Subtype
Malignant Hepatobiliary Neoplasm
CI-CAN-00001136Explore in graph →
1,160 active trials17 approved drugs42 evidence items
- NCIt
- C8609
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Subtype
CI-CAN-00001136Explore in graph →
Clinical trials
5,029 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (561)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05640960 | Undifferentiated Embryonal Sarcoma of the Liver: Evaluation of the Relapse Profile According to the Therapies Administered(SARCOM) | completed | — | 30 | University Hospital, Strasbourg, FranceOTHER | 1 | Dec 8, 2023 | clinicaltrials |
| NCT00355238 | A Phase II Open Label Study of BMS-582664 in Locally Advanced or Metastatic Hepatocellular Cancer | completed | Phase 2 | 137 | Bristol-Myers SquibbINDUSTRY | 8 | Dec 1, 2023 |
| clinicaltrials |
| NCT03796429 | A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer | completed | Phase 2 | 50 | Shanghai Zhongshan HospitalOTHER | 1 | Nov 29, 2023 | clinicaltrials |
| NCT05498779 | Ablation of Hepatocellular Carcinoma: a Nationwide Study | completed | — | 490 | Rigshospitalet, DenmarkOTHER | 1 | Nov 28, 2023 | clinicaltrials |
| NCT03531320 | Study of D07001-Softgel Capsules in Subjects With Gastrointestinal Cancer in Dose-Escalation Phase and in Subjects With Biliary Tract Cancer in Dose-Expansion Phase | completed | Phase 1 / Phase 2 | 19 | InnoPharmax Inc.INDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT01447667 | Magnetic Resonance Elastography (MRE) as a Predictor of HCC Recurrence After Radiofrequency Ablation (RFA)(MRE) | completed | N/A | 72 | Seoul National University HospitalOTHER | 1 | Nov 22, 2023 | clinicaltrials |
| NCT01523223 | Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies | completed | Phase 1 | 16 | Robert LowskyOTHER | 1 | Nov 22, 2023 | clinicaltrials |
| NCT01910909 | Stereotactic Body Radiotherapy for Unresectable Hepatocellular Carcinoma(SBRT for HCC) | completed | N/A | 56 | Samsung Medical CenterOTHER | 1 | Nov 22, 2023 | clinicaltrials |
| NCT00866957 | Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC) | completed | — | 180 | Northwestern UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT04391348 | Combination PET With 18F-fluorodeoxyglucose (18F-FDG) and 18 F-choline in Patient With HCC(PET-HCC01) | completed | N/A | 230 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT04596865 | Recurrence After Whipple's (RAW) Study | completed | — | 1,484 | University Hospital Plymouth NHS TrustOTHER | 8 | Nov 18, 2023 | clinicaltrials |
| NCT05183776 | Clinical Validation of a Fractional Administration Device for Holmium-166 SIRT(CONTROL) | completed | N/A | 5 | Radboud University Medical CenterOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT02279719 | A Study of BBI608 in Combination With Sorafenib, or BBI503 in Combination With Sorafenib in Adult Patients With Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 97 | Sumitomo Pharma America, Inc.INDUSTRY | 1 | Nov 15, 2023 | clinicaltrials |
| NCT02460835 | A Pilot Study of Individualized Adaptive Radiation Therapy for Hepatocellular Carcinoma | completed | N/A | 77 | University of Michigan Rogel Cancer CenterOTHER | 1 | Nov 15, 2023 | clinicaltrials |
| NCT04297254 | A Study to Assess the Safety and Efficacy of Lenvatinib as First-line Treatment in Participants With Unresectable HCC | completed | Phase 4 | 50 | Eisai Pharmaceuticals India Pvt. LtdINDUSTRY | 1 | Nov 15, 2023 | clinicaltrials |
| NCT02232633 | A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancer | completed | Phase 2 | 45 | Sumitomo Pharma America, Inc.INDUSTRY | 1 | Nov 14, 2023 | clinicaltrials |
| NCT02834780 | Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma | completed | Phase 1 | 128 | H3 Biomedicine Inc.INDUSTRY | 11 | Nov 13, 2023 | clinicaltrials |
| NCT00716976 | Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy | completed | Phase 3 | 131 | Children's Oncology GroupNETWORK | 3 | Nov 9, 2023 | clinicaltrials |
| NCT01556490 | Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer(STOP-HCC) | completed | N/A | 526 | Boston Scientific CorporationINDUSTRY | 11 | Nov 8, 2023 | clinicaltrials |
| NCT03260712 | Pembrolizumab in Biliary Tract Cancer | completed | Phase 2 | 50 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 3 | Nov 3, 2023 | clinicaltrials |
| NCT04569799 | Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post TACE(TACE) | completed | Phase 4 | 26 | Milton S. Hershey Medical CenterOTHER | 1 | Nov 2, 2023 | clinicaltrials |
| NCT03833661 | M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer) | completed | Phase 2 | 159 | EMD Serono Research & Development Institute, Inc.INDUSTRY | 9 | Oct 25, 2023 | clinicaltrials |
| NCT03434379 | A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma(IMbrave150) | completed | Phase 3 | 558 | Hoffmann-La RocheINDUSTRY | 17 | Oct 23, 2023 | clinicaltrials |
| NCT01401907 | Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies | completed | N/A | 351 | Massachusetts General HospitalOTHER | 1 | Oct 19, 2023 | clinicaltrials |
| NCT04534309 | Behavioral Weight Loss Program for Cancer Survivors in Maryland(ASPIRE) | completed | N/A | 340 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 10, 2023 | clinicaltrials |
| NCT03735628 | An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors | completed | Phase 1 | 16 | BayerINDUSTRY | 2 | Oct 6, 2023 | clinicaltrials |
| NCT03756597 | PAN-study: Pan-Cancer Early Detection Study (PAN) | completed | — | 268 | Owlstone LtdINDUSTRY | 1 | Oct 5, 2023 | clinicaltrials |
| NCT01336933 | Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma | completed | Phase 2 | 34 | University of NebraskaOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT02866383 | Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients(CheckPAC) | completed | Phase 2 | 160 | Herlev HospitalOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT03207347 | A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001) | completed | Phase 2 | 37 | University of FloridaOTHER | 1 | Sep 15, 2023 | clinicaltrials |
| NCT05930119 | HMPL-453 Food Effect and PPI Study in Healthy Volunteer Study | completed | Phase 1 | 24 | HutchmedINDUSTRY | 1 | Sep 6, 2023 | clinicaltrials |
| NCT04555265 | Cytokine Change in Hepatocellular Carcinoma Treated by Thermal Ablation | completed | N/A | 60 | Chinese University of Hong KongOTHER | 1 | Aug 31, 2023 | clinicaltrials |
| NCT03702998 | Hepatocellular Carcinoma in HIV-infected Individuals in Asian Population | completed | — | 3,900 | Chinese University of Hong KongOTHER | 1 | Aug 30, 2023 | clinicaltrials |
| NCT04942665 | Low Dose ICG for Biliary Tract and Tumor Imaging(ICG) | completed | Phase 2 | 60 | University of FloridaOTHER | 1 | Aug 30, 2023 | clinicaltrials |
| NCT06013657 | Surgical Resection for Hepatocellular Carcinoma | completed | — | 91 | Dr Cipto Mangunkusumo General HospitalOTHER | 1 | Aug 28, 2023 | clinicaltrials |
| NCT06013774 | Interventional X-ray and Scintigraphy Imaging of 99mTc-MAA During the Radioembolisation Pretreatment Procedure(IXSI) | completed | N/A | 12 | UMC UtrechtOTHER | 1 | Aug 28, 2023 | clinicaltrials |
| NCT04920019 | Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery | completed | N/A | 140 | Mahidol UniversityOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT06005883 | Surgical Outcome of HCC With Portal Vein Tumor Thrombosis on the Basis of Risk Scoring | completed | — | 332 | Keimyung University Dongsan Medical CenterOTHER | 1 | Aug 23, 2023 | clinicaltrials |
| NCT03003065 | Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct Cancers(PDT) | completed | Phase 2 | 10 | Chinese University of Hong KongOTHER | 1 | Aug 22, 2023 | clinicaltrials |
| NCT00539643 | Trial of Beads Versus Doxorubicin Eluting Beads for Arterial Embolization of Hepatocellular Carcinoma | completed | Phase 2 | 101 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 18, 2023 | clinicaltrials |
| NCT03009201 | Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery | completed | Phase 1 | 16 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 16, 2023 | clinicaltrials |
| NCT05989789 | Radioactive Seed-guided Resection of Cholangiocellular Carcinoma in Cirrhotic Patients | completed | N/A | 2 | Clarunis - Universitäres Bauchzentrum BaselOTHER | 1 | Aug 14, 2023 | clinicaltrials |
| NCT04072445 | Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer | completed | Phase 2 | 28 | Mayo ClinicOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT05643391 | Safety and Feasibility of Radioembolization Using Ho-166 in Patients With Unresectable Hepatocellular Carcinoma(RETOUCH) | completed | N/A | 20 | Erasme University HospitalOTHER | 1 | Aug 8, 2023 | clinicaltrials |
| NCT00095992 | SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer | completed | Phase 2 | 15 | NCIC Clinical Trials GroupNETWORK | 1 | Aug 4, 2023 | clinicaltrials |
| NCT03602079 | Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene | completed | Phase 1 / Phase 2 | 49 | Klus Pharma Inc.INDUSTRY | 1 | Aug 3, 2023 | clinicaltrials |
| NCT04034238 | Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Aug 1, 2023 | clinicaltrials |
| NCT04642547 | Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma | completed | N/A | 30 | RenJi HospitalOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05291338 | Pharmacogenetic Study in Hepatocellular Carcinoma Patients. | completed | — | 107 | Rehab WeridaOTHER | 1 | Jul 28, 2023 | clinicaltrials |
| NCT03347292 | Regorafenib Plus Pembrolizumab in First Line Systemic Treatment of HCC | completed | Phase 1 | 58 | BayerINDUSTRY | 2 | Jul 25, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Dec 8, 2023source: clinicaltrials