Subtype
Malignant Anorectal Neoplasm
CI-CAN-00005864Explore in graph →
452 active trials1 approved drugs6 evidence items
- NCIt
- C215225
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Subtype
CI-CAN-00005864Explore in graph →
Clinical trials
1,783 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (174)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06914245 | Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable)(Treatable) | recruiting | N/A | 150 | KU LeuvenOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07359989 | Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer | recruiting | N/A | 33 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jan 22, 2026 |
| clinicaltrials |
| NCT07339904 | ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment Regimens(ProLARS) | recruiting | N/A | 100 | University Hospital, AntwerpOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT06715839 | Target-specific immunoPET Imaging of Digestive System Carcinoma | recruiting | N/A | 400 | RenJi HospitalOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT06380101 | Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)(NEAAR-LARC) | recruiting | N/A | 30 | University of South FloridaOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT06236633 | Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum(AMIREMBOL_2) | recruiting | N/A | 30 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT06522256 | Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial(HPVsign) | recruiting | N/A | 100 | ANRS, Emerging Infectious DiseasesOTHER_GOV | 1 | Dec 4, 2025 | clinicaltrials |
| NCT06565052 | The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial | recruiting | N/A | 40 | Dana-Farber Cancer InstituteOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT03958240 | Deciphering Mechanisms Underlying Cancer Immunogenicity(DECIDE) | recruiting | N/A | 1,100 | Institut Claudius RegaudOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT05938322 | Ketogenic Diet Compliance in Patients Undergoing Radiotherapy for Pelvic Cancers(KOMPARC) | recruiting | N/A | 194 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT06328361 | Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer(NORPPA-1) | recruiting | N/A | 200 | Tampere University HospitalOTHER | 2 | Sep 2, 2025 | clinicaltrials |
| NCT06209099 | Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer | recruiting | N/A | 96 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 12, 2025 | clinicaltrials |
| NCT06761287 | Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer(OPAL) | recruiting | N/A | 20 | Centre Hospitalier Universitaire Saint PierreOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT06214988 | Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer(SELSA) | recruiting | N/A | 212 | Skane University HospitalOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT05914766 | An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer(PATHWAYS) | recruiting | N/A | 80 | Massachusetts General HospitalOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT03061435 | Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.(Vulvar-AIN) | recruiting | N/A | 110 | Dr. Danielle VicusOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT06740357 | Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients(EVAREC) | recruiting | N/A | 270 | Centre Hospitalier Universitaire DijonOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT06630793 | IMRT Versus IMPT With Concurrent Chemotherapy for Locally Advanced Anal Canal Cancer(IMPAC) | recruiting | N/A | 108 | Tata Memorial CentreOTHER | 1 | Apr 8, 2025 | clinicaltrials |
| NCT06894797 | Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer. | recruiting | N/A | 68 | Peking University Cancer Hospital & InstituteOTHER | 1 | Mar 25, 2025 | clinicaltrials |
| NCT06854679 | Dose Escalated Radiotherapy for Rectal Cancers Using MR-guided Radiotherapy(ANDROMEDA) | recruiting | N/A | 13 | Royal Marsden NHS Foundation TrustOTHER | 1 | Mar 3, 2025 | clinicaltrials |
| NCT06831981 | Hyperthermia With Chemoradiotherapy in Rectal Cancer(ARO 2024-13) | recruiting | N/A | 264 | University Hospital TuebingenOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT04103567 | Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Treatment in Rectal Cancers(MICARE) | recruiting | N/A | 220 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT06805045 | Image-Guided Surgery In The Treatment Of Rectal Cancer (AR_CRC) | recruiting | N/A | 50 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Feb 3, 2025 | clinicaltrials |
| NCT06792604 | Host Genome Methylation: a Screening Tool in Anal Cancer Detection(AMethysT) | recruiting | N/A | 770 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT05000697 | Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait(CCHOWW) | recruiting | N/A | 216 | Hospital Alemão Oswaldo CruzOTHER | 3 | Nov 27, 2024 | clinicaltrials |
| NCT04999007 | Artificial Intelligence Assists Surgeons' Decision Making | recruiting | N/A | 616 | Jichao QinOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT04103372 | Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery(PRESERVE) | recruiting | N/A | 200 | Imperial College LondonOTHER | 1 | Nov 4, 2024 | clinicaltrials |
| NCT05424692 | Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer | recruiting | N/A | 200 | Peking Union Medical College HospitalOTHER | 1 | Nov 4, 2024 | clinicaltrials |
| NCT06653452 | Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer | recruiting | N/A | 30 | Peking Union Medical College HospitalOTHER | 1 | Oct 22, 2024 | clinicaltrials |
| NCT02704520 | Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial(TRIGGER) | recruiting | N/A | 441 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT03303547 | Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits(COMET) | recruiting | N/A | 200 | Imperial College LondonOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT06633133 | Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision | recruiting | N/A | 620 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT05964530 | Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission | recruiting | N/A | 180 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT05215535 | Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial.(Limerick) | recruiting | N/A | 400 | Vastra Gotaland RegionOTHER_GOV | 1 | Aug 19, 2024 | clinicaltrials |
| NCT05572801 | NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer | recruiting | N/A | 400 | Aarhus University HospitalOTHER | 4 | Aug 14, 2024 | clinicaltrials |
| NCT06536127 | Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer(IMMUNOREC) | recruiting | N/A | 100 | Institut Sainte CatherineOTHER | 1 | Aug 2, 2024 | clinicaltrials |
| NCT03465982 | Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer(TiMiSNAR) | recruiting | N/A | 340 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT05883800 | Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer(TNT-RECORD) | recruiting | N/A | 61 | Haukeland University HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06222255 | The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)(TraLARS) | recruiting | N/A | 52 | Seoul National University HospitalOTHER | 1 | Jan 24, 2024 | clinicaltrials |
| NCT02649647 | Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy(PERN) | recruiting | N/A | 240 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 6, 2023 | clinicaltrials |
| NCT06043999 | Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | recruiting | N/A | 392 | Sun Yat-sen UniversityOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT05316103 | Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy | recruiting | N/A | 68 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | May 12, 2023 | clinicaltrials |
| NCT05772923 | Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision(OPAXX) | recruiting | N/A | 168 | The Netherlands Cancer InstituteOTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT04743102 | Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer(BIOPSY) | recruiting | N/A | 260 | Beijing Chao Yang HospitalOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT04527861 | Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer(CSILS) | recruiting | N/A | 710 | Ruijin HospitalOTHER | 1 | Oct 10, 2022 | clinicaltrials |
| NCT05049317 | Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision | recruiting | N/A | 88 | Renmin Hospital of Wuhan UniversityOTHER | 1 | Nov 1, 2021 | clinicaltrials |
| NCT04172753 | Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac | recruiting | N/A | 472 | University Hospital TuebingenOTHER | 1 | Nov 21, 2019 | clinicaltrials |
| NCT03064646 | Organ Preservation in Locally Advanced Rectal Cancer(PRONAR) | recruiting | N/A | 30 | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat ValencianaOTHER | 1 | Sep 27, 2018 | clinicaltrials |
Data updated 23 days agoSource updated Jan 23, 2026source: clinicaltrials