Clinical trial · Interventional
Analyzing the Composition of Tears to Identify Cancer
ACT: Analyzing the Composition of Tears to Identify Cancer (Breast, Ovarian, Colon)
NCT00574678CI-TRIAL-00053097ACTcompletedPhase 1 / Phase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will further evaluate the use of protein identification or protein pattern (signature) found in tears. We hypothesize that differences exist between the protein profile in tear fluid from patients with versus without cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Benign Disease | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tear collection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- NO_INTERVENTION
- label
- 1
- interventionNames
- Other: Tear collection
Primary outcomes (1)
- measure
- This study will further evaluate the use of tumor markers (substances in body fluids that may be elevated as a consequence of certain diseases or conditions) in the diagnosis of breast and/or other cancers.
- timeFrame
- Collection of specimen and analysis with SELDI-MS
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female or male, 18-100 years old * Patients who present for a routine check-up * Patients who present for the evaluation of an abnormal exam or test (mammogram, ultrasound, MRI, PET, etc.) * May or may not have a mass present * Patients who present for the evaluation of a palpable lump or mass * Patients may be pre or post biopsy for a mass, as long as there is a portion of the mass remaining Exclusion Criteria: * Patient \< 18 y/o or \> 100 y/o * Concurrent eye infection or trauma * Active conjunctivitis * Abnormal production of tears (too much or too little)
References
Publications (0)
Data not yet available
No reference posted for this study.