Cancer Family
Lung Neoplasm
CI-CAN-00000221Explore in graph →
Non-malignant2,724 active trials51 approved drugs619 evidence items
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Cancer Family
CI-CAN-00000221Explore in graph →
Genomics
41 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
163 cases with simple somatic mutation data · 163 cases total · 2026-01-07 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 64 |
| 163 |
| 39.3% |
| cbioportal |
| 2 | KRAS | Ssm | 60 | 163 | 36.8% | cbioportal |
| 3 | STK11 | Ssm | 34 | 163 | 20.9% | cbioportal |
| 4 | EGFR | Ssm | 30 | 163 | 18.4% | cbioportal |
| 5 | LRP1B | Ssm | 16 | 163 | 9.8% | cbioportal |
| 7 | NF1 | Ssm | 13 | 163 | 8% | cbioportal |
| 6 | ATM | Ssm | 13 | 163 | 8% | cbioportal |
| 8 | APC | Ssm | 11 | 163 | 6.7% | cbioportal |
| 9 | EPHA3 | Ssm | 10 | 163 | 6.1% | cbioportal |
| 10 | CDKN2A | Ssm | 9 | 163 | 5.5% | cbioportal |
| 11 | PTPRD | Ssm | 9 | 163 | 5.5% | cbioportal |
| 13 | KDR | Ssm | 8 | 163 | 4.9% | cbioportal |
| 12 | ERBB4 | Ssm | 8 | 163 | 4.9% | cbioportal |
| 17 | NTRK1 | Ssm | 7 | 163 | 4.3% | cbioportal |
| 16 | MYO3B | Ssm | 7 | 163 | 4.3% | cbioportal |
| 18 | NTRK3 | Ssm | 7 | 163 | 4.3% | cbioportal |
| 20 | RB1 | Ssm | 7 | 163 | 4.3% | cbioportal |
| 19 | PRKDC | Ssm | 7 | 163 | 4.3% | cbioportal |
| 15 | FGFR4 | Ssm | 7 | 163 | 4.3% | cbioportal |
| 14 | EPHA5 | Ssm | 7 | 163 | 4.3% | cbioportal |
| 21 | EPHA7 | Ssm | 6 | 163 | 3.7% | cbioportal |
| 23 | LTK | Ssm | 6 | 163 | 3.7% | cbioportal |
| 25 | PDGFRA | Ssm | 6 | 163 | 3.7% | cbioportal |
| 24 | NTRK2 | Ssm | 6 | 163 | 3.7% | cbioportal |
| 22 | INSRR | Ssm | 6 | 163 | 3.7% | cbioportal |
| 29 | INHBA | Ssm | 5 | 163 | 3.1% | cbioportal |
| 27 | DOCK3 | Ssm | 5 | 163 | 3.1% | cbioportal |
| 38 | ROBO2 | Ssm | 5 | 163 | 3.1% | cbioportal |
| 28 | EPHB6 | Ssm | 5 | 163 | 3.1% | cbioportal |
| 32 | MAP3K21 | Ssm | 5 | 163 | 3.1% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07