Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (419)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02254954 | Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma | terminated | Phase 1 | 30 | ActelionINDUSTRY | 1 | Feb 27, 2018 | clinicaltrials |
| NCT00623077 | MT2004-30: Tomotherapy for Solid Tumors | terminated | Phase 1 | 23 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 5, 2017 | clinicaltrials |
| NCT00003926 |
| Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors |
| terminated |
| Phase 1 |
| 13 |
| Masonic Cancer Center, University of MinnesotaOTHER |
| 1 |
| Nov 29, 2017 |
| clinicaltrials |
| NCT01339039 | Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma | terminated | Phase 1 | 26 | Patrick Y. Wen, MDOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT02510950 | Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma | terminated | Phase 1 | 1 | Washington University School of MedicineOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT01666600 | NOA-12: BIBF1120 and R-RT in Glioblastoma | terminated | Phase 1 / Phase 2 | 63 | Prof. Dr. Wolfgang WickOTHER | 1 | Nov 1, 2017 | clinicaltrials |
| NCT01526837 | Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence | terminated | Phase 1 | 1 | Brain & Spine Surgeons of New YorkOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT02648633 | Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma | terminated | Phase 1 | 4 | University of VirginiaOTHER | 1 | May 31, 2017 | clinicaltrials |
| NCT01902771 | Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors | terminated | Phase 1 | 1 | Edward ZigaOTHER | 1 | Mar 10, 2017 | clinicaltrials |
| NCT00456612 | Radiosurgery for Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 4 | Beth Israel Deaconess Medical CenterOTHER | 1 | Mar 6, 2017 | clinicaltrials |
| NCT01148966 | Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors | terminated | Phase 1 | 6 | University of WashingtonOTHER | 1 | Feb 15, 2017 | clinicaltrials |
| NCT02025231 | Image Guided Reirradiation of High-grade Glioma | terminated | Phase 1 / Phase 2 | 31 | Rigshospitalet, DenmarkOTHER | 2 | Feb 8, 2017 | clinicaltrials |
| NCT02371031 | FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas | terminated | Phase 1 | 11 | Washington University School of MedicineOTHER | 1 | Nov 30, 2016 | clinicaltrials |
| NCT02370563 | PET Imaging of Intracranial Cancers With 18F-FSPG | terminated | Phase 1 | 26 | Lantheus Biosciences Ltd.INDUSTRY | 1 | Sep 2, 2016 | clinicaltrials |
| NCT01989052 | Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma | terminated | Phase 1 | 9 | Annick DesjardinsOTHER | 1 | Aug 4, 2016 | clinicaltrials |
| NCT02031965 | Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery | terminated | Phase 1 | 2 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | May 30, 2016 | clinicaltrials |
| NCT01499251 | Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma | terminated | Phase 1 | 75 | ActelionINDUSTRY | 1 | May 5, 2016 | clinicaltrials |
| NCT01954030 | Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure | terminated | Phase 1 | 17 | Annick DesjardinsOTHER | 1 | Feb 19, 2016 | clinicaltrials |
| NCT01189240 | RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma | terminated | Phase 1 / Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Dec 14, 2015 | clinicaltrials |
| NCT01122888 | Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme | terminated | Phase 1 | 41 | National Cancer Institute (NCI)NIH | 1 | Apr 28, 2015 | clinicaltrials |
| NCT01378481 | High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT01088763 | Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia | terminated | Phase 1 | 129 | National Cancer Institute (NCI)NIH | 2 | Nov 5, 2014 | clinicaltrials |
| NCT01403285 | Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma | terminated | Phase 1 | 6 | Immatics Biotechnologies GmbHINDUSTRY | 1 | May 19, 2014 | clinicaltrials |
| NCT01205334 | Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme(COGLI) | terminated | Phase 1 / Phase 2 | 2 | Baylor College of MedicineOTHER | 1 | Aug 26, 2013 | clinicaltrials |
| NCT00650949 | Efficacy Study of CYT997 in Combination With Carboplatin in Glioblastoma | terminated | Phase 1 / Phase 2 | 20 | Gilead SciencesINDUSTRY | 1 | May 3, 2013 | clinicaltrials |
| NCT00959946 | Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer | terminated | Phase 1 / Phase 2 | 32 | PfizerINDUSTRY | 6 | Feb 22, 2013 | clinicaltrials |
| NCT01269411 | RO4929097 in Treating Patients With Recurrent Invasive Gliomas | terminated | Phase 1 | 22 | National Cancer Institute (NCI)NIH | 1 | Feb 7, 2013 | clinicaltrials |
| NCT00005856 | Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 59 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00006773 | Bortezomib in Treating Patients With Recurrent Glioma | terminated | Phase 1 | 42 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00036855 | Radiolabeled Monoclonal Antibody With or Without Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Lymphoma | terminated | Phase 1 | 36 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2013 | clinicaltrials |
| NCT00110032 | Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors | terminated | Phase 1 | 46 | National Cancer Institute (NCI)NIH | 1 | Jan 16, 2013 | clinicaltrials |
| NCT00948389 | Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM) | terminated | Phase 1 / Phase 2 | 28 | Bristol-Myers SquibbINDUSTRY | 4 | Aug 31, 2012 | clinicaltrials |
| NCT00272870 | Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy | terminated | Phase 1 | 1 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Aug 29, 2012 | clinicaltrials |
| NCT00508456 | Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM | terminated | Phase 1 | 18 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 16, 2012 | clinicaltrials |
| NCT00376103 | Radiation Boost for Newly Diagnosed Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 3 | Methodist Healthcare - MemphisOTHER | 1 | Sep 18, 2009 | clinicaltrials |
| NCT00115453 | Boron Neutron Capture Therapy (BNCT) as Treatment of Glioblastoma | terminated | Phase 1 / Phase 2 | 50 | Boneca CorporationINDUSTRY | 1 | Aug 18, 2008 | clinicaltrials |
Data updated 22 days agoSource updated Feb 27, 2018source: clinicaltrials