Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04450758 | Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma(ACBC) | recruiting | — | 1,000 | Skane University HospitalOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT05523245 | Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI(DLARC) | recruiting | — | 1,700 | Sixth Affiliated Hospital, Sun Yat-sen University |
| 1 |
| Apr 23, 2026 |
| clinicaltrials |
| NCT06475352 | Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme(FUDOSE) | recruiting | Phase 2 | 400 | UNICANCEROTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06720987 | A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies | recruiting | Phase 1 | 140 | Kumquat Biosciences Inc.INDUSTRY | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06957015 | A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size(EndoAIM) | recruiting | N/A | 278 | Chinese University of Hong KongOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT07381322 | A Study on the Accurate Evaluation of Pseudoprogression of Rectal Cancer Immunotherapy Based on Multitemporal and Multiparameter MRI | recruiting | — | 300 | Peiyi XieOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06965166 | Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer | recruiting | — | 200 | Mayo ClinicOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07020221 | A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors | recruiting | Phase 1 / Phase 2 | 295 | Verastem, Inc.INDUSTRY | 2 | Apr 22, 2026 | clinicaltrials |
| NCT07198581 | AI-Assisted Chemotherapy Side Effect Management(ALLIANCE) | recruiting | N/A | 174 | Incheon St.Mary's HospitalOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07412613 | Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer | recruiting | Phase 3 | 386 | AkesoINDUSTRY | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07546565 | Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis(UMC-Colprep) | recruiting | N/A | 74 | University Medical Center Ho Chi Minh City (UMC)OTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT06424522 | A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients | recruiting | N/A | 80 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07393048 | Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant Therapy for Rectal Cancer(ctDNA-MRD-RC) | recruiting | — | 60 | Beijing Friendship HospitalOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07407647 | Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer | recruiting | Phase 2 | 25 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT05969860 | At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer | recruiting | Phase 2 | 220 | Mayo ClinicOTHER | 1 | Apr 20, 2026 | clinicaltrials |
| NCT06280495 | Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients | recruiting | Phase 2 / Phase 3 | 156 | Sun Yat-sen UniversityOTHER | 1 | Apr 20, 2026 | clinicaltrials |
| NCT07405476 | Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment | recruiting | Phase 2 | 38 | Emory UniversityOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07536113 | Assessing the Efficacy and Safety of ctDNA-driven Selection for Anti-EGFR Retreatment in a Real World Metastatic Colorectal Cancer Patients Cohort (the REalCHALLENGE Study)(RealCHALLENGE) | recruiting | — | 250 | Niguarda HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07537998 | Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial. | recruiting | Phase 2 / Phase 3 | 160 | Pei-Rong DingOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT06569368 | Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy | recruiting | Phase 2 | 60 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT06898996 | FITting Non-invasive Tests in Lynch Syndrome Surveillance | recruiting | — | 400 | University of ChicagoOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT07534852 | NIMA-Colon Cancer Study(NIMA) | recruiting | N/A | 120 | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT07535021 | The Effect of Mandala Art Therapy, Psychological Resilience, Coping With Cancer, Colorectal Cancer Surgery | recruiting | N/A | 70 | Cumhuriyet UniversityOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT04693377 | Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial | recruiting | N/A | 40 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT06274190 | Personalized Care Pathways for Bowel Symptoms in Rectal Cancer patients_development of E-diary(Treatable) | recruiting | N/A | 158 | KU LeuvenOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT06669572 | Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment | recruiting | Phase 2 | 35 | University of ChicagoOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT07353645 | KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer | recruiting | Phase 1 / Phase 2 | 49 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT07090291 | China Colorectal Cancer Screening Trial 1 (C-Cost1) | recruiting | N/A | 60,300 | Zhejiang UniversityOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT07527026 | A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer | recruiting | Phase 2 | 44 | Chinese PLA General HospitalOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT07529301 | Functional and Respiratory Predictors of Early Postoperative Outcomes | recruiting | — | 42 | Müşerref Ebru YALÇINOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT06362369 | A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy | recruiting | Phase 1 / Phase 2 | 126 | 7 Hills Pharma, LLCINDUSTRY | 1 | Apr 13, 2026 | clinicaltrials |
| NCT06837831 | Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin | recruiting | N/A | 274 | Qianfoshan HospitalOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT07501845 | Registry Maastro Applicator | recruiting | — | 999 | Maastricht Radiation OncologyOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT07523919 | Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes | recruiting | — | 52 | Inonu UniversityOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT04624555 | The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors | recruiting | — | 50 | Case Comprehensive Cancer CenterOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT06746012 | Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers | recruiting | N/A | 70 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT06955767 | Measurement of MMP-14 Protein, a Potential New Marker for Colorectal Cancer Detection, in Plasma Vesicles Named Exosomes(EXOSCOL02) | recruiting | N/A | 650 | CHU de ReimsOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT07042685 | Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer | recruiting | Phase 2 | 50 | The Methodist Hospital Research InstituteOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT06162650 | Total Neoadjuvant Therapy in Rectal Cancer | recruiting | Phase 2 | 42 | National Cheng-Kung University HospitalOTHER | 1 | Apr 8, 2026 | clinicaltrials |
| NCT04812912 | Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer | recruiting | — | 120 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07506109 | A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer | recruiting | Phase 2 | 49 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07514754 | Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients(GALENOS 2) | recruiting | N/A | 52 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT04622423 | Advanced Therapies for Liver Metastases(LiMeT) | recruiting | — | 625 | IRCCS San RaffaeleOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT07511413 | GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients(GALENOS 1) | recruiting | — | 110 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT06281405 | CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer(TORCH-iTNT) | recruiting | Phase 2 | 192 | Fudan UniversityOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT06848465 | LDRT Combined With Immunochemotherapy for Colorectal Cancer With Liver Metastasis | recruiting | Phase 1 | 9 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT07510321 | FL-261 Imaging for Cancer Diagnosis and Staging | recruiting | — | 12 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT05447923 | Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities | recruiting | N/A | 450 | Mayo ClinicOTHER | 1 | Apr 2, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 23, 2026source: clinicaltrials