Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02298946 | AMP-224, a PD-1 Inhibitor, With Stereotactic Body Radiation Therapy in Metastatic Colorectal Cancer | completed | Phase 1 | 17 | National Cancer Institute (NCI)NIH | 1 | Feb 22, 2019 | clinicaltrials |
| NCT01871311 | A Phase I Study of Nilontinib and Cetuximab in Patients With Solid Tumors | terminated | Phase 1 | 15 | Georgetown UniversityOTHER | 1 | Feb 8, 2019 | clinicaltrials |
| NCT02433626 |
| Study of COTI-2 as Monotherapy or Combination Therapy for the Treatment of Malignancies(COTI2-101) |
| unknown |
| Phase 1 |
| 51 |
| Critical Outcome Technologies Inc.INDUSTRY |
| 1 |
| Feb 1, 2019 |
| clinicaltrials |
| NCT02648386 | Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery | unknown | Phase 1 / Phase 2 | 34 | Chinese Academy of SciencesOTHER_GOV | 1 | Jan 25, 2019 | clinicaltrials |
| NCT02205398 | Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy | terminated | Phase 1 | 13 | Novartis PharmaceuticalsINDUSTRY | 7 | Jan 22, 2019 | clinicaltrials |
| NCT02726334 | A Phase I, Dose Escalation Study of BNC101 in Patients With Metastatic Colorectal Cancer. | terminated | Phase 1 | 22 | Bionomics LimitedINDUSTRY | 1 | Jan 16, 2019 | clinicaltrials |
| NCT03634501 | Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer（NK）Cells | unknown | Phase 1 / Phase 2 | 200 | Xuanwu Hospital, BeijingOTHER | 1 | Jan 11, 2019 | clinicaltrials |
| NCT01923337 | Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer | completed | Phase 1 | 17 | University of California, DavisOTHER | 1 | Jan 4, 2019 | clinicaltrials |
| NCT02655952 | Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patients | completed | Phase 1 | 17 | WntResearch ABINDUSTRY | 2 | Dec 28, 2018 | clinicaltrials |
| NCT02860780 | A Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic Cancer | completed | Phase 1 | 9 | Eli Lilly and CompanyINDUSTRY | 2 | Dec 14, 2018 | clinicaltrials |
| NCT01282502 | Midostaurin (PKC412) for Locally Advanced Rectal Cancer | completed | Phase 1 | 19 | Massachusetts General HospitalOTHER | 1 | Dec 12, 2018 | clinicaltrials |
| NCT01560377 | Perfusion Assessment in Laparoscopic Left Anterior Resection(PILLAR II) | completed | Phase 1 | 147 | Novadaq Technologies ULC, now a part of StrykerINDUSTRY | 1 | Dec 11, 2018 | clinicaltrials |
| NCT00923520 | A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies | completed | Phase 1 | 60 | National Cancer Institute (NCI)NIH | 1 | Dec 5, 2018 | clinicaltrials |
| NCT02960594 | hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse(TRT-001) | completed | Phase 1 | 93 | Inovio PharmaceuticalsINDUSTRY | 1 | Nov 19, 2018 | clinicaltrials |
| NCT02391727 | Safety, Immunogenicity and Pharmacokinetics of SYN004 in Patients With Solid Tumors(SYN004_Ph_1) | completed | Phase 1 | 10 | Synermore Biologics Co., Ltd.INDUSTRY | 1 | Nov 16, 2018 | clinicaltrials |
| NCT00005030 | SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver | withdrawn | Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Nov 14, 2018 | clinicaltrials |
| NCT00685568 | Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis | completed | Phase 1 | 22 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 7, 2018 | clinicaltrials |
| NCT01661972 | Phase I/II Study of Capecitabine Plus Aflibercept to Treat Metastatic Colorectal Cancer(X-TRAP) | completed | Phase 1 / Phase 2 | 63 | John Strickler, M.D.OTHER | 1 | Oct 29, 2018 | clinicaltrials |
| NCT02718430 | VXM01 Phase I Study in Patients With Metastatic Colorectal Cancer With Liver Metastasis | completed | Phase 1 | 6 | Vaximm GmbHINDUSTRY | 1 | Oct 19, 2018 | clinicaltrials |
| NCT01117428 | Sym004 in Patients With Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 111 | Symphogen A/SINDUSTRY | 3 | Oct 15, 2018 | clinicaltrials |
| NCT03356158 | A Study of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Metastatic Colorectal Cancer | unknown | Phase 1 | 21 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Sep 17, 2018 | clinicaltrials |
| NCT02191761 | Safety and Pharmacokinetics of SM04755 in Subjects With Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer | completed | Phase 1 | 13 | Biosplice Therapeutics, Inc.INDUSTRY | 1 | Sep 7, 2018 | clinicaltrials |
| NCT02650635 | TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors | terminated | Phase 1 | 4 | Mayo ClinicOTHER | 1 | Sep 5, 2018 | clinicaltrials |
| NCT03182894 | Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | James J LeeOTHER | 1 | Aug 28, 2018 | clinicaltrials |
| NCT02611661 | Local Ablative Strategies After Endovascular Radioembolization(LASER) | terminated | Phase 1 | 9 | Washington University School of MedicineOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT00925015 | Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016) | completed | Phase 1 | 20 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Aug 15, 2018 | clinicaltrials |
| NCT00458809 | Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer | completed | Phase 1 | 16 | Wake Forest University Health SciencesOTHER | 1 | Aug 9, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03601598 | A Trial of SHR-1210 in Combination With SHR6390 in Patients With Advanced CRC, NSCLC and HCC | unknown | Phase 1 / Phase 2 | 41 | Harbin Medical UniversityOTHER | 0 | Jul 26, 2018 | clinicaltrials |
| NCT02062749 | Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | completed | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 19, 2018 | clinicaltrials |
| NCT01705002 | Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors. | completed | Phase 1 | 88 | Lipomedix Pharmaceuticals Inc.INDUSTRY | 1 | Jul 10, 2018 | clinicaltrials |
| NCT02835833 | Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors | completed | Phase 1 | 21 | University of Alabama at BirminghamOTHER | 1 | Jul 10, 2018 | clinicaltrials |
| NCT01197664 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery | terminated | Phase 1 | 2 | Wake Forest University Health SciencesOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT02423954 | Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)(NivoPlus) | terminated | Phase 1 / Phase 2 | 33 | Western Regional Medical CenterOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT01048580 | Study of Perifosine + Capecitabine for Colon Cancer Patients | completed | Phase 1 | 10 | AEterna ZentarisINDUSTRY | 0 | Jun 28, 2018 | clinicaltrials |
| NCT03542799 | EGFR-IL12-CART Cells for Patients With Metastatic Colorectal Cancer(EGFRCART) | unknown | Phase 1 | 20 | Shenzhen Second People's HospitalOTHER | 1 | May 31, 2018 | clinicaltrials |
| NCT00827580 | Eniluracil Hand Foot Syndrome | terminated | Phase 1 | 3 | West Virginia UniversityOTHER | 1 | May 30, 2018 | clinicaltrials |
| NCT00003344 | Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer | completed | Phase 1 / Phase 2 | 49 | Medical University of South CarolinaOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT03253185 | A Study of SC-007 in Subjects With Advanced Cancer | terminated | Phase 1 | 7 | AbbVieINDUSTRY | 1 | Apr 27, 2018 | clinicaltrials |
| NCT00149396 | Safety & Efficacy of NV1020 in Colorectal Cancer Metastatic to the Liver | completed | Phase 1 / Phase 2 | 32 | MediGeneINDUSTRY | 1 | Apr 24, 2018 | clinicaltrials |
| NCT01975454 | Study of TLBZT Based Herbal Therapy Plus Chemotherapy for Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 62 | Shanghai University of Traditional Chinese MedicineOTHER | 1 | Apr 19, 2018 | clinicaltrials |
| NCT02577588 | Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer(ATACC) | terminated | Phase 1 | 1 | National Center for Tumor Diseases, HeidelbergOTHER | 1 | Apr 11, 2018 | clinicaltrials |
| NCT01520389 | Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment | completed | Phase 1 | 112 | Merrimack PharmaceuticalsINDUSTRY | 1 | Mar 21, 2018 | clinicaltrials |
| NCT03307603 | Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 0 | Feb 27, 2018 | clinicaltrials |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver | terminated | Phase 1 | 2 | Fox Chase Cancer CenterOTHER | 1 | Feb 26, 2018 | clinicaltrials |
| NCT03435666 | A Bioequivalence Study of Capecitabine Tablets 500 mg in Adult Cancer Patients Under Fed Condition(Capecitabine) | unknown | Phase 1 | 45 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Feb 19, 2018 | clinicaltrials |
| NCT01460134 | A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers | completed | Phase 1 | 90 | Celldex TherapeuticsINDUSTRY | 1 | Jan 31, 2018 | clinicaltrials |
| NCT01843725 | Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers(MOMENTUM1) | completed | Phase 1 | 37 | Jules Bordet InstituteOTHER | 1 | Jan 31, 2018 | clinicaltrials |
| NCT02041481 | MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Jan 25, 2018 | clinicaltrials |
Data updated 24 days agoSource updated Feb 22, 2019source: clinicaltrials