Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04796025 | TACE Combined With Sintilimab Plus Bevacizumab Biosimilar in Hepatocellular Carcinoma (BCLC-C Stage ): a Prospective Single-arm Phase II Clinical Study(T-Double) | unknown | Phase 2 | 34 | Sun Yat-sen UniversityOTHER | 1 | Sep 28, 2021 | clinicaltrials |
| NCT04490694 | TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma | unknown | Phase 2 | 54 | Shanghai Zhongshan HospitalOTHER | 1 | Sep 24, 2021 |
| clinicaltrials |
| NCT04814043 | PD-1 Antibody and Lenvatinib Plus TACE-HAIC for Potential Resectable HCC: a Single-arm, Phase 2 Clinical Trial(PLATIC) | unknown | Phase 2 | 57 | Sun Yat-sen UniversityOTHER | 1 | Sep 22, 2021 | clinicaltrials |
| NCT02948348 | Study to Nivolumab Following Preoperative Chemoradiotherapy | unknown | Phase 1 / Phase 2 | 90 | Takayuki YoshinoOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT05044728 | Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest. | unknown | Phase 2 | 80 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Sep 16, 2021 | clinicaltrials |
| NCT05042336 | The Effectiveness and Safety of Camrelizumab/Lenvatinib Combined With TACE in Patients With Borderline Resectable HCC | unknown | Phase 1 / Phase 2 | 49 | Sichuan UniversityOTHER | 1 | Sep 13, 2021 | clinicaltrials |
| NCT03800953 | The Ave-CRT Study for Newly Diagnosed Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 26 | National Taiwan University HospitalOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT04724226 | Cryoablation Combined With Camrelizumab and Apatinib in Advanced Hepatocellular Carcinoma(C-couple) | unknown | Phase 2 | 34 | Sun Yat-sen UniversityOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT05035914 | Anlotinib Combined With mXELIRI as Second-line Treatment of Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 94 | Guangzhou University of Traditional Chinese MedicineOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT03387904 | Study of Anlotinib Plus Irinotecan in Patients With Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 120 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Sep 2, 2021 | clinicaltrials |
| NCT03603834 | Neoadjuvant mFOLFOXIRI for Potentially Resectable Cholangiocarcinoma | unknown | Phase 2 | 25 | Khon Kaen UniversityOTHER | 1 | Sep 1, 2021 | clinicaltrials |
| NCT05030246 | Trial of Surufatinib Combined With Toripalimab in the Treatment of Peritoneal Metastatic Carcinoma of Gastrointestinal or Primary Peritoneal Cancer | unknown | Phase 2 | 72 | Peking UniversityOTHER | 1 | Sep 1, 2021 | clinicaltrials |
| NCT04982939 | Peri-operative Sintilimab in Combination With SOX in Locally Advanced Gastric Cancer | unknown | Phase 2 | 210 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Aug 31, 2021 | clinicaltrials |
| NCT03126071 | Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer | unknown | Phase 2 | 100 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04241731 | A Study of Cetuximab Plus Raltitrexed for Maintenance Treatment in Advanced Colorectal Cancer | unknown | Phase 2 | 50 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04324476 | A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer | unknown | Phase 2 | 50 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04948034 | The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE) | unknown | Phase 2 | 68 | Fudan UniversityOTHER | 1 | Aug 27, 2021 | clinicaltrials |
| NCT04514835 | A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC | unknown | Phase 2 | 44 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT04063683 | Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma(ESCC). | unknown | Phase 2 | 47 | Henan Cancer HospitalOTHER_GOV | 1 | Aug 24, 2021 | clinicaltrials |
| NCT04526470 | Alpelisib and Paclitaxel in PIK3CA-altered Gastric Cancer | unknown | Phase 1 / Phase 2 | 55 | Seoul National University Bundang HospitalOTHER | 1 | Aug 24, 2021 | clinicaltrials |
| NCT05002686 | Safety and Efficacy of Sintilimab in Combination With Chemoradiothrapy Followed by D2 Surgical Resection in Patients With Advanced Gastric Cancer With Retroperitoneal Lymph Node Metastasis | unknown | Phase 2 / Phase 3 | 60 | Ruijin HospitalOTHER | 1 | Aug 24, 2021 | clinicaltrials |
| NCT04466254 | Efficacy and Safety Study of Combination of CPGJ602 and Chemotherapy, in First Line, With Wild KRAS/NRAS/BRAF in Metastatic Colorectal Cancer | unknown | Phase 2 | 75 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Aug 23, 2021 | clinicaltrials |
| NCT04533490 | A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 42 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Aug 23, 2021 | clinicaltrials |
| NCT04888403 | Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Aug 23, 2021 | clinicaltrials |
| NCT03727763 | Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT) | unknown | Phase 2 | 30 | Shanghai Changzheng HospitalOTHER | 1 | Aug 19, 2021 | clinicaltrials |
| NCT04718701 | Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer(ATNPA) | unknown | Phase 2 | 53 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Aug 16, 2021 | clinicaltrials |
| NCT02305186 | Safety and Immunological Effect of Pembrolizumab in Resectable or Borderline Resectable Pancreatic Cancer(UVA-PC-PD101) | unknown | Phase 1 / Phase 2 | 68 | Craig L Slingluff, JrOTHER | 1 | Aug 13, 2021 | clinicaltrials |
| NCT04994236 | Hepatic Artery Infusion Chemotherapy for Unresectable Hepatocelluar Carcinoma Who Failed to Systemic Therapy | unknown | Phase 2 | 49 | Hui-Chuan SunOTHER | 1 | Aug 13, 2021 | clinicaltrials |
| NCT04890392 | Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC | unknown | Phase 2 | 20 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Aug 12, 2021 | clinicaltrials |
| NCT05000554 | The Safety and Efficacy of PD-1 Monoantrapical Chemotherapy in the Treatment of Local Advanced Stomach Cancer | unknown | Phase 2 | 30 | The First Hospital of Jilin UniversityOTHER | 1 | Aug 11, 2021 | clinicaltrials |
| NCT04979663 | GEMOX Combined With Donafenib and Tislelizumab in Biliary Tract Cancer | unknown | Phase 1 / Phase 2 | 10 | Fudan UniversityOTHER | 1 | Aug 9, 2021 | clinicaltrials |
| NCT04996446 | ALPPS Combined With Tislelizumab in Liver Malignancy | unknown | Phase 2 | 20 | Fudan UniversityOTHER | 1 | Aug 9, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04988191 | Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Peking UniversityOTHER | 1 | Aug 3, 2021 | clinicaltrials |
| NCT03528785 | A Study of Nal-IRI With 5-FU, Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer(nITRo) | unknown | Phase 2 | 67 | Centro Ricerche Cliniche di VeronaOTHER | 1 | Aug 2, 2021 | clinicaltrials |
| NCT04984018 | Chidamide Plus Camrelizumab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade | unknown | Phase 2 | 73 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jul 30, 2021 | clinicaltrials |
| NCT04973475 | Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer | unknown | Phase 2 | 180 | Fujian Medical UniversityOTHER | 1 | Jul 22, 2021 | clinicaltrials |
| NCT04969029 | Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT04380012 | A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer | unknown | Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 15, 2021 | clinicaltrials |
| NCT04961788 | Anti-PD1 Antibody Toripalimab Combined With Gemox as First-line Therapy in Late-stage Intrahepatic Cholangiocarcinoma | unknown | Phase 2 | 30 | Shanghai Zhongshan HospitalOTHER | 1 | Jul 14, 2021 | clinicaltrials |
| NCT04961918 | The Efficacy of Hepatic Arterial Infusion Chemotherapy (HAIC) Combine Lenvatinib and Durvalumab (HILL) in Advanced Hepatocellular Carcinoma (HCC) | unknown | Phase 2 | 36 | Sun Yat-sen UniversityOTHER | 1 | Jul 14, 2021 | clinicaltrials |
| NCT04880811 | Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification | unknown | Phase 2 | 43 | Peking UniversityOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT03766178 | Study of Anti-PD-1 Antibody SHR-1210 Plus Nimotuzumab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 45 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT03951597 | Combined Therapy Using Oxaliplatin and Gemcitabine Chemotherapy, Lenvatinib and PD1 Antibody (JS001) for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma | unknown | Phase 2 | 30 | Shanghai Zhongshan HospitalOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT04275986 | Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma | unknown | Phase 2 | 56 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 7, 2021 | clinicaltrials |
| NCT01676259 | A Phase 2 Study of siG12D LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer(PROTACT) | unknown | Phase 2 | 80 | Silenseed LtdINDUSTRY | 2 | Jul 2, 2021 | clinicaltrials |
| NCT04948125 | Camrelizumab Combined With Apatinib for Advanced Gastric or Esophagogastric Adenocarcinoma | unknown | Phase 2 | 20 | Henan Cancer HospitalOTHER_GOV | 1 | Jul 1, 2021 | clinicaltrials |
| NCT04806243 | Carelizumab Combined With Regorafenib in the Treatment of HCC(CARE-2020) | unknown | Phase 2 | 69 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jun 30, 2021 | clinicaltrials |
| NCT04934618 | A Phase II Study of Carelizumab Combined With Irinotecan and Apatinib of Second-line Treatment for Advanced Gastric Cancer | unknown | Phase 2 | 85 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04293419 | Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer(DUREC) | unknown | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
Data updated 24 days agoSource updated Sep 28, 2021source: clinicaltrials