Subtype
Malignant Intestinal Neoplasm
CI-CAN-00001137Explore in graph →
1,666 active trials21 approved drugs383 evidence items
- NCIt
- C4572
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00001137Explore in graph →
Clinical trials
7,771 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (772)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04845490 | Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy(WUHIPEC02) | unknown | Phase 2 | 201 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 0 | Feb 21, 2022 | clinicaltrials |
| NCT03221400 | PEN-866 in Patients With Advanced Solid Malignancies | unknown | Phase 1 / Phase 2 | 340 | Tarveda TherapeuticsINDUSTRY |
| 1 |
| Feb 17, 2022 |
| clinicaltrials |
| NCT05241574 | Planned Non-operative Management for Rectal Cancer | unknown | Phase 2 | 23 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Feb 15, 2022 | clinicaltrials |
| NCT05200299 | mFOLFOXIRI Compared to mFOLFOX6 or CapeOx as Adjuvant Chemotherapy for Stage IIIB or IIIC Colorectal Cancer | unknown | Phase 2 | 100 | First Affiliated Hospital of Wenzhou Medical UniversityOTHER | 1 | Jan 20, 2022 | clinicaltrials |
| NCT05130021 | A Clincal Study of Max-40279-01 in Patients With Advanced Colorectal Cancer | unknown | Phase 2 | 130 | Maxinovel Pty., Ltd.INDUSTRY | 1 | Dec 6, 2021 | clinicaltrials |
| NCT04764006 | Surufatinib Combined With Sintilimab for Advanced MSS-Type Colorectal Cancer : a Phase II Study | unknown | Phase 2 | 10 | Fujian Cancer HospitalOTHER_GOV | 1 | Nov 4, 2021 | clinicaltrials |
| NCT04582981 | Fruquintinib and Raltitrexed Versus Fruquintinib Monotherapy in Advanced Colorectal Cancer | unknown | Phase 2 | 136 | Fudan UniversityOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT05077839 | Trifluridine/Tipiracil Combined With Oxaliplatin and Bevacizumab Versus XELOX Plus Bevacizumab in mCRC(TOBACO) | unknown | Phase 2 | 184 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Oct 25, 2021 | clinicaltrials |
| NCT05068206 | A Clinical Study to Compare the Efficacy and Safety of AK105 Plus Anlotinib and Capecitabine/Oxaliplatin (CapeOx) , Anlotinib Plus CapeOx, Bevacizumab Plus CapeOx | unknown | Phase 2 | 120 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Oct 20, 2021 | clinicaltrials |
| NCT02826837 | LEAC-102 for Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 30 | Taiwan Leader Biotech Corp.INDUSTRY | 0 | Oct 6, 2021 | clinicaltrials |
| NCT02948348 | Study to Nivolumab Following Preoperative Chemoradiotherapy | unknown | Phase 1 / Phase 2 | 90 | Takayuki YoshinoOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT05035914 | Anlotinib Combined With mXELIRI as Second-line Treatment of Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 94 | Guangzhou University of Traditional Chinese MedicineOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT03126071 | Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer | unknown | Phase 2 | 100 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04241731 | A Study of Cetuximab Plus Raltitrexed for Maintenance Treatment in Advanced Colorectal Cancer | unknown | Phase 2 | 50 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04324476 | A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer | unknown | Phase 2 | 50 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04948034 | The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE) | unknown | Phase 2 | 68 | Fudan UniversityOTHER | 1 | Aug 27, 2021 | clinicaltrials |
| NCT04466254 | Efficacy and Safety Study of Combination of CPGJ602 and Chemotherapy, in First Line, With Wild KRAS/NRAS/BRAF in Metastatic Colorectal Cancer | unknown | Phase 2 | 75 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Aug 23, 2021 | clinicaltrials |
| NCT03727763 | Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT) | unknown | Phase 2 | 30 | Shanghai Changzheng HospitalOTHER | 1 | Aug 19, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04988191 | Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Peking UniversityOTHER | 1 | Aug 3, 2021 | clinicaltrials |
| NCT04969029 | Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT04380012 | A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer | unknown | Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 15, 2021 | clinicaltrials |
| NCT04293419 | Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer(DUREC) | unknown | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT04929652 | Surufatinib Combine With Immunotherapy and Chemotherapy for Second-line Treatment in Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 48 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT04664504 | A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk | unknown | Phase 2 | 150 | Jing Jin, M.D.UNKNOWN | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04907864 | Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)(MIRACLE) | unknown | Phase 2 | 112 | Kil Yeon LeeOTHER | 1 | Jun 1, 2021 | clinicaltrials |
| NCT04535024 | The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer | unknown | Phase 2 | 60 | Fudan UniversityOTHER | 1 | May 11, 2021 | clinicaltrials |
| NCT02942706 | Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC | unknown | Phase 2 / Phase 3 | 200 | Ruijin HospitalOTHER | 0 | Apr 30, 2021 | clinicaltrials |
| NCT02167321 | Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision | unknown | Phase 2 | 90 | Yonsei UniversityOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT04838496 | Induction Chemotherapy for Locally Advanced Rectal Cancer(MEND-IT) | unknown | Phase 2 | 128 | Catharina Ziekenhuis EindhovenOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT04833036 | c-CetuIRI Versus Ersecond-line Irinotecan s-IRI-CetuIRI | unknown | Phase 2 | 120 | Fudan UniversityOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT04816045 | Neoadjuvant Electrochemotherapy for Colorectal Cancer - a Randomized Controlled Trial | unknown | Phase 1 / Phase 2 | 24 | Zealand University HospitalOTHER | 0 | Mar 25, 2021 | clinicaltrials |
| NCT04423965 | A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC | unknown | Phase 2 | 220 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer(CORT) | unknown | Phase 2 | 60 | Zhou FuxiangOTHER | 1 | Mar 17, 2021 | clinicaltrials |
| NCT03329664 | Autologous Killer Cell Therapy in Colon Cancer Patients | unknown | Phase 1 / Phase 2 | 20 | Sabz BiomedicalsINDUSTRY | 1 | Mar 15, 2021 | clinicaltrials |
| NCT04775862 | A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer. | unknown | Phase 2 | 60 | National Guard Health AffairsOTHER_GOV | 1 | Mar 1, 2021 | clinicaltrials |
| NCT04749381 | The Role of TCM on ERAS of Rectal Cancer Patients(RCT) | unknown | Phase 2 | 264 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 11, 2021 | clinicaltrials |
| NCT04737213 | SGM-101 in Colorectal Lung Metastases(SGM-CLM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT04508452 | A Phase II Prospective Trial of mXELOXIRI Reintroduction for mCRC | unknown | Phase 2 | 91 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04734249 | Second-line Surufatinib Combined With Chemotherapy in Advanced CRC | unknown | Phase 2 | 56 | Fujian Cancer HospitalOTHER_GOV | 0 | Feb 2, 2021 | clinicaltrials |
| NCT04695470 | Phase II Trial of Fruquintinib With Sintilimab in Treating Selected Refractory Metastatic Colorectal Cancer Patients | unknown | Phase 2 | 70 | Aiping ZhouUNKNOWN | 1 | Jan 7, 2021 | clinicaltrials |
| NCT04110093 | Regorafenib Plus PD-1 Inhibitor in Patients With Colorectal Cancer | unknown | Phase 1 / Phase 2 | 120 | Shanghai Changzheng HospitalOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT04668976 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | unknown | Phase 2 | 100 | Benaroya Research InstituteOTHER | 1 | Dec 21, 2020 | clinicaltrials |
| NCT04674696 | Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer(SHORT-ICAR) | unknown | Phase 2 | 54 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Dec 19, 2020 | clinicaltrials |
| NCT04663763 | Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 | 40 | Zhejiang Cancer HospitalOTHER | 1 | Dec 11, 2020 | clinicaltrials |
| NCT04231552 | Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer | unknown | Phase 1 / Phase 2 | 30 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Nov 30, 2020 | clinicaltrials |
| NCT04264676 | Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer | unknown | Phase 2 | 294 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT04642924 | SGM-101 in Locally Advanced and Recurrent Rectal Cancer(SGM-LARRC) | unknown | Phase 2 / Phase 3 | 203 | Leiden University Medical CenterOTHER | 1 | Nov 24, 2020 | clinicaltrials |
| NCT03909724 | Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC)(SUNRISE-CRC) | unknown | Phase 2 / Phase 3 | 60 | Amsterdam UMC, location VUmcOTHER | 1 | Nov 13, 2020 | clinicaltrials |
Data updated 22 days agoSource updated Feb 21, 2022source: clinicaltrials