Subtype
Malignant Hepatobiliary Neoplasm
CI-CAN-00001136Explore in graph →
1,160 active trials17 approved drugs42 evidence items
- NCIt
- C8609
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Subtype
CI-CAN-00001136Explore in graph →
Clinical trials
5,029 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (561)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00441376 | A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver | completed | Phase 1 | 30 | ImunonINDUSTRY | 1 | Feb 7, 2019 | clinicaltrials |
| NCT00946153 | Study of Lenvatinib (E7080) in Participants With Advanced Hepatocellular Carcinoma (HCC) | completed | Phase 1 / Phase 2 | 66 | Eisai Co., Ltd.INDUSTRY | 2 | Feb 1, 2019 | clinicaltrials |
| NCT02053376 |
| A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy |
| completed |
| Phase 2 |
| 43 |
| Nathan Bahary, MDOTHER |
| 1 |
| Jan 30, 2019 |
| clinicaltrials |
| NCT02916199 | Primary Needle Knife Fistulotomy Versus Conventional Cannulation Method | completed | N/A | 207 | Gangnam Severance HospitalOTHER | 1 | Jan 30, 2019 | clinicaltrials |
| NCT01010126 | Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer | completed | Phase 2 | 252 | National Cancer Institute (NCI)NIH | 2 | Jan 25, 2019 | clinicaltrials |
| NCT01306058 | Sorafenib and TRC105 in Hepatocellular Cancer | completed | Phase 1 / Phase 2 | 27 | National Cancer Institute (NCI)NIH | 1 | Jan 23, 2019 | clinicaltrials |
| NCT02191878 | Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Intravenous TKM-080301 in Subjects With Advanced Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 43 | Arbutus Biopharma CorporationINDUSTRY | 6 | Jan 16, 2019 | clinicaltrials |
| NCT03358849 | Phase 1 Clinical Trial to Evaluate the Safety of Allogeneic NK Cell ("SMT-NK") Cell Therapy in Advanced Biliary Tract Cancer | completed | Phase 1 | 9 | Yonsei UniversityOTHER | 1 | Jan 16, 2019 | clinicaltrials |
| NCT01210495 | Axitinib For The Treatment Of Advanced Hepatocellular Carcinoma | completed | Phase 2 | 224 | PfizerINDUSTRY | 13 | Jan 9, 2019 | clinicaltrials |
| NCT03176485 | Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors | completed | N/A | 45 | University of ArizonaOTHER | 1 | Jan 4, 2019 | clinicaltrials |
| NCT01258608 | Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 101 | Human Genome Sciences Inc., a GSK CompanyINDUSTRY | 7 | Dec 19, 2018 | clinicaltrials |
| NCT02585856 | Efficacy and Safety of Photodynamic Therapy for Unresectable Cholangiocarcinoma | completed | N/A | 39 | First People's Hospital of HangzhouOTHER | 1 | Dec 19, 2018 | clinicaltrials |
| NCT03775863 | AFP Model and Liver Transplantation. | completed | — | 1,200 | Austral University, ArgentinaOTHER | 2 | Dec 19, 2018 | clinicaltrials |
| NCT00243841 | Dose Escalation Study for Primary Hepatocellular Carcinoma(SBF-HCC) | completed | N/A | 77 | Indiana UniversityOTHER | 1 | Dec 13, 2018 | clinicaltrials |
| NCT02073435 | A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation | completed | — | 177 | Northwestern UniversityOTHER | 1 | Dec 5, 2018 | clinicaltrials |
| NCT02069041 | A Study of Ramucirumab (LY3009806) in Participants With Advanced Liver Cancer | completed | Phase 1 | 8 | Eli Lilly and CompanyINDUSTRY | 1 | Nov 21, 2018 | clinicaltrials |
| NCT02649712 | Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction | completed | N/A | 72 | Xuzhou Central HospitalOTHER | 1 | Nov 20, 2018 | clinicaltrials |
| NCT02960594 | hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse(TRT-001) | completed | Phase 1 | 93 | Inovio PharmaceuticalsINDUSTRY | 1 | Nov 19, 2018 | clinicaltrials |
| NCT00827723 | Indocyanine Green and Portal Pressure in Viral and Alcoholic Cirrhotic Patients With Hepatocarcinoma | completed | — | 60 | University of Lausanne HospitalsOTHER | 1 | Nov 13, 2018 | clinicaltrials |
| NCT00004136 | Heat Therapy in Treating Patients With Unresectable Primary or Metastatic Liver Cancer | completed | Phase 2 | 59 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 6, 2018 | clinicaltrials |
| NCT01933945 | Outcomes of HCC (Hepatocellular Carcinoma) Patients Treated With TACE (Transarterial Chemoembolization) and Early, Not Early or Not at All Followed by Sorafenib(OPTIMIS) | completed | — | 1,676 | BayerINDUSTRY | 31 | Nov 6, 2018 | clinicaltrials |
| NCT02269995 | Post-marketing Surveillance of DC Bead in Patients With Hepatocellular Carcinoma | completed | — | 300 | Eisai Co., Ltd.INDUSTRY | 1 | Nov 5, 2018 | clinicaltrials |
| NCT00077142 | TAC-101 in Treating Patients With Advanced Hepatocellular Carcinoma (Liver Cancer) | completed | Phase 1 / Phase 2 | 37 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 31, 2018 | clinicaltrials |
| NCT02966509 | Engagement of Patients With Advanced Cancer(EPAC) | completed | N/A | 213 | Stanford UniversityOTHER | 0 | Oct 31, 2018 | clinicaltrials |
| NCT03595345 | A Worldwide Score for Hepatocellular Cancer and Liver Transplantation(TRAIN-SCORE) | completed | — | 3,100 | European Hepatocellular Cancer Liver Transplant GroupOTHER | 1 | Oct 29, 2018 | clinicaltrials |
| NCT03723304 | The Intention-to-treat Effect of Bridge Therapies in the Setting of Milan-in Patients | completed | — | 1,083 | European Hepatocellular Cancer Liver Transplant GroupOTHER | 1 | Oct 29, 2018 | clinicaltrials |
| NCT03299036 | Drug-loadable（T-ACE Beads）for Hepatoma Embolization Therapy | completed | N/A | 12 | National Cheng-Kung University HospitalOTHER | 1 | Oct 22, 2018 | clinicaltrials |
| NCT02833298 | Post Sustained Virological Response (SVR) Hepatocellular Carcinoma (HCC) Screening | completed | N/A | 25 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Oct 12, 2018 | clinicaltrials |
| NCT01360255 | AFP- L3% and DCP as Tumor Markers in Patients With Hepatocellular Carcinoma (HCC) Treated With Transarterial Chemoembolisation (TACE) | completed | — | 70 | University Hospital FreiburgOTHER | 1 | Oct 11, 2018 | clinicaltrials |
| NCT03698643 | Impact of New Interventional Imaging Modality Use on Patient Radiation Exposure in Transarterial Chemoembolization | completed | — | 145 | University Hospital, MontpellierOTHER | 1 | Oct 9, 2018 | clinicaltrials |
| NCT02181634 | Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinoma(PrE0204) | completed | Phase 2 | 74 | PrECOG, LLC.OTHER | 2 | Oct 3, 2018 | clinicaltrials |
| NCT01395030 | PET/CT in Diagnosing Patients With Liver Cancer Undergoing Surgical Resection | completed | Phase 2 | 64 | Queen's Medical CenterOTHER | 1 | Sep 26, 2018 | clinicaltrials |
| NCT01590732 | Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphoma | completed | Phase 1 | 22 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 19, 2018 | clinicaltrials |
| NCT00019474 | Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer | completed | Phase 2 | 60 | Montefiore Medical CenterOTHER | 1 | Sep 14, 2018 | clinicaltrials |
| NCT01409499 | Palliative Treatments for Patients With Advanced Hepatocellular Carcinoma (HCC)(2011PTAHCC) | completed | Phase 4 | 180 | Sun Yat-sen UniversityOTHER | 1 | Sep 11, 2018 | clinicaltrials |
| NCT00357422 | Comparison Study of Operation and PEIT for Small, Solitary Hepatocellular Carcinoma (HCC) | completed | N/A | 36 | Seoul National University HospitalOTHER | 1 | Sep 10, 2018 | clinicaltrials |
| NCT02433639 | Study of TH-302 Monotherapy as Second-line Treatment in Advanced Biliary Tract Cancer | completed | Phase 2 | 24 | Seoul National University HospitalOTHER | 1 | Sep 10, 2018 | clinicaltrials |
| NCT01273766 | Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies | completed | Phase 2 | 16 | Wake Forest University Health SciencesOTHER | 1 | Sep 7, 2018 | clinicaltrials |
| NCT02006030 | Ph 2 Trial of ADI PEG 20 Plus Concurrent Transarterial Chemoembolization (TACE) Vs TACE Alone in Patients With Unresectable Hepatocellular Carcinoma(TACE) | completed | Phase 2 | 30 | Polaris GroupINDUSTRY | 1 | Sep 4, 2018 | clinicaltrials |
| NCT01438554 | Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma | completed | Phase 1 | 89 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Aug 29, 2018 | clinicaltrials |
| NCT01643824 | Hypofractionated Proton Beam Radiotherapy for Hepatocellular Carcinoma | completed | N/A | 112 | National Cancer Center, KoreaOTHER_GOV | 1 | Aug 23, 2018 | clinicaltrials |
| NCT02321202 | Omega-3 Fatty Acid-Based Parenteral Nutrition Improves Postoperative Recovery for Cirrhotic Patients With Liver Cancer | completed | Phase 4 | 320 | Huazhong University of Science and TechnologyOTHER | 1 | Aug 22, 2018 | clinicaltrials |
| NCT03636620 | TACE Combined With RFA/MV Treatment in Hepatocellular Carcinoma Beyond Milan Criterial(TACE+RFA) | completed | Phase 3 | 110 | Fudan UniversityOTHER | 1 | Aug 17, 2018 | clinicaltrials |
| NCT01534637 | Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer | completed | Phase 2 | 22 | Wake Forest University Health SciencesOTHER | 1 | Aug 15, 2018 | clinicaltrials |
| NCT00692770 | Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)(STORM) | completed | Phase 3 | 1,114 | BayerINDUSTRY | 28 | Aug 8, 2018 | clinicaltrials |
| NCT02825550 | Taiwan ACE Beads for Hepatoma Embolization Therapy | completed | N/A | 13 | National Cheng-Kung University HospitalOTHER | 1 | Aug 7, 2018 | clinicaltrials |
| NCT02848638 | Pair Production PET Imaging to Detect Particle Distribution in Patients Undergoing Yttrium-90 Radioembolization(PET-Y90) | completed | — | 35 | University of WashingtonOTHER | 0 | Aug 2, 2018 | clinicaltrials |
| NCT01528878 | Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases | completed | N/A | 30 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jul 26, 2018 | clinicaltrials |
| NCT00293397 | Chemoembolization Using Doxorubicin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery | completed | N/A | 20 | Yale UniversityOTHER | 1 | Jul 18, 2018 | clinicaltrials |
| NCT01502410 | Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer | completed | Phase 2 | 20 | National Cancer Institute (NCI)NIH | 3 | Jun 26, 2018 | clinicaltrials |
Data updated 24 days agoSource updated Feb 7, 2019source: clinicaltrials