Subtype
Malignant Intestinal Neoplasm
CI-CAN-00001137Explore in graph →
1,666 active trials21 approved drugs383 evidence items
- NCIt
- C4572
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Subtype
CI-CAN-00001137Explore in graph →
Clinical trials
7,771 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (772)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06646809 | Reducing Inflammatory Syndrome in Surgery - Colorectal (RISIS-CR) Trial(RISIS-CR) | unknown | Phase 3 | 80 | National University Hospital, SingaporeOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT06275958 | DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer(DOSAGE) | recruiting | Phase 3 | 587 | Leiden University Medical CenterOTHER | 1 | Oct 16, 2024 |
| clinicaltrials |
| NCT02563002 | Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177) | completed | Phase 3 | 307 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Oct 3, 2024 | clinicaltrials |
| NCT06616259 | First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Controlled, Phase III Study(CAPCET-III) | not yet recruiting | Phase 3 | 452 | Meng QiuOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT04737187 | Phase III Study of Trifluridine/Tipiracil With and Without Bevacizumab in Refractory Metastatic Colorectal Cancer Patients(SUNLIGHT) | completed | Phase 3 | 492 | Taiho Oncology, Inc.INDUSTRY | 14 | Sep 24, 2024 | clinicaltrials |
| NCT06609551 | ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study(ZJCH-CRCC-1) | recruiting | Phase 3 | 312 | Zhejiang Cancer HospitalOTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT04488159 | Immunoscore As Decision Guidance for Adjuvant Chemotherapy in Colon Cancer(iMAGINE) | withdrawn | Phase 3 | 0 | Johannes Laengle, MD, PhDOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT01607957 | Study of TAS-102 in Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies(RECOURSE) | completed | Phase 3 | 800 | Taiho Oncology, Inc.INDUSTRY | 13 | Sep 19, 2024 | clinicaltrials |
| NCT05168839 | Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage(FLUOCOL-1) | recruiting | Phase 3 | 1,010 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06185556 | COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases(COLDFIRE-III) | recruiting | Phase 2 / Phase 3 | 78 | Amsterdam UMC, location VUmcOTHER | 1 | Aug 23, 2024 | clinicaltrials |
| NCT06566755 | Cadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer | recruiting | Phase 3 | 30 | Caigang LiuOTHER | 1 | Aug 22, 2024 | clinicaltrials |
| NCT00297791 | COLOR II: Laparoscopic Versus Open Rectal Cancer Removal(COLORII) | completed | Phase 3 | 1,044 | Nova Scotia Health AuthorityOTHER | 9 | Aug 21, 2024 | clinicaltrials |
| NCT05223673 | Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer(COLSTAR) | terminated | Phase 3 | 7 | Institut de Recherches Internationales ServierOTHER | 6 | Aug 20, 2024 | clinicaltrials |
| NCT03520946 | RAMucirumab in Combination Wth TAS102 vs. TAS102 Alone in Chemotherapy Refractory Metastatic Colorectal Cancer Patients(RAMTAS) | completed | Phase 3 | 430 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT05939687 | Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection(ProMeLAR) | recruiting | Phase 3 | 142 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT02135419 | Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions(ANCHOR) | completed | Phase 3 | 4,446 | AIDS Malignancy ConsortiumNETWORK | 2 | Jul 26, 2024 | clinicaltrials |
| NCT03306394 | A Study of Trifluridine/Tipiracil (Also Known as S 95005 or TAS-102) in Patients With a Pretreated Colorectal Cancer That Has Spread (Metastatic).(PRECONNECT) | completed | Phase 3 | 907 | Institut de Recherches Internationales ServierOTHER | 16 | Jul 25, 2024 | clinicaltrials |
| NCT06509126 | Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer(IMPROVE-2) | recruiting | Phase 3 | 500 | National Cancer Institute, NaplesOTHER | 1 | Jul 19, 2024 | clinicaltrials |
| NCT06243393 | Sacituzumab Govitecan in Metastatic Colorectal Cancer(TROPHIT1) | recruiting | Phase 2 / Phase 3 | 80 | University Hospital HeidelbergOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT02355379 | Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over(ADAGE) | unknown | Phase 3 | 774 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Jul 8, 2024 | clinicaltrials |
| NCT06450574 | Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study)(TAUTEM-T1) | not yet recruiting | Phase 3 | 106 | Corporacion Parc TauliOTHER | 0 | Jun 10, 2024 | clinicaltrials |
| NCT06443671 | Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer(PKUCH-R09) | not yet recruiting | Phase 2 / Phase 3 | 132 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 5, 2024 | clinicaltrials |
| NCT05954078 | Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer | recruiting | Phase 3 | 340 | Fudan UniversityOTHER | 1 | May 20, 2024 | clinicaltrials |
| NCT01345175 | Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer | completed | Phase 3 | 69 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT06139926 | Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients With Colorectal Tumors | unknown | Phase 3 | 126 | First Affiliated Hospital of Chongqing Medical UniversityOTHER | 1 | Apr 9, 2024 | clinicaltrials |
| NCT06343116 | Nimotuzumab Combined With Trifluridine/Tipiracil in the Treatment of Refractory Metastatic Colorectal Cancer(NOTABLE-308) | not yet recruiting | Phase 3 | 420 | Biotech Pharmaceutical Co., Ltd.OTHER | 0 | Apr 2, 2024 | clinicaltrials |
| NCT03781154 | Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors | completed | Phase 3 | 31 | University of Colorado, DenverOTHER | 1 | Mar 20, 2024 | clinicaltrials |
| NCT03464305 | ASPIRIN Trial Belgium(ASPIRIN) | active not recruiting | Phase 3 | 148 | University Hospital, AntwerpOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT02301286 | A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients(ASPIRIN) | active not recruiting | Phase 3 | 770 | Leiden UniversityOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT02102789 | A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis | unknown | Phase 3 | 142 | Yuhong LiOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT05726097 | Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure | completed | Phase 3 | 147 | Region SkaneOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT03413254 | Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases(COLOPEC-II) | active not recruiting | Phase 3 | 389 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Feb 23, 2024 | clinicaltrials |
| NCT00565708 | Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers(ASCOLT) | unknown | Phase 3 | 1,587 | National Cancer Centre, SingaporeOTHER | 10 | Feb 2, 2024 | clinicaltrials |
| NCT01515787 | PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery | unknown | Phase 2 / Phase 3 | 1,194 | Alliance for Clinical Trials in OncologyOTHER | 4 | Feb 2, 2024 | clinicaltrials |
| NCT05921942 | The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer | completed | Phase 3 | 70 | Ain Shams UniversityOTHER | 1 | Feb 2, 2024 | clinicaltrials |
| NCT06229041 | Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) | recruiting | Phase 3 | 472 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 29, 2024 | clinicaltrials |
| NCT03500874 | Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLM | terminated | Phase 3 | 92 | Sun Yat-sen UniversityOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT04338191 | mFOLFOXIRI Versus mFOLFOX6 as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer(FANTASTIC) | unknown | Phase 3 | 638 | Sun Yat-sen UniversityOTHER | 1 | Dec 27, 2023 | clinicaltrials |
| NCT05631041 | Effect of Silymarin in Metastatic Colorectal Cancer Patients | unknown | Phase 3 | 64 | Tanta UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT02519140 | Assessing How the Viscosity of Submucosal Gel Injections Helps With Endoscopic Mucosal Resections | withdrawn | Phase 3 | 0 | Antonios LikourezosOTHER | 1 | Dec 4, 2023 | clinicaltrials |
| NCT03414983 | An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread(CheckMate 9X8) | completed | Phase 2 / Phase 3 | 196 | Bristol-Myers SquibbINDUSTRY | 5 | Nov 18, 2023 | clinicaltrials |
| NCT06134388 | Sulfasalazine in Patients With Metastatic Colorectal Cancer | recruiting | Phase 3 | 50 | Tanta UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT02753127 | A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer(CanStem303C) | completed | Phase 3 | 1,253 | Sumitomo Pharma America, Inc.INDUSTRY | 16 | Nov 15, 2023 | clinicaltrials |
| NCT02394795 | Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC(PARADIGM) | completed | Phase 3 | 823 | TakedaINDUSTRY | 1 | Nov 1, 2023 | clinicaltrials |
| NCT06097416 | Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer | not yet recruiting | Phase 3 | 100 | St. James's Hospital, IrelandOTHER | 0 | Oct 25, 2023 | clinicaltrials |
| NCT02551237 | Neoadjuvant Treatment for Advanced Rectal Carcinoma(NACRE) | completed | Phase 3 | 103 | UNICANCEROTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT00958737 | Combination Chemotherapy for 3 Months or 6 Months in Treating Patients With Stage III Colon Cancer(IDEA) | unknown | Phase 3 | 2,000 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Sep 29, 2023 | clinicaltrials |
| NCT02614534 | Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal Carcinoma(HIPECT4) | unknown | Phase 3 | 200 | Maimónides Biomedical Research Institute of CórdobaOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT06049901 | Nitazoxanide in Patients With Metastatic Colorectal Cancer | unknown | Phase 3 | 60 | Tanta UniversityOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT01606098 | The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer(CAIRO4) | completed | Phase 3 | 206 | Dutch Colorectal Cancer GroupOTHER | 2 | Sep 13, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Oct 17, 2024source: clinicaltrials