Clinical trial · Observational
Hepatocellular Carcinoma in HIV-infected Individuals in Asian Population
Incidence and Mortality of Hepatocellular Carcinoma in HIV-infected Individuals in an Asian Population
NCT03702998CI-TRIAL-00069189completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a retrospective study, all HIV-infected individuals followed up at the three designated HIV clinics in Hong Kong with and without HBV and/or HCV co-infection will be included in the analysis. The incidence and mortality of HCC among HIV-infected individuals with and without HBV/HCV co-infection in an Asian population will be determined.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatitis B | — | UNRESOLVED | — |
| Hepatitis C | — | UNRESOLVED | — |
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
| HIV Infections | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- HIV-infected individuals +/- HBV/ HCV
- description
- 1 All HIV-infected individuals followed up in all public HIV clinics with and without HBV and/or HCV co-infection will be included in the analysis. 1.1 Inclusion criteria for HIV-infected individuals with and without HBV or HCV co-infection: 1.1.1 Positive HIV antibody 1.1.2 At least one visit in one of the HIV clinics 1.1.3 Subjects with positive HBsAg and/or anti-HBc will be regarded as having HBV co-infection 1.1.4 Subjects with positive HCV antibody will be regarded as having HCV co-infection
- label
- HBV/HCV mono-infected individuals
- description
- 2 All HBV and/or HCV-infected individuals followed up in public hospitals will be identified from the Hospital Authority electronic database. 2.1 Inclusion criteria for HBV/HCV mono-infected individuals 2.1.1 Documented diagnosis of hepatitis B or hepatitis C infection, or 2.1.2 Positive HBsAg and/or anti-HBc, or 2.1.3 Positive HCV antibody, and 2.1.4 Negative HIV antibody result, or no record of HIV diagnosis or anti-retroviral therapy prescription
Primary outcomes (1)
- measure
- Incidence of HCC
- timeFrame
- From the time of diagnosis up to 20 years of follow up.
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
1. HIV-infected individuals with and without HBV or HCV co-infection: Inclusion criteria: * Positive HIV antibody * At least one visit in one of the HIV clinics * Subjects with positive HBsAg and/or anti-HBc will be regarded as having HBV co-infection * Subjects with positive HCV antibody will be regarded as having HCV co-infection Exclusion criteria: -nil 2. HBV/HCV mono-infected individuals: Inclusion criteria: * Documented diagnosis of hepatitis B or hepatitis C infection, or * Positive HBsAg and/or anti-HBc, or * Positive HCV antibody, and * Negative HIV antibody result, or no record of HIV diagnosis or anti-retroviral therapy prescription Exclusion criteria: \- nil
References
Publications (0)
Data not yet available
No reference posted for this study.