Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01217060 | Trimodality Management of T1b Esophageal Cancers | completed | Phase 1 / Phase 2 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 13, 2021 | clinicaltrials |
| NCT02128243 | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer(MATEO) | completed | Phase 2 | 242 | AIO-Studien-gGmbHOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT02645864 |
| Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma |
| completed |
| Phase 1 |
| 12 |
| Peking UniversityOTHER |
| 1 |
| Mar 18, 2021 |
| clinicaltrials |
| NCT03541629 | Audit of the Spanish EURECCA Esophagogastric Cancer Registry | completed | — | 1,839 | Parc de Salut MarOTHER | 1 | Mar 16, 2021 | clinicaltrials |
| NCT03719716 | Early Support in Primary Care for People Starting Treatment for Cancer(GI-ACP) | completed | N/A | 46 | NHS LothianOTHER_GOV | 1 | Mar 9, 2021 | clinicaltrials |
| NCT02055313 | Perceptions of Exceptional Patients in Cancer Care Relating to Their Unusual Survival | completed | — | 20 | Meir Medical CenterOTHER | 0 | Feb 25, 2021 | clinicaltrials |
| NCT03115541 | Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection | completed | — | 187 | McMaster UniversityOTHER | 3 | Feb 24, 2021 | clinicaltrials |
| NCT00002883 | Surgery With or Without Combination Chemotherapy in Treating Patients With Cancer of the Esophagus | completed | Phase 3 | 250 | UNICANCEROTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT04764240 | Precisely Estimation of the Prognostic Value of Lymph Node in ESCC | completed | — | 3,700 | Shanghai Cancer Hospital, ChinaOTHER | 0 | Feb 23, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT01463605 | Nimotuzumab Combined With Radiotherapy for Older Patients With Esophageal Cancer: a Single, Non-control Clinical Trial | completed | Phase 2 | 46 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT03116152 | Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment | completed | Phase 2 | 190 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Feb 3, 2021 | clinicaltrials |
| NCT04225364 | Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 56 | Guangzhou Institute of Respiratory DiseaseOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT01183559 | A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery | completed | Phase 1 | 9 | Fox Chase Cancer CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT01766986 | Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction | completed | — | 130 | Universitätsklinikum Hamburg-EppendorfOTHER | 0 | Jan 6, 2021 | clinicaltrials |
| NCT04683601 | Generation of a Surgical Field in the Left Lateral Decubitus Position | completed | — | 154 | Shizuoka Cancer CenterOTHER | 0 | Dec 24, 2020 | clinicaltrials |
| NCT03082586 | Radiation Dose Escalation in Esophageal Cancer | completed | N/A | 31 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Dec 22, 2020 | clinicaltrials |
| NCT01598077 | A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer | completed | Phase 1 | 54 | Novartis PharmaceuticalsINDUSTRY | 5 | Dec 19, 2020 | clinicaltrials |
| NCT01822613 | Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) | completed | Phase 1 | 48 | Novartis PharmaceuticalsINDUSTRY | 9 | Dec 19, 2020 | clinicaltrials |
| NCT02375958 | PCA062 in pCAD-positive Tumors. | completed | Phase 1 | 47 | Novartis PharmaceuticalsINDUSTRY | 6 | Dec 19, 2020 | clinicaltrials |
| NCT00339742 | Stomach and Esophageal Cancers in Northern Iran | completed | — | 1,163 | National Cancer Institute (NCI)NIH | 1 | Dec 11, 2020 | clinicaltrials |
| NCT00342472 | Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China | completed | — | 81 | National Cancer Institute (NCI)NIH | 1 | Dec 11, 2020 | clinicaltrials |
| NCT02890979 | Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease | completed | N/A | 11 | OHSU Knight Cancer InstituteOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT02125448 | PReoperative Identification Of Response to Neoadjuvant Chemoradiotherapy for Esophageal Cancer(PRIOR) | completed | — | 30 | Gert MeijerOTHER | 2 | Nov 16, 2020 | clinicaltrials |
| NCT03538028 | A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies | completed | Phase 1 | 22 | Incyte Biosciences International SàrlINDUSTRY | 1 | Oct 30, 2020 | clinicaltrials |
| NCT01107639 | Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | completed | Phase 3 | 297 | Swiss Cancer InstituteOTHER | 5 | Oct 20, 2020 | clinicaltrials |
| NCT02813967 | S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer | completed | Phase 3 | 298 | Zhejiang Cancer HospitalOTHER | 1 | Sep 16, 2020 | clinicaltrials |
| NCT02606916 | Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer. | completed | Phase 2 | 42 | Sun Yat-sen UniversityOTHER | 1 | Sep 4, 2020 | clinicaltrials |
| NCT03413436 | Lobaplation or Cisplatin in Adjuvant Chemotherapy for Esophageal Carcinoma | completed | Phase 4 | 733 | Henan Cancer HospitalOTHER_GOV | 1 | Aug 28, 2020 | clinicaltrials |
| NCT02658214 | Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors | completed | Phase 1 | 32 | AstraZenecaINDUSTRY | 2 | Aug 20, 2020 | clinicaltrials |
| NCT03187314 | Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer | completed | Phase 2 | 25 | Hangzhou Cancer HospitalOTHER | 1 | Aug 17, 2020 | clinicaltrials |
| NCT00985192 | Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer | completed | Phase 2 | 49 | Translational Oncology Research InternationalOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT00003748 | Irinotecan in Treating Patients With Esophageal or Stomach Cancer | completed | Phase 2 | 40 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00020761 | Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach | completed | Phase 2 | 51 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00020787 | Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer | completed | Phase 3 | 8 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00727376 | Evaluation of Polyflex Stenting in Esophageal Cancer Patients | completed | — | 26 | University of LouisvilleOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT02744729 | 99mTc-3PRGD2 SPECT/CT in Esophagus Cancer Patients | completed | Early Phase 1 | 29 | First Affiliated Hospital of Fujian Medical UniversityOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00898495 | Genes in Predicting Outcome in Patients With Esophageal Cancer Treated With Cisplatin, Radiation Therapy, and Surgery | completed | — | 118 | ECOG-ACRIN Cancer Research GroupNETWORK | 0 | Jul 31, 2020 | clinicaltrials |
| NCT03032224 | Analysis of Body Composition in Relation to Outcome After Surgery in a Cohort of Patients With Esophageal Cancer | completed | — | 76 | Vastra Gotaland RegionOTHER_GOV | 1 | Jul 28, 2020 | clinicaltrials |
| NCT03066167 | Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer | completed | — | 64 | Vastra Gotaland RegionOTHER_GOV | 1 | Jul 28, 2020 | clinicaltrials |
| NCT02120911 | Feasibility Study of Chemoradiation, TRAstuzumab and Pertuzumab in Resectable HER2+ Esophageal Carcinoma(TRAP) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jul 1, 2020 | clinicaltrials |
| NCT02138929 | LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma | completed | Phase 1 | 25 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT01102088 | Simultaneous Integrated Boost (SIB) in Esophageal Cancer | completed | Phase 1 | 61 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2020 | clinicaltrials |
| NCT02047305 | Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia | completed | N/A | 96 | Covidien, GI SolutionsINDUSTRY | 1 | May 21, 2020 | clinicaltrials |
| NCT03418298 | Prehabilitation in Patients With Esophageal or Gastric Cancers | completed | N/A | 30 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | May 21, 2020 | clinicaltrials |
| NCT01913639 | FOLFOX Plus Regorafenib in Patients With Unresectable or Metastatic Esophagogastric Cancer | completed | Phase 2 | 39 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT02964455 | Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Sun Yat-sen UniversityOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT03087864 | PDL-1 Targeting in Resectable Oesophageal Cancer(PERFECT) | completed | Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | May 11, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Apr 13, 2021source: clinicaltrials