Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03416244 | A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer(RAMONA) | completed | Phase 2 | 66 | AIO-Studien-gGmbHOTHER | 1 | Sep 29, 2022 | clinicaltrials |
| NCT02513784 | Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome(Mouthwash) | completed | N/A | 20 | Columbia UniversityOTHER | 1 |
| Sep 22, 2022 |
| clinicaltrials |
| NCT04609813 | Esophageal cAncer Screening Trial(EAST) | completed | — | 14,597 | Changhai HospitalOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT02559687 | Study of Pembrolizumab (MK-3475) in Previously-Treated Participants With Advanced Carcinoma of the Esophagus or Esophagogastric Junction (MK-3475-180/KEYNOTE-180) | completed | Phase 2 | 121 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 14, 2022 | clinicaltrials |
| NCT01212822 | Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer | completed | Phase 2 | 20 | Fox Chase Cancer CenterOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT03662204 | Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors | completed | — | 5,133 | Exact Sciences CorporationINDUSTRY | 1 | Sep 1, 2022 | clinicaltrials |
| NCT04005170 | Combination of Toripalimab and Chemoradiotherapy in Esophageal Cancer | completed | Phase 2 | 42 | Mian XIOTHER | 1 | Aug 23, 2022 | clinicaltrials |
| NCT05499195 | Adjuvant Radiotherapy for pT1b Esophageal Cancer After Submucosal Endoscopic Resection | completed | — | 159 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 12, 2022 | clinicaltrials |
| NCT01780961 | Esophageal Cancer Tissue Banking(ESBX) | completed | — | 311 | Washington University School of MedicineOTHER | 1 | Aug 9, 2022 | clinicaltrials |
| NCT03925870 | KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 45 | Jiangsu Alphamab Biopharmaceuticals Co., LtdINDUSTRY | 1 | Aug 5, 2022 | clinicaltrials |
| NCT04545632 | Docetaxel Ethanol-induced Symptoms; The Incidence and Risk Forecating Factor(DETECT) | completed | — | 458 | Boryung Pharmaceutical Co., LtdINDUSTRY | 1 | Jul 27, 2022 | clinicaltrials |
| NCT02569242 | Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer | completed | Phase 3 | 419 | Ono Pharmaceutical Co., Ltd.INDUSTRY | 8 | Jul 6, 2022 | clinicaltrials |
| NCT04251312 | Minimizing Pathologic Aspiration in Patients Undergoing Esophageal and Lung Resections for Cancer | completed | N/A | 49 | University of Mississippi Medical CenterOTHER | 1 | Jun 23, 2022 | clinicaltrials |
| NCT00655876 | Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer | completed | Phase 3 | 344 | Radiation Therapy Oncology GroupNETWORK | 2 | Jun 14, 2022 | clinicaltrials |
| NCT03335813 | Endoesophageal Brachytherapy for Patients With Esophageal Cancer | completed | N/A | 7 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 9, 2022 | clinicaltrials |
| NCT03816748 | The Efficacy of Postoperative Application of HFNC at Acute Phase for Minimally Invasive Esophagectomy Surgery Patients | completed | N/A | 69 | National Taiwan University HospitalOTHER | 1 | Jun 1, 2022 | clinicaltrials |
| NCT03365791 | PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies | completed | Phase 2 | 76 | Novartis PharmaceuticalsINDUSTRY | 1 | May 27, 2022 | clinicaltrials |
| NCT04936399 | A Study of Participants With Squamous Cell Oesophageal Carcinoma Receiving Nivolumab as Part of an Early Access to Medicines Scheme (EAMS) Program in the United Kingdom | completed | — | 87 | Bristol-Myers SquibbINDUSTRY | 1 | May 25, 2022 | clinicaltrials |
| NCT03409848 | Ipilimumab or FOLFOX in Combination With Nivolumab and Trastuzumab in HER2 Positive EsophagoGastric Adenocarcinoma(INTEGA) | completed | Phase 2 | 97 | AIO-Studien-gGmbHOTHER | 1 | May 18, 2022 | clinicaltrials |
| NCT01293448 | Evaluation of Balloon-based Cryoablation of Human Esophageal Epithelium | completed | N/A | 21 | Pentax MedicalINDUSTRY | 2 | Apr 28, 2022 | clinicaltrials |
| NCT02729727 | Clinical Study to Evaluate CryoBalloon™ Ablation System in Patients Undergoing Esophagectomy | completed | N/A | 3 | Pentax MedicalINDUSTRY | 1 | Apr 28, 2022 | clinicaltrials |
| NCT04316078 | A Novel Patient Engagement Platform Among Patients With Gastrointestinal Malignancies | completed | N/A | 126 | Sheba Medical CenterOTHER_GOV | 1 | Apr 28, 2022 | clinicaltrials |
| NCT02729753 | Clinical Study to Evaluate CryoBalloon™ Full and Swipe Ablation Systems for Ablation of Human Esophageal Epithelium | completed | N/A | 10 | Pentax MedicalINDUSTRY | 1 | Apr 22, 2022 | clinicaltrials |
| NCT00831571 | Prospective Analysis of Hypersensitivity Reactions to Oxaliplatin | completed | — | 112 | Dana-Farber Cancer InstituteOTHER | 1 | Apr 18, 2022 | clinicaltrials |
| NCT03829098 | TreatmENT of AnastomotiC Leakage After Esophagectomy(TENTACLE) | completed | — | 1,509 | Radboud University Medical CenterOTHER | 1 | Apr 1, 2022 | clinicaltrials |
| NCT01137123 | Improve the Treatment of Thoracic Esophageal Cancer | completed | Phase 3 | 301 | Sun Yat-sen UniversityOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT04822103 | A Real-World Study of Immune Checkpoint Inhibitors and Chemotherapy for Advanced Esophageal Cancer | completed | — | 155 | Guangdong Provincial People's HospitalOTHER | 1 | Mar 18, 2022 | clinicaltrials |
| NCT00393068 | Chemotherapy, Radiation Therapy and Immunotherapy Prior to Surgery in Operable Esophageal Cancer | completed | Phase 2 | 62 | SCRI Development Innovations, LLCOTHER | 1 | Mar 2, 2022 | clinicaltrials |
| NCT02459457 | A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer | completed | Phase 3 | 321 | Fudan UniversityOTHER | 1 | Feb 9, 2022 | clinicaltrials |
| NCT01077817 | Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352) | completed | — | 684,815 | Organon and CoINDUSTRY | 0 | Feb 3, 2022 | clinicaltrials |
| NCT00967577 | 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors | completed | Phase 1 | 20 | Weill Medical College of Cornell UniversityOTHER | 1 | Feb 2, 2022 | clinicaltrials |
| NCT04316689 | First-in-human Study of S-588210 (S-488210+S-488211) | completed | Phase 1 | 10 | ShionogiINDUSTRY | 1 | Jan 26, 2022 | clinicaltrials |
| NCT03652077 | A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies | completed | Phase 1 | 40 | Incyte CorporationINDUSTRY | 1 | Nov 15, 2021 | clinicaltrials |
| NCT04196075 | The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer(AP) | completed | Phase 3 | 30 | Chinese University of Hong KongOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT03008980 | WATS3D for the Detection of Esophageal Dysplasia | completed | — | 160 | CDx DiagnosticsINDUSTRY | 1 | Nov 4, 2021 | clinicaltrials |
| NCT03799380 | DRIHNC - Dehydration Reduction in Head & Neck Cancer | completed | N/A | 41 | Case Comprehensive Cancer CenterOTHER | 1 | Nov 3, 2021 | clinicaltrials |
| NCT05088304 | GLIM-defined Malnutrition Criteria for Postoperative Outcomes in Patients With Esophagogastric Cancer | completed | — | 205 | Jinling Hospital, ChinaOTHER | 0 | Oct 21, 2021 | clinicaltrials |
| NCT03095209 | Observation Study of Patients With Non-Small Cell Lung Cancer and Esophageal Cancer Treated With Chemo-Radiation Followed by Surgery | completed | — | 6 | Fox Chase Cancer CenterOTHER | 1 | Oct 12, 2021 | clinicaltrials |
| NCT00591123 | Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia | completed | Phase 2 | 38 | Translational Oncology Research InternationalOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT00381706 | Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer | completed | Phase 2 | 245 | Alliance for Clinical Trials in OncologyOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT04090554 | Cytosponge™ Feasibility Study in Tanzania(CytoSCCAPE) | completed | N/A | 101 | International Agency for Research on CancerOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT03529266 | Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma.(PLACE020) | completed | Phase 2 | 57 | Sun Yat-sen UniversityOTHER | 1 | Aug 24, 2021 | clinicaltrials |
| NCT03734627 | Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery(EndoGut) | completed | — | 40 | St. James's Hospital, IrelandOTHER | 1 | Aug 16, 2021 | clinicaltrials |
| NCT01631552 | Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer | completed | Phase 1 / Phase 2 | 515 | Gilead SciencesINDUSTRY | 1 | Aug 12, 2021 | clinicaltrials |
| NCT01558648 | Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer | completed | — | 257 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 6, 2021 | clinicaltrials |
| NCT02452021 | Pencil Beam Scanning Proton Radiotherapy for Esophageal Cancer | completed | — | 30 | Mayo ClinicOTHER | 1 | Jul 27, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04669951 | Urokinase-type Plasminogen Activator Receptor and Gastroesophageal Cancer | completed | N/A | 100 | Michael Patrick AchiamOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT03151642 | A PILOT STUDY OF DIFFUSION WEIGHTED MRI TO ASSESS ESOPHAGEAL TUMOR RESONSE TO NEOADJUVANT CHEMORADIATION | completed | — | 11 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 26, 2021 | clinicaltrials |
| NCT01077999 | Chemoradiation and Panitumumab for Esophageal Cancer | completed | Phase 2 | 78 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Apr 21, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Sep 29, 2022source: clinicaltrials