Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03300609 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | terminated | Phase 3 | 4 | University of Southern CaliforniaOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT03480152 | Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jun 2, 2020 |
| NCT03258541 | Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy | terminated | N/A | 2 | Thomas ZilliOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT02052921 | Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy | terminated | N/A | 13 | Instituto do Cancer do Estado de São PauloOTHER | 1 | May 11, 2020 | clinicaltrials |
| NCT01609231 | A Trial of Dalotuzumab in Combination With Irinotecan Versus Cetuximab and Irinotecan for Participants With Metastatic Rectal Cancers (mRC) (MK-0646-025) | terminated | Phase 2 | 11 | Merck Sharp & Dohme LLCINDUSTRY | 0 | May 4, 2020 | clinicaltrials |
| NCT00602329 | MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer | terminated | Phase 2 | 5 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 28, 2020 | clinicaltrials |
| NCT02324556 | A LAparoscopic and TransAnal Total Mesorectal Excision (TME) for Rectal Cancer Trial(LATA) | terminated | — | 6 | Sahlgrenska University HospitalOTHER | 1 | Apr 28, 2020 | clinicaltrials |
| NCT03705013 | Observational Study of Sub-populations From Cologuard Post-Approval Study (2014-01) | terminated | — | 51 | Exact Sciences CorporationINDUSTRY | 1 | Apr 14, 2020 | clinicaltrials |
| NCT03487484 | Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With or Without Stoma | terminated | — | 5 | University Hospital, Basel, SwitzerlandOTHER | 1 | Apr 10, 2020 | clinicaltrials |
| NCT00353457 | Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma | terminated | Phase 2 | 6 | Abramson Cancer Center at Penn MedicineOTHER | 0 | Apr 9, 2020 | clinicaltrials |
| NCT00091286 | Vaccine Therapy in Treating Patients With Stage IIB, Stage III, or Stage IV Colorectal Cancer | terminated | Early Phase 1 | 11 | Craig L Slingluff, JrOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02889276 | Effects of Functional Exercise on Fitness and QoL in Cancer Survivors(RETRACE) | terminated | N/A | 4 | University of PortsmouthOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma(UFT RT Phase 3) | terminated | Phase 3 | 219 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT01317433 | Pre-emptive Cycline Treatment on Cetuximab Induced Skin Toxicity in Colorectal Cancer(SKINUX) | terminated | N/A | 25 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT01547923 | Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines(DPD côlon) | terminated | N/A | 1,142 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT02141295 | A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal Cancer(McCAVE) | terminated | Phase 2 | 197 | Hoffmann-La RocheINDUSTRY | 7 | Mar 25, 2020 | clinicaltrials |
| NCT02797405 | Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay(THEODORA) | terminated | N/A | 97 | Centre Leon BerardOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT01504477 | Panitumumab and Bortezomib for Patients With Advanced Colorectal Cancer | terminated | Phase 1 / Phase 2 | 6 | Georgetown UniversityOTHER | 1 | Mar 16, 2020 | clinicaltrials |
| NCT01557881 | Positron Emission Tomography/Magnetic Resonance Imaging in Patients | terminated | N/A | 98 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 24, 2020 | clinicaltrials |
| NCT00544700 | Bevacizumab in Treating Patients Who Have Undergone First-Line Therapy for Metastatic Colorectal Cancer | terminated | Phase 3 | 265 | Swiss Cancer InstituteOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT03035279 | A Study of SC-006 and in Combination With ABBV-181 in Subjects With Advanced Colorectal Cancer | terminated | Phase 1 | 29 | AbbVieINDUSTRY | 1 | Feb 20, 2020 | clinicaltrials |
| NCT02687009 | A Study of Niclosamide in Patients With Resectable Colon Cancer | terminated | Phase 1 | 1 | Michael Morse, MDOTHER | 1 | Feb 19, 2020 | clinicaltrials |
| NCT01057017 | First-Line FOLFOX-Bevacizumab for Advanced Colorectal Cancer With Wild-Type Ras | terminated | Phase 2 | 5 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT01669720 | Adjuvant Aflibercept for Metastatic Colorectal Cancer(C261) | terminated | Phase 2 | 10 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT01671488 | A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer(276) | terminated | Phase 1 / Phase 2 | 11 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT00955240 | Radiation Therapy, Cisplatin, Fluorouracil, and Cetuximab in Treating Patients With Locally Advanced Anal Cancer | terminated | Phase 2 | 16 | UNICANCEROTHER | 1 | Feb 11, 2020 | clinicaltrials |
| NCT02425683 | Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX | terminated | Phase 2 | 24 | US Oncology ResearchINDUSTRY | 1 | Feb 10, 2020 | clinicaltrials |
| NCT02576665 | A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6) | terminated | Phase 1 | 21 | Tocagen Inc.INDUSTRY | 1 | Feb 7, 2020 | clinicaltrials |
| NCT02809846 | Quell Opioid Reduction and Pain Relief in Patients With Cancer | terminated | N/A | 33 | Scripps Translational Science InstituteOTHER | 1 | Jan 21, 2020 | clinicaltrials |
| NCT01993472 | Study of Andrographolides With or Without Capecitabine to Treat Colorectal Cancer(AGCRC-013) | terminated | Phase 2 | 308 | Gu YanhongOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT00394602 | Chemoradiation-Induced Nausea and Emesis: Quality of Life | terminated | — | 207 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 2, 2020 | clinicaltrials |
| NCT02014116 | A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body | terminated | Phase 1 | 51 | Eli Lilly and CompanyINDUSTRY | 4 | Dec 27, 2019 | clinicaltrials |
| NCT01532804 | 2nd-line Treatment of Metastatic Colorectal Cancer(BEVATOMOX) | terminated | Phase 2 | 83 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Dec 26, 2019 | clinicaltrials |
| NCT01336985 | Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads | terminated | Phase 1 | 5 | National Institutes of Health Clinical Center (CC)NIH | 1 | Dec 17, 2019 | clinicaltrials |
| NCT02328664 | SCar-biopsies After Malignant Colorectal Polypectomy of Uncertain RAdicality(SCAPURA) | terminated | N/A | 246 | Dr. Frank ter Borg MD PhDOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT00923052 | The Natural History of Solid Organ Cancer Stem Cells (SOCSC) | terminated | — | 190 | National Cancer Institute (NCI)NIH | 1 | Dec 16, 2019 | clinicaltrials |
| NCT00580073 | Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum | terminated | Phase 2 | 6 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT01902823 | Effect of Cancer Nurse Navigators on Patient Outcomes | terminated | Phase 2 / Phase 3 | 16 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT01881932 | Acupuncture to Prevent Chemotherapy Dose Reduction Due to Chemotherapy-induced Peripheral Neuropathy in Breast and Colorectal Cancer Patients (GCC1232) | terminated | N/A | 19 | University of Maryland, BaltimoreOTHER | 1 | Nov 7, 2019 | clinicaltrials |
| NCT02290574 | Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME: Prospective Phase II Trial(NEOTREAT) | terminated | N/A | 14 | Samsung Medical CenterOTHER | 1 | Nov 1, 2019 | clinicaltrials |
| NCT02318901 | Pembrolizumab and Monoclonal Antibody Therapy in Advanced Cancer(PembroMab) | terminated | Phase 1 / Phase 2 | 16 | Western Regional Medical CenterOTHER | 1 | Oct 21, 2019 | clinicaltrials |
| NCT02685046 | Imatinib as Pre-operative Anti-Colon Cancer Targeted Therapy(ImPACCT) | terminated | Phase 2 | 5 | UMC UtrechtOTHER | 1 | Oct 14, 2019 | clinicaltrials |
| NCT00078897 | Selenium for Prevention of Adenomatous Colorectal Polyps | terminated | Phase 3 | 1,621 | University of ArizonaOTHER | 1 | Sep 24, 2019 | clinicaltrials |
| NCT03682133 | PreColo Practice Variation | terminated | — | 20 | Radboud University Medical CenterOTHER | 1 | Sep 13, 2019 | clinicaltrials |
| NCT00397878 | AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer | terminated | Phase 2 | 10 | National Cancer Institute (NCI)NIH | 1 | Aug 20, 2019 | clinicaltrials |
| NCT02233595 | Evaluation of Rectal Cancer Treatment Response Using PET/MRI(Rectal PET/MRI) | terminated | — | 7 | University of California, San FranciscoOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03204201 | Validation of ICG to Identify the Urethra During Rectal Surgery | terminated | Phase 1 / Phase 2 | 5 | Oxford University Hospitals NHS TrustOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03204994 | Fluorescence Targeted Pelvic Lymph Node Mapping | terminated | Phase 1 / Phase 2 | 1 | Oxford University Hospitals NHS TrustOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03677960 | Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection | terminated | Phase 1 | 6 | Antiva BiosciencesINDUSTRY | 2 | Jul 24, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Jun 11, 2020source: clinicaltrials