Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT01729923 | A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer(ADAPT) | terminated | Phase 2 | 27 | University of WashingtonOTHER | 1 |
| Jan 16, 2018 |
| clinicaltrials |
| NCT00226941 | A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer | terminated | Phase 1 / Phase 2 | 23 | George Albert FisherOTHER | 1 | Dec 8, 2017 | clinicaltrials |
| NCT00903396 | Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer | terminated | Phase 2 | 7 | Alliance for Clinical Trials in OncologyOTHER | 1 | Nov 24, 2017 | clinicaltrials |
| NCT00625183 | Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma | terminated | Phase 2 | 5 | Roswell Park Cancer InstituteOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT01606124 | Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer | terminated | Phase 2 | 39 | Mayo ClinicOTHER | 1 | Oct 27, 2017 | clinicaltrials |
| NCT00003485 | Antineoplaston Therapy in Treating Patients With Metastatic or Unresectable Colon Cancer | terminated | Phase 2 | 15 | Burzynski Research InstituteOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT00449163 | Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer | terminated | Phase 2 | 25 | University of MiamiOTHER | 1 | May 11, 2017 | clinicaltrials |
| NCT02277093 | Pacritinib to Inhibit JAK/STAT Signaling in Refractory Colorectal Cancer | terminated | Phase 2 | 11 | Washington University School of MedicineOTHER | 1 | May 1, 2017 | clinicaltrials |
| NCT00126451 | A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED) | terminated | Phase 2 | 16 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Apr 10, 2017 | clinicaltrials |
| NCT00588900 | Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab | terminated | Phase 2 | 5 | Alliance for Clinical Trials in OncologyOTHER | 1 | Apr 5, 2017 | clinicaltrials |
| NCT00127036 | Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A) | terminated | Phase 2 | 65 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 23, 2017 | clinicaltrials |
| NCT00361244 | SU011248 in Combination With Irinotecan and Cetuximab as a Second Line Regimen for Stage IV Colorectal Cancer | terminated | Phase 1 / Phase 2 | 6 | Massachusetts General HospitalOTHER | 1 | Feb 17, 2017 | clinicaltrials |
| NCT00276861 | Gemcitabine and Oxaliplatin as Second-Line Therapy in Treating Patients With Metastatic Colon Cancer | terminated | Phase 2 | 10 | University of MiamiOTHER | 1 | Feb 8, 2017 | clinicaltrials |
| NCT01718808 | Cetuximab for Elderly Patients With mCRC | terminated | Phase 2 | 24 | Swiss Cancer InstituteOTHER | 1 | Jan 24, 2017 | clinicaltrials |
| NCT00537823 | Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement | terminated | Phase 2 | 9 | Washington University School of MedicineOTHER | 1 | Dec 20, 2016 | clinicaltrials |
| NCT00081224 | Neoadjuvant Celecoxib and Capecitabine Combined With Pelvic Irradiation in Treating Patients With Stage II or Stage III Adenocarcinoma (Cancer) of the Rectum | terminated | Phase 2 | 3 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 15, 2016 | clinicaltrials |
| NCT02045030 | Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer | terminated | Phase 2 | 14 | CR-CSSS Champlain-Charles-Le MoyneOTHER | 1 | Nov 16, 2016 | clinicaltrials |
| NCT01060423 | TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer(DEBIRITUX) | terminated | Phase 2 | 8 | Hans-Joachim Schmoll, MDOTHER | 1 | Oct 26, 2016 | clinicaltrials |
| NCT01085331 | MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC) | terminated | Phase 1 / Phase 2 | 16 | EMD SeronoINDUSTRY | 3 | Oct 19, 2016 | clinicaltrials |
| NCT00952016 | Methotrexate in Metastatic Colorectal Cancer With MSH2 Deficiency(MESH) | terminated | Phase 2 | 2 | Royal Marsden NHS Foundation TrustOTHER | 1 | Oct 14, 2016 | clinicaltrials |
| NCT01937715 | A Study Of PF-05212384 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI In Metastatic Colorectal Cancer | terminated | Phase 1 / Phase 2 | 18 | PfizerINDUSTRY | 3 | Aug 18, 2016 | clinicaltrials |
| NCT01322815 | A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI | terminated | Phase 2 | 11 | Georgetown UniversityOTHER | 1 | Aug 15, 2016 | clinicaltrials |
| NCT01320683 | Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer | terminated | Phase 2 | 1 | City of Hope Medical CenterOTHER | 1 | Jul 19, 2016 | clinicaltrials |
| NCT01888965 | Maintenance Dovitinib for Colorectal and Pancreas Cancer | terminated | Phase 2 | 9 | Georgetown UniversityOTHER | 1 | Jul 19, 2016 | clinicaltrials |
| NCT01111292 | Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jul 12, 2016 | clinicaltrials |
| NCT01339000 | Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy | terminated | Phase 2 | 1 | National Cancer Institute (NCI)NIH | 1 | Jun 22, 2016 | clinicaltrials |
| NCT00216086 | Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer | terminated | Phase 2 | 22 | Gabi Chiorean, MDOTHER | 1 | Jun 6, 2016 | clinicaltrials |
| NCT01843452 | Phase II Study of Concomitant Intensity-modulated Radiotherapy Combined to Capecitabine, Mitomycin and Panitumumab in Patients With Stage II-IIIB Squamous-cell Carcinoma of the Anal Canal | terminated | Phase 2 | 8 | Centre Hospitalier Universitaire VaudoisOTHER | 1 | May 19, 2016 | clinicaltrials |
| NCT01483638 | Axitinib as Maintenance Treatment in Patients With Metastatic CRC(TTD-11-01) | terminated | Phase 2 | 84 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | May 12, 2016 | clinicaltrials |
| NCT00973193 | Preoperative Panitumumab and Radiotherapy in Rectal Cancer(PrePaRad) | terminated | Phase 2 | 20 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Apr 20, 2016 | clinicaltrials |
| NCT01858662 | Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors | terminated | Phase 2 | 4 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Apr 15, 2016 | clinicaltrials |
| NCT00271011 | A Study of Mitomycin C, Irinotecan, and Cetuximab | terminated | Phase 2 | 13 | University of Michigan Rogel Cancer CenterOTHER | 1 | Dec 3, 2015 | clinicaltrials |
| NCT01186705 | Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer | terminated | Phase 2 | 1 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 18, 2015 | clinicaltrials |
| NCT00019747 | Surgery With or Without Thalidomide in Treating Patients With Recurrent or Metastatic Colorectal Cancer | terminated | Phase 2 | 39 | National Institutes of Health Clinical Center (CC)NIH | 1 | Oct 28, 2015 | clinicaltrials |
| NCT01856322 | Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer | terminated | Phase 2 | 3 | National Cancer Institute (NCI)NIH | 1 | Oct 23, 2015 | clinicaltrials |
| NCT01004159 | Cetuximab Plus Irinotecan in Colorectal Cancer Patients Who Progressed After Failure With Cetuximab Plus Irinotecan | terminated | Phase 2 | 20 | Roswell Park Cancer InstituteOTHER | 1 | Oct 19, 2015 | clinicaltrials |
| NCT00717990 | Irinotecan, Capecitabine and Avastin for Metastatic Colorectal Cancer as Salvage Treatment | terminated | Phase 2 | 15 | University Hospital of CreteOTHER | 1 | Oct 7, 2015 | clinicaltrials |
| NCT00755118 | Lohp, 5-Fu/Lv and Bevacizumab, Alternative With Cpt-11, 5-Fu/Lv and Cetuximab In Metastatic Crc | terminated | Phase 2 | 24 | University Hospital of CreteOTHER | 1 | Oct 7, 2015 | clinicaltrials |
| NCT00250835 | Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer | terminated | Phase 2 | 38 | New Mexico Cancer Research AllianceOTHER | 1 | Sep 1, 2015 | clinicaltrials |
| NCT01300858 | A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients | terminated | Phase 1 / Phase 2 | 4 | EGEN, Inc.INDUSTRY | 1 | Jul 13, 2015 | clinicaltrials |
| NCT01375816 | Liposome-encapsulated Irinotecan Hydrochloride PEP02 or Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil as Second-Line Therapy in Treating Patients With Metastatic Colorectal Cancer(PEPCOL) | terminated | Phase 2 | 55 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jun 4, 2015 | clinicaltrials |
| NCT00459901 | Study of the Antitumor Activity of Capecitabine in Combination With Erlotinib in Patients With Metastatic Colorectal Cancer | terminated | Phase 2 | 13 | Peter KozuchOTHER | 1 | Apr 29, 2015 | clinicaltrials |
| NCT00390364 | Everolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous Therapy | terminated | Phase 2 | 1 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 8, 2014 | clinicaltrials |
| NCT01149434 | Study of JI-101 in Patients With Advanced Low Grade Endocrine Tumors, Ovarian Cancers or K-RAS Mutant Colon Cancers | terminated | Phase 1 / Phase 2 | 19 | University of UtahOTHER | 1 | Oct 6, 2014 | clinicaltrials |
| NCT00642746 | Erlotinib and Chemotherapy for 2nd Line Treatment (Tx) of Metastatic Colorectal Cancer (mCRC) | terminated | Phase 2 | 16 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 26, 2014 | clinicaltrials |
| NCT02228785 | A Study of the Safety and Tolerance of Three Doses of G17DT in Metastatic Colorectal Cancer(CC1C) | terminated | Phase 2 | 5 | Cancer Advances Inc.INDUSTRY | 0 | Aug 29, 2014 | clinicaltrials |
| NCT00538291 | Cetuximab and Capecitabine in Treating Patients With Metastatic Colorectal Cancer That Failed Irinotecan Treatment | terminated | Phase 2 | 13 | City of Hope Medical CenterOTHER | 1 | Aug 28, 2014 | clinicaltrials |
| NCT01365910 | Linifanib in Treating Patients With Advanced, Refractory Colorectal Cancer | terminated | Phase 2 | 30 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Aug 26, 2014 | clinicaltrials |
| NCT02204332 | Phase II-b Randomized Clinical Trial of Cabazitaxel in Metastatic Colorectal Cancer Resistant to Standard Treatment(COMETA) | terminated | Phase 2 | 38 | Hospital Clinico Universitario de SantiagoOTHER | 1 | Jul 30, 2014 | clinicaltrials |
Data updated 22 days agoSource updated Feb 5, 2018source: clinicaltrials