 3, 2020 | clinicaltrials |
| NCT02161822 | Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients | unknown | Phase 2 | 60 | Samsung Medical CenterOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT04298320 | A Trial of SHR-1210 in Combination With AIN457 in Patients With MSS CRC（SHR-1210-AIN457） | unknown | Phase 1 / Phase 2 | 40 | Yanqiao ZhangOTHER | 0 | Mar 16, 2020 | clinicaltrials |
| NCT04296240 | Induction Chemotherapy for MRF-negative, Moderate-risk, Resectable Middle and Low Rectal Cancer | unknown | Phase 2 | 119 | Peking University Cancer Hospital & InstituteOTHER | 1 | Mar 5, 2020 | clinicaltrials |
| NCT04294953 | Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery | unknown | Phase 2 | 60 | Assiut UniversityOTHER | 0 | Mar 4, 2020 | clinicaltrials |
| NCT04268290 | Single Incision Plus One Port Laparoscopic Surgery Assistant Enhanced Recovery After Surgery on Colorectal Cancer | unknown | Phase 2 | 120 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Feb 13, 2020 | clinicaltrials |
| NCT03022734 | Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis | unknown | Phase 2 | 40 | Yonsei UniversityOTHER | 1 | Jan 13, 2020 | clinicaltrials |
| NCT03638206 | Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies | unknown | Phase 1 / Phase 2 | 73 | Shenzhen BinDeBio Ltd.INDUSTRY | 1 | Dec 11, 2019 | clinicaltrials |
| NCT04188158 | Analysis of the Effectiveness of Neoadjuvant Chemotherapy in the Treatment of Colon Cancer Locally Advanced (ELECLA)(ELECLA) | unknown | Phase 2 | 238 | Universidad de LeónOTHER | 1 | Dec 5, 2019 | clinicaltrials |
| NCT04170530 | Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer | unknown | Phase 2 | 51 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Nov 20, 2019 | clinicaltrials |
| NCT04160416 | mXELOXIRI Combined With Molecular Targeted Drug in mCRC(TRICAP) | unknown | Phase 2 | 48 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT04097444 | CAPOXIRI+Bevacizumab vs. FOLFOXIRI+Bevacizumab for mCRC(QUATTRO-II) | unknown | Phase 2 | 112 | Chugai PharmaceuticalINDUSTRY | 1 | Oct 31, 2019 | clinicaltrials |
| NCT04118933 | A Study for PD-1 Antibody JS001 in MSI-H Advanced or Recurrent Colorectal Cancer | unknown | Phase 2 | 40 | Xu jianminOTHER | 1 | Oct 8, 2019 | clinicaltrials |
| NCT01923987 | Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis | unknown | Phase 2 | 39 | Korea Cancer Center HospitalOTHER | 1 | Sep 20, 2019 | clinicaltrials |
| NCT02331927 | PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer(PERMAD) | unknown | Phase 2 | 150 | University of UlmOTHER | 1 | Sep 20, 2019 | clinicaltrials |
| NCT03699332 | Multi-modality Imaging in Peritoneal Carcinomatosis of Colorectal Origin(MMIPC) | unknown | Phase 1 / Phase 2 | 29 | Radboud University Medical CenterOTHER | 1 | Sep 13, 2019 | clinicaltrials |
| NCT01802645 | Cetuximab/FOLFIRI With or Without Oxaliplatin and FOLFOXIRI With or Without Bevacizumab in Neoadjuvant Treatment of Non-resectable Colorectal Liver Metastases(CELIM2) | unknown | Phase 2 | 91 | Technische Universität DresdenOTHER | 1 | Sep 11, 2019 | clinicaltrials |
| NCT03813641 | RALOX or CAPOX + Bevacizumab in the First-line Treatment of Advanced CRC(ROCB Study) | unknown | Phase 2 | 100 | Shenzhen People's HospitalOTHER | 1 | Sep 9, 2019 | clinicaltrials |
| NCT04035096 | The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients | unknown | Phase 1 / Phase 2 | 40 | National Taiwan University HospitalOTHER | 1 | Jul 29, 2019 | clinicaltrials |
| NCT03944252 | Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)(CARACAS) | unknown | Phase 2 | 54 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Jul 26, 2019 | clinicaltrials |
| NCT03185988 | Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System | unknown | Phase 2 | 100 | Shen LinOTHER | 1 | Jul 19, 2019 | clinicaltrials |
| NCT04008511 | Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal Cancer | unknown | Phase 1 / Phase 2 | 54 | China Medical University, ChinaOTHER | 1 | Jul 5, 2019 | clinicaltrials |
| NCT01047969 | Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy | unknown | Phase 2 | 99 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 13, 2019 | clinicaltrials |
| NCT00647530 | Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery(FOxTROT) | unknown | Phase 2 / Phase 3 | 1,053 | University of BirminghamOTHER | 1 | May 17, 2019 | clinicaltrials |
| NCT03927898 | Phase II Study of Toripalimab Plus Stereotactic Body Radiotherapy in Colorectal Cancer Patients With Oligometastasis | unknown | Phase 2 | 40 | Chinese Academy of Medical SciencesOTHER | 1 | Apr 25, 2019 | clinicaltrials |
| NCT03912857 | Camrelizumab(SHR-1210) Combined With Apatinib in the Treatment of Advanced Metastatic Colorectal Cancer | unknown | Phase 2 | 50 | Sun Yat-sen UniversityOTHER | 1 | Apr 16, 2019 | clinicaltrials |
| NCT03904537 | A Study of Combination of Anti-PD1 Antibody-activated TILs and Chemotherapy in Colorectal Cancer | unknown | Phase 1 / Phase 2 | 20 | Sun Yat-sen UniversityOTHER | 1 | Apr 5, 2019 | clinicaltrials |
| NCT03880877 | Regorafenib Plus FOLFIRI With Irinotecan Dose Escalated in Patients With Previously Treated Metastatic Colorectal Cancer | unknown | Phase 2 | 153 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 1 | Mar 21, 2019 | clinicaltrials |
| NCT03711240 | The Efficacy of Bevacizumab Combined With m-FOLFOXIRI in Borderline Resectable Colorectal Liver Metastases(CBL) | unknown | Phase 2 | 40 | National Cheng-Kung University HospitalOTHER | 1 | Mar 13, 2019 | clinicaltrials |
| NCT02624726 | Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment(MINOAS) | unknown | Phase 2 | 31 | Hellenic Oncology Research GroupOTHER | 1 | Feb 22, 2019 | clinicaltrials |
| NCT03329183 | High-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28 | unknown | Phase 2 | 90 | Shanghai Changzheng HospitalOTHER | 1 | Feb 15, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Oct 22, 2020source: clinicaltrials