Clinical trial · Observational
A Worldwide Score for Hepatocellular Cancer and Liver Transplantation
A Worldwide Usable Scoring System for Patients With Hepatocellular Cancer Waiting for Liver Transplantation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The present study has been developed with multiple aims: 1) to refine available models for liver transplantation which would be able to cover the fate of HCC candidates from an ITT point of view; 2) to develop such an approach on cohorts coming from both Eastern and Western countries; 3) to maintain simplicity of use; 4) to provide individual prognostication taking into account different causes of death, through a competing-risk model; 5) to provide an external validation on cohorts coming from both Eastern and Western countries. All these aims converge at providing a comprehensive and useful assessment suitable for both candidates selection and allocation priority.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dropout, Patient | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Recurrence | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Liver transplantation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Training set
- description
- 2200 HCC cases from East and West centres enlisted for LT and then delisted or transplanted
- interventionNames
- Procedure: Liver transplantation
- label
- West validation set
- description
- 630 HCC cases from a Western centre enlisted for LT and then delisted or transplanted
- interventionNames
- Procedure: Liver transplantation
- label
- East validation set
- description
- 300 HCC cases from a Eastern centre enlisted for LT and then delisted or transplanted
- interventionNames
- Procedure: Liver transplantation
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All the adult ((≥18 years) patients enlisted for liver transplant with the radiological/histological diagnosis of hepatocellular cancer during the period 01/01/2000-31/03/2017 Exclusion Criteria: * Mixed hepatocellular-cholangiocellular * Cholangiocellular cancer misdiagnosed as HCC * Post-LT incidental HCC. * Patients enlisted before 01/01/2000
References
Publications (0)
Data not yet available