Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06126406 | Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors | recruiting | Phase 1 | 60 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Nov 13, 2023 | clinicaltrials |
| NCT06010862 | Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors | recruiting | Phase 1 | 36 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Nov 8, 2023 |
| clinicaltrials |
| NCT06118762 | Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal Cancer | recruiting | Phase 4 | 30 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT06116019 | Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)(ART-02) | recruiting | — | 649 | Charite University, Berlin, GermanyOTHER | 1 | Nov 3, 2023 | clinicaltrials |
| NCT05985109 | KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer | recruiting | Phase 2 | 98 | Peking University Cancer Hospital & InstituteOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT05450029 | Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer(SILAR) | recruiting | Phase 2 | 51 | Yanhong DengOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT05438836 | Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer(ROAR-A) | recruiting | — | 205 | Herlev HospitalOTHER | 1 | Sep 25, 2023 | clinicaltrials |
| NCT04616495 | Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases(TRASMETIR) | recruiting | — | 30 | Hospital Universitario La FeOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT06043466 | A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors | recruiting | Phase 1 | 30 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Sep 21, 2023 | clinicaltrials |
| NCT06043999 | Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | recruiting | N/A | 392 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT05962502 | Cetuximab Plus Irinotecan in Patients With NeoRAS Wild-type Metastatic Colorectal Cancer In Third-line Therapy | recruiting | Phase 2 | 54 | Sun Yat-sen UniversityOTHER | 1 | Aug 31, 2023 | clinicaltrials |
| NCT05336539 | A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou | recruiting | — | 80,000 | Singlera Genomics Inc.INDUSTRY | 1 | Aug 29, 2023 | clinicaltrials |
| NCT05879783 | Optical Biopsy for Peritoneal Nodules in Colorectal Patients | recruiting | N/A | 278 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT05984485 | The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer(TaLaR-02) | recruiting | Phase 3 | 766 | Sun Yat-sen UniversityOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05734300 | The "SPARCOL" Study | recruiting | N/A | 48 | Zealand University HospitalOTHER | 1 | Jul 25, 2023 | clinicaltrials |
| NCT05939661 | A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer(AMBITION) | recruiting | Phase 2 | 45 | Osaka UniversityOTHER | 1 | Jul 11, 2023 | clinicaltrials |
| NCT05797467 | Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients | recruiting | Phase 3 | 366 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | May 24, 2023 | clinicaltrials |
| NCT04959604 | Lymph Node Mapping Via Flourescent Dye in Colon Cancer | recruiting | N/A | 30 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | May 23, 2023 | clinicaltrials |
| NCT05853094 | Postoperative Effects of Different Enterostomy Approaches | recruiting | N/A | 300 | Fudan UniversityOTHER | 1 | May 19, 2023 | clinicaltrials |
| NCT05861505 | COLLISION RELAPSE Trial | recruiting | Phase 3 | 360 | Amsterdam UMC, location VUmcOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05316103 | Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy | recruiting | N/A | 68 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | May 12, 2023 | clinicaltrials |
| NCT04087421 | Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome | recruiting | Phase 3 | 114 | University of AarhusOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT05815082 | ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer | recruiting | Phase 3 | 490 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05797077 | Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA | recruiting | Phase 3 | 346 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 4, 2023 | clinicaltrials |
| NCT05772923 | Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision(OPAXX) | recruiting | N/A | 168 | The Netherlands Cancer InstituteOTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT05733000 | CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors | recruiting | Phase 2 | 94 | Northwestern UniversityOTHER | 1 | Mar 10, 2023 | clinicaltrials |
| NCT04245683 | Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population | recruiting | — | 50 | Bassett HealthcareOTHER | 1 | Mar 7, 2023 | clinicaltrials |
| NCT04842006 | Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer(SYNCOPE) | recruiting | N/A | 93 | Helsinki University Central HospitalOTHER | 1 | Mar 6, 2023 | clinicaltrials |
| NCT05136326 | Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer(CATARTIC) | recruiting | Phase 2 | 21 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Mar 1, 2023 | clinicaltrials |
| NCT04743102 | Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer(BIOPSY) | recruiting | N/A | 260 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05202314 | Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer(NACSOC-02) | recruiting | N/A | 20 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT05725200 | Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer(EVIDENT) | recruiting | Phase 2 | 40 | Oslo University HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT03466424 | Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer | recruiting | — | 9 | Fujian Medical University Union HospitalOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT04014530 | Pembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study(ATAPEMBRO) | recruiting | Phase 1 / Phase 2 | 47 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT05704413 | Digestive Biobank for Exploring Microbiota-host Interactions(BiomHost) | recruiting | — | 500 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 30, 2023 | clinicaltrials |
| NCT05696002 | Advanced Pelvic Surgical Oncology Database - Prospective Observational Study | recruiting | — | 300 | Glasgow Royal InfirmaryOTHER | 1 | Jan 25, 2023 | clinicaltrials |
| NCT04486131 | Lateral Nodal Recurrence in Rectal Cancer(LaNoReC) | recruiting | — | 200 | Amsterdam UMC, location VUmcOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT05676190 | Clinical Study on the Efficacy of Autologous Cell Factor Induced Killer Cells in the Treatment of Colorectal Cancer | recruiting | N/A | 80 | ShiCang YuOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT05236972 | PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer | recruiting | Phase 3 | 323 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2022 | clinicaltrials |
| NCT04871399 | Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer(CoME-In) | recruiting | N/A | 416 | University of Turin, ItalyOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT05495776 | Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer(MSIRus22) | recruiting | — | 2,500 | State Scientific Centre of Coloproctology, Russian FederationOTHER_GOV | 1 | Oct 25, 2022 | clinicaltrials |
| NCT05579353 | The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer | recruiting | — | 200 | Jingbo ChenOTHER | 1 | Oct 13, 2022 | clinicaltrials |
| NCT04527861 | Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer(CSILS) | recruiting | N/A | 710 | Ruijin HospitalOTHER | 1 | Oct 10, 2022 | clinicaltrials |
| NCT05566249 | A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Constructed Multi-center Registry | recruiting | — | 1,000 | Samsung Medical CenterOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT05563922 | Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma(OP-TNT) | recruiting | Phase 2 | 56 | Shanghai Zhongshan HospitalOTHER | 1 | Oct 3, 2022 | clinicaltrials |
| NCT04673955 | BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment(BERING-CRC) | recruiting | — | 500 | Pierre Fabre Pharma GmbHINDUSTRY | 2 | Sep 29, 2022 | clinicaltrials |
| NCT05528783 | Application of FIT-DNA Detection in Following Colorectal Cancer Resection-Implications for Surveillance | recruiting | — | 200 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT05529615 | Circulating Tumor DNA Guided Adjuvant Chemotherapy for Colon Cancer(CTAC) | recruiting | N/A | 2,684 | Peking University Cancer Hospital & InstituteOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT04389086 | Induction Chemotherapy for Locally Recurrent Rectal Cancer(PelvEx II) | recruiting | Phase 3 | 364 | Catharina Ziekenhuis EindhovenOTHER | 5 | Sep 6, 2022 | clinicaltrials |
| NCT05434026 | Chinese Colorectal Cancer Database(CCCD) | recruiting | — | 200,000 | Beijing Friendship HospitalOTHER | 1 | Aug 3, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Nov 13, 2023source: clinicaltrials