Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06443671 | Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer(PKUCH-R09) | not yet recruiting | Phase 2 / Phase 3 | 132 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 5, 2024 | clinicaltrials |
| NCT05954078 | Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer | recruiting | Phase 3 | 340 | Fudan UniversityOTHER | 1 |
| May 20, 2024 |
| clinicaltrials |
| NCT01345175 | Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer | completed | Phase 3 | 69 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT03659448 | Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer | recruiting | Phase 3 | 300 | SurgimabINDUSTRY | 4 | Apr 24, 2024 | clinicaltrials |
| NCT05021263 | Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery? | completed | Phase 3 | 90 | Thomas Jefferson UniversityOTHER | 1 | Apr 9, 2024 | clinicaltrials |
| NCT06139926 | Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients With Colorectal Tumors | unknown | Phase 3 | 126 | First Affiliated Hospital of Chongqing Medical UniversityOTHER | 1 | Apr 9, 2024 | clinicaltrials |
| NCT06343116 | Nimotuzumab Combined With Trifluridine/Tipiracil in the Treatment of Refractory Metastatic Colorectal Cancer(NOTABLE-308) | not yet recruiting | Phase 3 | 420 | Biotech Pharmaceutical Co., Ltd.OTHER | 0 | Apr 2, 2024 | clinicaltrials |
| NCT03781154 | Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors | completed | Phase 3 | 31 | University of Colorado, DenverOTHER | 1 | Mar 20, 2024 | clinicaltrials |
| NCT03464305 | ASPIRIN Trial Belgium(ASPIRIN) | active not recruiting | Phase 3 | 148 | University Hospital, AntwerpOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT02301286 | A Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients(ASPIRIN) | active not recruiting | Phase 3 | 770 | Leiden UniversityOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT02102789 | A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis | unknown | Phase 3 | 142 | Yuhong LiOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT05726097 | Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure | completed | Phase 3 | 147 | Region SkaneOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT03413254 | Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases(COLOPEC-II) | active not recruiting | Phase 3 | 389 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Feb 23, 2024 | clinicaltrials |
| NCT00565708 | Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers(ASCOLT) | unknown | Phase 3 | 1,587 | National Cancer Centre, SingaporeOTHER | 10 | Feb 2, 2024 | clinicaltrials |
| NCT01515787 | PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery | unknown | Phase 2 / Phase 3 | 1,194 | Alliance for Clinical Trials in OncologyOTHER | 4 | Feb 2, 2024 | clinicaltrials |
| NCT05921942 | The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer | completed | Phase 3 | 70 | Ain Shams UniversityOTHER | 1 | Feb 2, 2024 | clinicaltrials |
| NCT06226857 | Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer(CRC01) | recruiting | Phase 3 | 355 | City Clinical Oncology Hospital No 1OTHER_GOV | 1 | Jan 29, 2024 | clinicaltrials |
| NCT06229041 | Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) | recruiting | Phase 3 | 472 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 29, 2024 | clinicaltrials |
| NCT03500874 | Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLM | terminated | Phase 3 | 92 | Sun Yat-sen UniversityOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT04338191 | mFOLFOXIRI Versus mFOLFOX6 as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer(FANTASTIC) | unknown | Phase 3 | 638 | Sun Yat-sen UniversityOTHER | 1 | Dec 27, 2023 | clinicaltrials |
| NCT05631041 | Effect of Silymarin in Metastatic Colorectal Cancer Patients | unknown | Phase 3 | 64 | Tanta UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT02519140 | Assessing How the Viscosity of Submucosal Gel Injections Helps With Endoscopic Mucosal Resections | withdrawn | Phase 3 | 0 | Antonios LikourezosOTHER | 1 | Dec 4, 2023 | clinicaltrials |
| NCT03414983 | An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread(CheckMate 9X8) | completed | Phase 2 / Phase 3 | 196 | Bristol-Myers SquibbINDUSTRY | 5 | Nov 18, 2023 | clinicaltrials |
| NCT06134388 | Sulfasalazine in Patients With Metastatic Colorectal Cancer | recruiting | Phase 3 | 50 | Tanta UniversityOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT02753127 | A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer(CanStem303C) | completed | Phase 3 | 1,253 | Sumitomo Pharma America, Inc.INDUSTRY | 16 | Nov 15, 2023 | clinicaltrials |
| NCT02394795 | Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC(PARADIGM) | completed | Phase 3 | 823 | TakedaINDUSTRY | 1 | Nov 1, 2023 | clinicaltrials |
| NCT03750786 | A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer(AGENT) | completed | Phase 3 | 490 | Isofol Medical ABINDUSTRY | 10 | Oct 26, 2023 | clinicaltrials |
| NCT06097416 | Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer | not yet recruiting | Phase 3 | 100 | St. James's Hospital, IrelandOTHER | 0 | Oct 25, 2023 | clinicaltrials |
| NCT02551237 | Neoadjuvant Treatment for Advanced Rectal Carcinoma(NACRE) | completed | Phase 3 | 103 | UNICANCEROTHER | 1 | Oct 13, 2023 | clinicaltrials |
| NCT05081687 | Brazilian Total Neoadjuvant Therapy Trial(BRAZIL-TNT) | unknown | Phase 3 | 150 | Hospital Israelita Albert EinsteinOTHER | 1 | Oct 11, 2023 | clinicaltrials |
| NCT06017583 | Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rectal Cancer | unknown | Phase 3 | 48 | Yong Zhang,MDOTHER | 1 | Oct 11, 2023 | clinicaltrials |
| NCT00958737 | Combination Chemotherapy for 3 Months or 6 Months in Treating Patients With Stage III Colon Cancer(IDEA) | unknown | Phase 3 | 2,000 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Sep 29, 2023 | clinicaltrials |
| NCT02614534 | Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal Carcinoma(HIPECT4) | unknown | Phase 3 | 200 | Maimónides Biomedical Research Institute of CórdobaOTHER | 1 | Sep 28, 2023 | clinicaltrials |
| NCT06049901 | Nitazoxanide in Patients With Metastatic Colorectal Cancer | unknown | Phase 3 | 60 | Tanta UniversityOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT01606098 | The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer(CAIRO4) | completed | Phase 3 | 206 | Dutch Colorectal Cancer GroupOTHER | 2 | Sep 13, 2023 | clinicaltrials |
| NCT01830621 | BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma | completed | Phase 3 | 282 | NCIC Clinical Trials GroupNETWORK | 3 | Aug 28, 2023 | clinicaltrials |
| NCT02031939 | Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer | unknown | Phase 3 | 556 | Sun Yat-sen UniversityOTHER | 1 | Aug 25, 2023 | clinicaltrials |
| NCT01011478 | Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery | terminated | Phase 3 | 406 | NSABP Foundation IncNETWORK | 2 | Aug 16, 2023 | clinicaltrials |
| NCT05984485 | The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer(TaLaR-02) | recruiting | Phase 3 | 766 | Sun Yat-sen UniversityOTHER | 1 | Aug 9, 2023 | clinicaltrials |
| NCT00079066 | Cetuximab + Best Supportive Care Compared With Best Supportive Care Alone in Metastatic Epidermal Growth Factor Receptor-Positive Colorectal Cancer | completed | Phase 3 | 572 | NCIC Clinical Trials GroupNETWORK | 2 | Aug 4, 2023 | clinicaltrials |
| NCT00640471 | Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Cancer | completed | Phase 3 | 750 | NCIC Clinical Trials GroupNETWORK | 1 | Aug 4, 2023 | clinicaltrials |
| NCT04262635 | Cetuximab Plus Capecitabine as Maintenance Treatment in RAS and BRAF wt Metastatic Colorectal Cancer(C-CLASSIC) | unknown | Phase 3 | 80 | Sun Yat-sen UniversityOTHER | 1 | Aug 2, 2023 | clinicaltrials |
| NCT03950154 | Study of Chemotherapy Combination With Autologous Cell Immunotherapy in the Recurrent and Metastatic Colorectal Cancer | unknown | Phase 3 | 198 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05970900 | Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST(PIRKER) | not yet recruiting | Phase 3 | 23 | Fujian Medical University Union HospitalOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT05948072 | Cetuximab+mFOLFOX6 VS. mFOLFOX6 Alone in RAS/BRAF Wild Type Patients With High-Risk Resectable CRLM | unknown | Phase 3 | 250 | Fudan UniversityOTHER | 1 | Jul 17, 2023 | clinicaltrials |
| NCT00303628 | Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer | terminated | Phase 3 | 355 | ECOG-ACRIN Cancer Research GroupNETWORK | 4 | Jul 6, 2023 | clinicaltrials |
| NCT00979680 | Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma(GRECCAR1) | completed | Phase 3 | 207 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Jun 29, 2023 | clinicaltrials |
| NCT00002525 | Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed | terminated | Phase 3 | 859 | ECOG-ACRIN Cancer Research GroupNETWORK | 1 | Jun 28, 2023 | clinicaltrials |
| NCT02969681 | Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer(Vitality) | completed | Phase 3 | 442 | Sun Yat-sen UniversityOTHER | 1 | Jun 27, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Jun 5, 2024source: clinicaltrials