Subtype
Malignant Intestinal Neoplasm
CI-CAN-00001137Explore in graph →
1,666 active trials21 approved drugs383 evidence items
- NCIt
- C4572
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Subtype
CI-CAN-00001137Explore in graph →
Clinical trials
7,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (772)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00511862 | TheraSphere for the Treatment of Liver Metastases | completed | Phase 2 | 151 | Boston Scientific CorporationINDUSTRY | 1 | May 13, 2021 | clinicaltrials |
| NCT02340949 | Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer(RIA) | completed | Phase 2 | 180 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 0 | May 3, 2021 |
| clinicaltrials |
| NCT01345526 | Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream | completed | Phase 2 | 124 | Universitätsmedizin MannheimOTHER | 2 | Apr 30, 2021 | clinicaltrials |
| NCT02217020 | Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer(FORTUNE) | completed | Phase 2 | 100 | Sun Yat-sen UniversityOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT01075048 | ARQ 197 in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 131 | Daiichi SankyoINDUSTRY | 5 | Apr 8, 2021 | clinicaltrials |
| NCT02811497 | Study of Azacitidine and Durvalumab in Advanced Solid Tumors(METADUR) | completed | Phase 2 | 28 | University Health Network, TorontoOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT02046174 | Open-Label Phase IIb Efficacy Trial of Cancer Macrobeads Compared to Best Supportive Care in Colorectal Cancer Patients | completed | Phase 2 | 70 | The Rogosin InstituteOTHER | 1 | Mar 24, 2021 | clinicaltrials |
| NCT04795180 | Pilot Randomized Evaluation of Butyrate Irrigation Before Ileostomy Closure on the Colonic Mucosa in Rectal Cancer Patients (BUTYCLO)(BUTYCLO) | completed | Phase 2 | 45 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT01037790 | Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer | completed | Phase 2 | 304 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 11, 2021 | clinicaltrials |
| NCT00066274 | Comparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | — | UNICANCEROTHER | 1 | Mar 2, 2021 | clinicaltrials |
| NCT02953782 | Study of Magrolimab (Hu5F9-G4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer | completed | Phase 1 / Phase 2 | 78 | Gilead SciencesINDUSTRY | 1 | Mar 1, 2021 | clinicaltrials |
| NCT00104689 | Capecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 60 | UNICANCEROTHER | 1 | Feb 21, 2021 | clinicaltrials |
| NCT01327612 | Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) | completed | Phase 2 | 12 | AmgenINDUSTRY | 3 | Feb 21, 2021 | clinicaltrials |
| NCT01927341 | Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors | completed | Phase 1 / Phase 2 | 53 | PfizerINDUSTRY | 7 | Feb 18, 2021 | clinicaltrials |
| NCT02641691 | Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum(NORMAL-R) | completed | Phase 2 | 20 | Washington University School of MedicineOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT00006050 | Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | completed | Phase 2 | — | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00423696 | Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | completed | Phase 2 | 145 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02981524 | Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer | completed | Phase 2 | 17 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT01481545 | Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer(BRANCH) | completed | Phase 2 | 62 | National Cancer Institute, NaplesOTHER | 0 | Feb 3, 2021 | clinicaltrials |
| NCT03031444 | Perioperative Chemotherapy Plus Cetuximab Versus Chemotherapy Alone for High Risk Resectable Colorectal Liver Metastasis(PARECEC) | completed | Phase 2 / Phase 3 | 135 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT03443661 | Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer | completed | Phase 2 | 50 | Aiping ZhouUNKNOWN | 1 | Feb 1, 2021 | clinicaltrials |
| NCT00637091 | Efficacy Analysis of Cetuximab Plus Irinotecan in Patients With Wild-type KRAS Without Regard to Epidermal Growth Factor Receptor (EGFR) Expressions | completed | Phase 2 | 40 | Asan Medical CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT02164916 | S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer | completed | Phase 2 | 106 | SWOG Cancer Research NetworkNETWORK | 1 | Dec 30, 2020 | clinicaltrials |
| NCT01703390 | Biomarker Directed Treatment in Metastatic Colorectal Cancer | completed | Phase 2 | 47 | Arbeitsgemeinschaft medikamentoese TumortherapieOTHER | 1 | Dec 21, 2020 | clinicaltrials |
| NCT00748215 | Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan | completed | Phase 2 | 100 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 2, 2020 | clinicaltrials |
| NCT00628810 | Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 86 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 9, 2020 | clinicaltrials |
| NCT01258998 | Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma | completed | Phase 2 | 60 | National Cancer Institute (NCI)NIH | 1 | Nov 4, 2020 | clinicaltrials |
| NCT01417494 | 1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 102 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 3, 2020 | clinicaltrials |
| NCT01867697 | Nordic 8 - A Phase II Trial | completed | Phase 2 | 173 | Per PfeifferOTHER | 3 | Oct 30, 2020 | clinicaltrials |
| NCT00006366 | Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum | completed | Phase 2 | — | Radiation Therapy Oncology GroupNETWORK | 2 | Oct 22, 2020 | clinicaltrials |
| NCT01858649 | Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Bevacizumab With FOLFOX or FOLFIRI.(BEV-ONCO2012) | completed | Phase 2 | 60 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT02469480 | Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study. | completed | Phase 2 | 64 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Oct 19, 2020 | clinicaltrials |
| NCT01896856 | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 118 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 2 | Oct 6, 2020 | clinicaltrials |
| NCT03152565 | Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients(AVEVAC) | completed | Phase 1 / Phase 2 | 28 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Oct 6, 2020 | clinicaltrials |
| NCT00033371 | Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis | completed | Phase 2 | 205 | National Cancer Institute (NCI)NIH | 1 | Sep 29, 2020 | clinicaltrials |
| NCT01397305 | An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer | completed | Phase 1 / Phase 2 | 24 | Isofol Medical ABINDUSTRY | 1 | Sep 9, 2020 | clinicaltrials |
| NCT01208103 | Bevacizumab, Capecitabine, and Oxaliplatin in Treating Advanced Small Intestinal or Ampulla of Vater Adenocarcinoma | completed | Phase 2 | 30 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 3, 2020 | clinicaltrials |
| NCT01209325 | Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males | completed | Phase 2 | 149 | AIDS Malignancy ConsortiumNETWORK | 2 | Aug 11, 2020 | clinicaltrials |
| NCT00003225 | Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 23 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00002933 | Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer | completed | Phase 2 | 21 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 27, 2020 | clinicaltrials |
| NCT00437268 | A Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal Cancer | completed | Phase 2 | 26 | Eli Lilly and CompanyINDUSTRY | 1 | Jul 21, 2020 | clinicaltrials |
| NCT00612586 | Study of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon Cancer | completed | Phase 2 | 117 | Eli Lilly and CompanyINDUSTRY | 6 | Jul 21, 2020 | clinicaltrials |
| NCT03168139 | Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer(Keynote-559) | completed | Phase 1 / Phase 2 | 20 | TME Pharma AGINDUSTRY | 1 | Jul 8, 2020 | clinicaltrials |
| NCT00867334 | New Individualized Therapy Trial for Metastatic Colorectal Cancer(NITMEC) | completed | Phase 1 / Phase 2 | 10 | Inova Health Care ServicesOTHER | 1 | Jun 30, 2020 | clinicaltrials |
| NCT01832467 | Cetuximab Rechallenge Study | completed | Phase 2 | 17 | Chinese University of Hong KongOTHER | 1 | Jun 18, 2020 | clinicaltrials |
| NCT02497157 | Bevacizumab + Triplet Treatment for Untreated With Chemotherapy Metastatic Colorectal Cancer(BeTRI) | completed | Phase 2 | 45 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Jun 17, 2020 | clinicaltrials |
| NCT02196688 | Study of Fruquintinib in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 71 | Hutchison Medipharma LimitedINDUSTRY | 1 | Jun 16, 2020 | clinicaltrials |
| NCT01363843 | Complete Neoadjuvant Treatment for REctal Cancer (CONTRE) | completed | Phase 2 | 39 | William Sikov MDOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT00021398 | Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer | completed | Phase 2 | 23 | Fox Chase Cancer CenterOTHER | 1 | Jun 5, 2020 | clinicaltrials |
| NCT00967616 | Study of CS-7017 in Combination With FOLFIRI in Subjects With Metastatic Colorectal Cancer Who Failed First-Line Therapy | completed | Phase 2 | 100 | Daiichi SankyoINDUSTRY | 5 | May 4, 2020 | clinicaltrials |
Data updated 23 days agoSource updated May 13, 2021source: clinicaltrials