Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
Loading cancer entity…
Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00655499 | Panitumumab and Irinotecan as Third-Line Therapy in Treating Patients With Metastatic Colorectal Cancer(PIMABI) | completed | Phase 2 | 65 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Sep 21, 2021 | clinicaltrials |
| NCT01006369 | Hydroxychloroquine, Capecitabine, Oxaliplatin, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 38 | Rutgers, The State University of New JerseyOTHER |
| 1 |
| Sep 21, 2021 |
| clinicaltrials |
| NCT03261947 | A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors | completed | Phase 2 | 101 | Millennium Pharmaceuticals, Inc.INDUSTRY | 2 | Sep 20, 2021 | clinicaltrials |
| NCT00007943 | Gemcitabine in Treating Patients With Advanced Colorectal Cancer | completed | Phase 2 | 15 | Wake Forest University Health SciencesOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT02414009 | Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients(CAPTEM) | completed | Phase 2 | 82 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT02992886 | Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly | completed | Phase 2 | 68 | Chinese Academy of Medical SciencesOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT03647839 | Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer(MODULATE) | completed | Phase 2 | 90 | Australasian Gastro-Intestinal Trials GroupNETWORK | 1 | Aug 27, 2021 | clinicaltrials |
| NCT03564912 | Prospective Study on the Efficacy and Safety of 2 Week or 3 Week Xelox Regimen for Adjuvant Chemotherapy in CRC | completed | Phase 1 / Phase 2 | 160 | Zhejiang UniversityOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT00040599 | Safety Study of 90Y-hMN14 to Treat Colorectal Cancer | completed | Phase 1 / Phase 2 | 72 | Gilead SciencesINDUSTRY | 5 | Aug 19, 2021 | clinicaltrials |
| NCT00041652 | Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer | completed | Phase 1 / Phase 2 | 30 | Gilead SciencesINDUSTRY | 1 | Aug 19, 2021 | clinicaltrials |
| NCT00574678 | Analyzing the Composition of Tears to Identify Cancer(ACT) | completed | Phase 1 / Phase 2 | 150 | University of ArkansasOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT02864849 | Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer | completed | Phase 2 | 81 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2021 | clinicaltrials |
| NCT00844233 | Study of Chemoembolisation Using Irinotecan Bead Prior to Surgery in Metastatic Colorectal Cancer(PARAGON-II) | completed | Phase 1 / Phase 2 | 40 | Boston Scientific CorporationINDUSTRY | 3 | Jul 21, 2021 | clinicaltrials |
| NCT02848079 | TAS-OX for Refractory Metastatic Colon Cancer | completed | Phase 1 / Phase 2 | 41 | Yale UniversityOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT00598975 | NKTR-102 in Combination With Cetuximab in Patients With Refractory Solid Tumors (Phase 2a) and Metastatic or Locally Advanced Colorectal Cancer (Phase 2b) | completed | Phase 2 | 18 | Nektar TherapeuticsINDUSTRY | 1 | Jul 12, 2021 | clinicaltrials |
| NCT00856375 | NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer | completed | Phase 2 | 83 | Nektar TherapeuticsINDUSTRY | 6 | Jul 12, 2021 | clinicaltrials |
| NCT02393755 | Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 42 | Roswell Park Cancer InstituteOTHER | 1 | Jul 8, 2021 | clinicaltrials |
| NCT00361842 | Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer | completed | Phase 2 | 65 | Jazz PharmaceuticalsINDUSTRY | 2 | Jul 2, 2021 | clinicaltrials |
| NCT01276379 | Study Evaluating Biomarkers in Patients With Colorectal Cancer and Native KRAS Treated With Chemotherapy + Cetuximab(POSIBA) | completed | Phase 2 | 221 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jul 2, 2021 | clinicaltrials |
| NCT01719380 | Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer | completed | Phase 2 | 156 | PfizerINDUSTRY | 12 | Jun 23, 2021 | clinicaltrials |
| NCT01902953 | Lymphoseek® as Lymphoid Tissue Targeting Agents in Colon Cancer(CNC) | completed | Phase 2 | 16 | Maimonides Medical CenterOTHER | 1 | Jun 23, 2021 | clinicaltrials |
| NCT03142516 | FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status(OPALO) | completed | Phase 2 | 20 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT01442935 | Chemotherapies Associated With Targeted Therapies on the Resection Rate of Hepatic Metastases | completed | Phase 2 | 256 | UNICANCEROTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT02227667 | Evaluate the Efficacy of MEDI4736 in Immunological Subsets of Advanced Colorectal Cancer | completed | Phase 2 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT00932438 | Drug-Eluting Bead, Irinotecan (DEBIRI) Therapy of Liver Metastasis From Colon Cancer With Systemic Fluorouracil, Oxaliplatin, Leucovorin and Bevacizumab(DEBIRI) | completed | Phase 1 / Phase 2 | 70 | University of LouisvilleOTHER | 2 | Jun 11, 2021 | clinicaltrials |
| NCT02181556 | Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 41 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Jun 7, 2021 | clinicaltrials |
| NCT03427268 | Clinical Trial of PM60184 in Advanced Colorectal Cancer After Standard Treatment | completed | Phase 2 | 32 | PharmaMarINDUSTRY | 3 | May 24, 2021 | clinicaltrials |
| NCT00511862 | TheraSphere for the Treatment of Liver Metastases | completed | Phase 2 | 151 | Boston Scientific CorporationINDUSTRY | 1 | May 13, 2021 | clinicaltrials |
| NCT02340949 | Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer(RIA) | completed | Phase 2 | 180 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 0 | May 3, 2021 | clinicaltrials |
| NCT01345526 | Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream | completed | Phase 2 | 124 | Universitätsmedizin MannheimOTHER | 2 | Apr 30, 2021 | clinicaltrials |
| NCT02217020 | Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer(FORTUNE) | completed | Phase 2 | 100 | Sun Yat-sen UniversityOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT01075048 | ARQ 197 in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 131 | Daiichi SankyoINDUSTRY | 5 | Apr 8, 2021 | clinicaltrials |
| NCT02811497 | Study of Azacitidine and Durvalumab in Advanced Solid Tumors(METADUR) | completed | Phase 2 | 28 | University Health Network, TorontoOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT02046174 | Open-Label Phase IIb Efficacy Trial of Cancer Macrobeads Compared to Best Supportive Care in Colorectal Cancer Patients | completed | Phase 2 | 70 | The Rogosin InstituteOTHER | 1 | Mar 24, 2021 | clinicaltrials |
| NCT04795180 | Pilot Randomized Evaluation of Butyrate Irrigation Before Ileostomy Closure on the Colonic Mucosa in Rectal Cancer Patients (BUTYCLO)(BUTYCLO) | completed | Phase 2 | 45 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT01037790 | Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer | completed | Phase 2 | 304 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 11, 2021 | clinicaltrials |
| NCT00066274 | Comparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | — | UNICANCEROTHER | 1 | Mar 2, 2021 | clinicaltrials |
| NCT02953782 | Study of Magrolimab (Hu5F9-G4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer | completed | Phase 1 / Phase 2 | 78 | Gilead SciencesINDUSTRY | 1 | Mar 1, 2021 | clinicaltrials |
| NCT00104689 | Capecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 60 | UNICANCEROTHER | 1 | Feb 21, 2021 | clinicaltrials |
| NCT01327612 | Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) | completed | Phase 2 | 12 | AmgenINDUSTRY | 3 | Feb 21, 2021 | clinicaltrials |
| NCT01927341 | Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors | completed | Phase 1 / Phase 2 | 53 | PfizerINDUSTRY | 7 | Feb 18, 2021 | clinicaltrials |
| NCT02641691 | Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum(NORMAL-R) | completed | Phase 2 | 20 | Washington University School of MedicineOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT00006050 | Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | completed | Phase 2 | — | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT00423696 | Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | completed | Phase 2 | 145 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02981524 | Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer | completed | Phase 2 | 17 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT01481545 | Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer(BRANCH) | completed | Phase 2 | 62 | National Cancer Institute, NaplesOTHER | 0 | Feb 3, 2021 | clinicaltrials |
| NCT03031444 | Perioperative Chemotherapy Plus Cetuximab Versus Chemotherapy Alone for High Risk Resectable Colorectal Liver Metastasis(PARECEC) | completed | Phase 2 / Phase 3 | 135 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT03443661 | Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer | completed | Phase 2 | 50 | Aiping ZhouUNKNOWN | 1 | Feb 1, 2021 | clinicaltrials |
| NCT00637091 | Efficacy Analysis of Cetuximab Plus Irinotecan in Patients With Wild-type KRAS Without Regard to Epidermal Growth Factor Receptor (EGFR) Expressions | completed | Phase 2 | 40 | Asan Medical CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT01298570 | Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer | completed | Phase 2 | 181 | UNC Lineberger Comprehensive Cancer CenterOTHER | 2 | Jan 6, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Sep 21, 2021source: clinicaltrials