Subtype
Malignant Hepatobiliary Neoplasm
CI-CAN-00001136Explore in graph →
1,160 active trials17 approved drugs42 evidence items
- NCIt
- C8609
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00001136Explore in graph →
Clinical trials
5,029 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (561)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03071458 | Mutational Landscape in Hepatocellular Carcinoma(MUTHEC) | completed | — | 808 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Dec 10, 2025 | clinicaltrials |
| NCT07272265 | The Effectiveness and Safety in High-risk Patients Receiving First-line Atezolizumab and Bevacizumab Combined With HAIC for HCC: a Retrospective Study | completed | N/A | 300 | Sun Yat-sen UniversityOTHER |
| 1 |
| Dec 9, 2025 |
| clinicaltrials |
| NCT03963206 | Cabozantinib toLERANCE Study in HepatoCellular Carcinoma (CLERANCE)(CLERANCE) | completed | Phase 4 | 110 | Hospices Civils de LyonOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT05384184 | Next Generation " Pre-clinical Model for Colorectal Cancer Metastases and Hepatocellular Carcinomas(BORG) | completed | — | 48 | Assistance Publique Hopitaux De MarseilleOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT04828486 | Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer | completed | Phase 2 | 14 | Mayo ClinicOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT06294808 | Predicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC | completed | — | 1,043 | National Cancer Centre, SingaporeOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT07153783 | Interventional AI-Human Collaboration for Liver Tumor Diagnosis | completed | N/A | 10,333 | Shengjing HospitalOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT05622071 | Testing Immunotherapy for Patients With Liver Cancer and Moderately Altered Liver Functions(HESTIA) | completed | Phase 2 | 50 | UNICANCEROTHER | 1 | Nov 17, 2025 | clinicaltrials |
| NCT04874519 | Registry to Collect Health Information Related to Fibrolamellar Cancer | completed | — | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 12, 2025 | clinicaltrials |
| NCT00183885 | A Phase II Study of Intra-arterial Chemotherapy With Cisplatin and Mitomycin-C in Patients With Hepatocellular Carcinoma | completed | Phase 2 | 76 | University of Southern CaliforniaOTHER | 1 | Oct 30, 2025 | clinicaltrials |
| NCT05328167 | Contrast-Enhanced Ultrasound for the Prediction of Bile Duct Cancer Response to Radioembolization Treatment | completed | Phase 2 | 16 | Thomas Jefferson UniversityOTHER | 1 | Oct 28, 2025 | clinicaltrials |
| NCT05091346 | A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors | completed | Phase 1 / Phase 2 | 89 | Eisai Inc.INDUSTRY | 4 | Oct 24, 2025 | clinicaltrials |
| NCT02159989 | Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery | completed | Phase 1 | 83 | National Cancer Institute (NCI)NIH | 1 | Oct 20, 2025 | clinicaltrials |
| NCT03412773 | A Study of Tislelizumab Versus Sorafenib in Participants With Unresectable Hepatocellular Carcinoma (HCC) | completed | Phase 3 | 684 | BeiGeneINDUSTRY | 11 | Oct 14, 2025 | clinicaltrials |
| NCT05293496 | A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors | completed | Phase 1 | 31 | MacroGenicsINDUSTRY | 1 | Oct 14, 2025 | clinicaltrials |
| NCT03819088 | Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer | completed | N/A | 17 | Emory UniversityOTHER | 1 | Oct 9, 2025 | clinicaltrials |
| NCT02799212 | Evaluation of Postoperative Ascites After Somatostatin Infusion Following Hepatectomy for Hepatocellular Carcinoma(SOMAPROTECT01) | completed | Phase 3 | 179 | Hospices Civils de LyonOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT07204262 | Trajectory-Based Prognostic Modeling in Hepatocellular Carcinoma | completed | — | 379 | Xu Yong, MDOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT03044587 | Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer(NIFE) | completed | Phase 2 | 93 | AIO-Studien-gGmbHOTHER | 1 | Oct 1, 2025 | clinicaltrials |
| NCT03062358 | Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394) | completed | Phase 3 | 453 | Merck Sharp & Dohme LLCINDUSTRY | 5 | Sep 30, 2025 | clinicaltrials |
| NCT05052099 | Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer(COMBATBIL) | completed | Phase 1 / Phase 2 | 20 | University Hospital, EssenOTHER | 2 | Sep 29, 2025 | clinicaltrials |
| NCT06230328 | Brazilian Reality of Hepatocellular Carcinoma(BRA-HEP) | completed | — | 300 | AstraZenecaINDUSTRY | 1 | Sep 29, 2025 | clinicaltrials |
| NCT04487067 | A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista(AMETHISTA) | completed | Phase 3 | 152 | Hoffmann-La RocheINDUSTRY | 1 | Sep 22, 2025 | clinicaltrials |
| NCT06358001 | EchoTip AcuCore Post-Market Clinical Study | completed | — | 183 | Cook Research IncorporatedINDUSTRY | 1 | Sep 22, 2025 | clinicaltrials |
| NCT07184424 | Real-world Study of Lenalidomide After First-line Treatment Lenvatinib With PD-1 in Advanced HCC(Lenalidomide) | completed | N/A | 24 | Beijing Tsinghua Chang Gung HospitalOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT00976898 | Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer and Cholangiocarcinoma | completed | N/A | 83 | Massachusetts General HospitalOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT04264260 | Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment | completed | Phase 2 | 42 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT07160374 | ThinkRadial: A Prospective Study of Transradial deTACE in HCC Patients(ThinkRADIAL) | completed | — | 38 | Asan Medical CenterOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT04853017 | A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors(AMPLIFY-201) | completed | Phase 1 | 25 | Elicio TherapeuticsINDUSTRY | 1 | Sep 5, 2025 | clinicaltrials |
| NCT05197504 | Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Systemic Therapy(HCC) | completed | — | 166 | CHA UniversityOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT07157085 | AI Multitask Model for HCC Treatment | completed | — | 7,000 | Sun Yat-sen UniversityOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT03037437 | Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer | completed | Phase 2 | 64 | The University of Texas Health Science Center at San AntonioOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT05044065 | Blood Flow Restriction Exercise in Patients With Pancreatic, Biliary Tract, and Liver Cancer (PREV-Ex)(PREV-Ex) | completed | N/A | 52 | Karolinska InstitutetOTHER | 2 | Aug 27, 2025 | clinicaltrials |
| NCT07143955 | Dietary Intervention and Gut Microbiota in Hepatocellular Carcinoma (HCC) | completed | N/A | 100 | The First Hospital of Hebei Medical UniversityOTHER | 1 | Aug 27, 2025 | clinicaltrials |
| NCT04871321 | Biomarker Discovery in Patients With Advanced Biliary Tract Cancer | completed | — | 119 | CHA UniversityOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT03638141 | CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab | completed | Phase 2 | 21 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT03579771 | Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer | completed | Phase 2 | 30 | Emory UniversityOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06620510 | Retrospective Study of Long-Term Survival of "Immuncell-LC" in Patients Undergoing Curative Resection for HCC in Korea | completed | — | 230 | GC Cell CorporationINDUSTRY | 1 | Aug 15, 2025 | clinicaltrials |
| NCT02924376 | Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202) | completed | Phase 2 | 147 | Incyte CorporationINDUSTRY | 12 | Aug 14, 2025 | clinicaltrials |
| NCT04791176 | Phase II Study of Concurrent Lenvatinib and Radiotherapy for Advanced HCC | completed | Phase 2 | 64 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT03314935 | A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors | completed | Phase 1 / Phase 2 | 149 | Incyte CorporationINDUSTRY | 3 | Aug 12, 2025 | clinicaltrials |
| NCT04825834 | DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)(DELFI-L101) | completed | — | 2,992 | Delfi Diagnostics Inc.INDUSTRY | 2 | Aug 8, 2025 | clinicaltrials |
| NCT05678218 | Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma(POELH-II) | completed | — | 245 | Erasmus Medical CenterOTHER | 2 | Aug 8, 2025 | clinicaltrials |
| NCT02375880 | Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder | completed | Phase 1 | 51 | Leap Therapeutics, Inc.INDUSTRY | 1 | Aug 3, 2025 | clinicaltrials |
| NCT05430841 | Evaluating the Potential Usefulness of 18F-AlF-FAPI PET/CT in Patients With Gastrointestinal Tumors and Compared With 18F-FDG PET/CT | completed | N/A | 120 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT05616039 | I-FIGS Feasibility Study(I-FIGS) | completed | N/A | 42 | University Hospital Plymouth NHS TrustOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT07097220 | Effects of Different Anesthetic Techniques on Intraoperative and Postoperative Pain Levels and Cognitive Function in Patients Undergoing Hepatectomy for Liver Cancer | completed | N/A | 106 | Sir Run Run Shaw Hospital, Qingchun Campus, Zhejiang University School of Medicine,OTHER_GOV | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05292859 | Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs | completed | — | 7 | Alaunos TherapeuticsINDUSTRY | 1 | Jul 30, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Dec 10, 2025source: clinicaltrials