Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05174286 | Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk(CHURCH) | recruiting | N/A | 880 | Columbia UniversityOTHER | 1 | Sep 16, 2025 | clinicaltrials |
| NCT07168876 | Colon Cancer Liquid Biopsy Investigation of Methylation-based Biomarkers Evaluation Using Delta-HLD (CLIMBED)(CLIMBED) | recruiting | — | 3,200 | Epiliquid Holding, IncINDUSTRY | 1 |
| Sep 11, 2025 |
| clinicaltrials |
| NCT05107674 | A Study of NX-1607 in Adults With Advanced Malignancies | recruiting | Phase 1 | 345 | Nurix Therapeutics, Inc.INDUSTRY | 2 | Sep 9, 2025 | clinicaltrials |
| NCT06682793 | A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression(DENALI-1) | recruiting | Phase 1 / Phase 2 | 240 | A2 Biotherapeutics Inc.INDUSTRY | 1 | Sep 9, 2025 | clinicaltrials |
| NCT06780423 | Structural Characteristics of Trunk and Limb Muscles in Cachectic Colorectal Cancer Patients(CTLm-CCP) | recruiting | — | 60 | Hasselt UniversityOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT06783569 | A First-in-Human Escalation and Expansion Study of Patients With Advanced Solid Tumors | recruiting | Phase 1 | 94 | JiaRay GroupINDUSTRY | 1 | Sep 9, 2025 | clinicaltrials |
| NCT05938322 | Ketogenic Diet Compliance in Patients Undergoing Radiotherapy for Pelvic Cancers(KOMPARC) | recruiting | N/A | 194 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT05713903 | Laparoscopic Versus Open Right Colectomy for Right Colon Cancer | recruiting | N/A | 114 | Larissa University HospitalOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT06770270 | Pucotenlimab Plus Radiotherapy and Chemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cance(PUCRT)(PUCRT) | recruiting | Phase 2 | 68 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT07154316 | Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer | recruiting | Phase 2 | 138 | Fudan UniversityOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT05706779 | Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer(NEORAF) | recruiting | Phase 2 | 30 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT05950503 | Role of MRI in the Evaluation of Hepatic Metastases of Colorectal Cancer(RMN-CRC) | recruiting | — | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06202131 | Use of Ctdna in Patients With Gastrointestinal Tract Tumors(ctdna-GI) | recruiting | — | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT07150949 | Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC) | recruiting | Phase 2 | 138 | Fudan UniversityOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06490536 | The Sagittarius Trial | recruiting | Phase 3 | 700 | IFOM ETS - The AIRC Institute of Molecular OncologyOTHER | 3 | Aug 29, 2025 | clinicaltrials |
| NCT06911970 | Impact of Aerobic Exercise on the Anticancer Immune Response in Patients Receiving Cancer Treatment(Immuno-Ex) | recruiting | N/A | 44 | Université de SherbrookeOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT07046468 | Smart Pill for Measuring Gut Health in Colon Inflammation and Colon Cancer(SPIRIT) | recruiting | — | 10 | Radboud University Medical CenterOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT05576480 | SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer(SPARC) | recruiting | Phase 2 | 55 | Ruijin HospitalOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT06887218 | 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer | recruiting | Phase 2 | 57 | The Methodist Hospital Research InstituteOTHER | 1 | Aug 27, 2025 | clinicaltrials |
| NCT04120935 | ALFAOMEGA Master Observational Trial(ALFAOMEGA) | recruiting | — | 3,000 | IFOM ETS - The AIRC Institute of Molecular OncologyOTHER | 2 | Aug 24, 2025 | clinicaltrials |
| NCT05101382 | A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)(ALFAOMEGA-R) | recruiting | — | 500 | IFOM ETS - The AIRC Institute of Molecular OncologyOTHER | 2 | Aug 24, 2025 | clinicaltrials |
| NCT06867822 | Trial of ProAgio in Advanced/Metastatic Colorectal Cancer | recruiting | Phase 1 | 27 | University of Alabama at BirminghamOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT06508307 | A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors | recruiting | Phase 1 | 21 | GONGCHU Biotechnology Co., LtdOTHER | 1 | Aug 21, 2025 | clinicaltrials |
| NCT07129512 | Ultrasonic Versus Conventional Clipping Hemostasis in Laparoscopic Colorectal Surgery | recruiting | N/A | 304 | Yonsei UniversityOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT04429542 | Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors | recruiting | Phase 1 | 292 | Bicara TherapeuticsINDUSTRY | 3 | Aug 15, 2025 | clinicaltrials |
| NCT06366841 | Stigma and Psychological profilE in REctal-anal caNcer pAtients(SERENA) | recruiting | — | 148 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06645236 | DHF-20-1839-2: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit | recruiting | N/A | 600 | QIAGEN Gaithersburg, IncINDUSTRY | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06298916 | 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer(PHANTOM) | recruiting | Phase 1 / Phase 2 | 26 | Lantheus Medical ImagingINDUSTRY | 1 | Aug 12, 2025 | clinicaltrials |
| NCT06864338 | Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test(eAArly DETECT) | recruiting | — | 2,700 | Mainz BiomedINDUSTRY | 1 | Aug 12, 2025 | clinicaltrials |
| NCT07114627 | Impact of CES1 Genotype on Capecitabine Exposure in Cancer Patients(ESCAPE) | recruiting | — | 66 | Erasmus Medical CenterOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT05732389 | Immunotherapy in Patients With Early dMMR Rectal Cancer(RESET-R) | recruiting | Phase 2 | 39 | Odense University HospitalOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT06958419 | Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC) | recruiting | Phase 2 / Phase 3 | 286 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT07108348 | ADAR1 Expression Level in Rectal Cancer(ADAR1TNT) | recruiting | — | 50 | Necmettin Erbakan UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT07108517 | A Manualized Post-Traumatic Growth Intervention for People With Cancer in Greece - IC-Growth(IC-Growth) | recruiting | N/A | 180 | Centre for Research and Technology HellasOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT06856187 | Second-line Standard Treatment Sequential TAS-102 and Bevacizumab Combined With Local Treatment in Advanced Colorectal Cancer(TASBEL) | recruiting | Phase 2 | 119 | Fudan UniversityOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07108127 | Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal Cancer(NePHera) | recruiting | Phase 2 | 24 | Peking Union Medical College HospitalOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT05592886 | A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers | recruiting | N/A | 649 | Chinese University of Hong KongOTHER | 2 | Aug 1, 2025 | clinicaltrials |
| NCT06462963 | OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)(SPRINT) | recruiting | N/A | 302 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 4 | Aug 1, 2025 | clinicaltrials |
| NCT06200831 | Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases(SYLMET) | recruiting | N/A | 80 | Oslo University HospitalOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06917963 | Study of Treatment With Intensified Omeprazole Treatment to Prevent High Output Stoma 1(STOP-HOS-1) | recruiting | N/A | 80 | Medical University of GdanskOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT07095439 | Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients | recruiting | Phase 2 | 38 | Ain Shams UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06441565 | Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer | recruiting | Phase 2 / Phase 3 | 84 | Sun Yat-sen UniversityOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT04927897 | DETECT: Target Volume for Rectal Endoluminal Radiation Boosting(DETECT) | recruiting | — | 50 | Maastricht Radiation OncologyOTHER | 1 | Jul 28, 2025 | clinicaltrials |
| NCT07087561 | Short-Term Nutritional Enhancement Combined With Health Education in Postoperative Colorectal Cancer Patients: A Randomized Controlled Trial(NUTRI-CRC) | recruiting | N/A | 360 | Xiaoqin LuoOTHER | 1 | Jul 28, 2025 | clinicaltrials |
| NCT06846268 | Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer | recruiting | Phase 2 | 20 | National University Hospital, SingaporeOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT06940388 | Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.(TOTAL) | recruiting | Phase 2 | 134 | brenner baruchOTHER | 2 | Jul 24, 2025 | clinicaltrials |
| NCT05571644 | Neoadjuvant Treatment With mFOLFOXIRI Plus Cadonilimab (AK104) Versus mFOLFOX6 in Locally Advanced Colorectal Cancer(OPTICAL-2) | recruiting | Phase 2 | 143 | Sun Yat-sen UniversityOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT05787197 | ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases(CLIMES) | recruiting | — | 232 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 23, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Sep 16, 2025source: clinicaltrials