Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04324476 | A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer | unknown | Phase 2 | 50 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Aug 30, 2021 | clinicaltrials |
| NCT04948034 | The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE) | unknown | Phase 2 | 68 | Fudan UniversityOTHER | 1 | Aug 27, 2021 | clinicaltrials |
| NCT04466254 | Efficacy and Safety Study of Combination of CPGJ602 and Chemotherapy, in First Line, With Wild KRAS/NRAS/BRAF in Metastatic Colorectal Cancer | unknown | Phase 2 | 75 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Aug 23, 2021 | clinicaltrials |
| NCT03727763 | Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT) | unknown | Phase 2 | 30 | Shanghai Changzheng HospitalOTHER | 1 | Aug 19, 2021 | clinicaltrials |
| NCT04989855 | Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score | unknown | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04988191 | Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer | unknown | Phase 1 / Phase 2 | 44 | Peking UniversityOTHER | 1 | Aug 3, 2021 | clinicaltrials |
| NCT04969029 | Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT04380012 | A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer | unknown | Phase 2 | 40 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 15, 2021 | clinicaltrials |
| NCT04293419 | Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer(DUREC) | unknown | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT04929652 | Surufatinib Combine With Immunotherapy and Chemotherapy for Second-line Treatment in Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 48 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT04664504 | A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk | unknown | Phase 2 | 150 | Jing Jin, M.D.UNKNOWN | 1 | Jun 8, 2021 | clinicaltrials |
| NCT04907864 | Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)(MIRACLE) | unknown | Phase 2 | 112 | Kil Yeon LeeOTHER | 1 | Jun 1, 2021 | clinicaltrials |
| NCT04535024 | The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer | unknown | Phase 2 | 60 | Fudan UniversityOTHER | 1 | May 11, 2021 | clinicaltrials |
| NCT02942706 | Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC | unknown | Phase 2 / Phase 3 | 200 | Ruijin HospitalOTHER | 0 | Apr 30, 2021 | clinicaltrials |
| NCT02167321 | Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision | unknown | Phase 2 | 90 | Yonsei UniversityOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT03484195 | Neoadjuvant FOLFOXIRI Chemotherapy in Patients With Locally Advanced Colon Cancer | unknown | Phase 2 | 30 | China Medical University, ChinaOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT03487939 | Neoadjuvant FOLFOXIRI Chemotherapy in Resectable Liver Metastasis of Colorectal Cancer | unknown | Phase 2 | 30 | China Medical University, ChinaOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT03484221 | Totally Neoadjuvant FOLFOXIRI + Short-course Radiation + XELOX in Patients With Locally Advanced Rectal Cancer | unknown | Phase 2 | 30 | China Medical University, ChinaOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT04838496 | Induction Chemotherapy for Locally Advanced Rectal Cancer(MEND-IT) | unknown | Phase 2 | 128 | Catharina Ziekenhuis EindhovenOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT04833036 | c-CetuIRI Versus Ersecond-line Irinotecan s-IRI-CetuIRI | unknown | Phase 2 | 120 | Fudan UniversityOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT04816045 | Neoadjuvant Electrochemotherapy for Colorectal Cancer - a Randomized Controlled Trial | unknown | Phase 1 / Phase 2 | 24 | Zealand University HospitalOTHER | 0 | Mar 25, 2021 | clinicaltrials |
| NCT04423965 | A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC | unknown | Phase 2 | 220 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer(CORT) | unknown | Phase 2 | 60 | Zhou FuxiangOTHER | 1 | Mar 17, 2021 | clinicaltrials |
| NCT03329664 | Autologous Killer Cell Therapy in Colon Cancer Patients | unknown | Phase 1 / Phase 2 | 20 | Sabz BiomedicalsINDUSTRY | 1 | Mar 15, 2021 | clinicaltrials |
| NCT04775862 | A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer. | unknown | Phase 2 | 60 | National Guard Health AffairsOTHER_GOV | 1 | Mar 1, 2021 | clinicaltrials |
| NCT04749381 | The Role of TCM on ERAS of Rectal Cancer Patients(RCT) | unknown | Phase 2 | 264 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 11, 2021 | clinicaltrials |
| NCT04737213 | SGM-101 in Colorectal Lung Metastases(SGM-CLM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT04508452 | A Phase II Prospective Trial of mXELOXIRI Reintroduction for mCRC | unknown | Phase 2 | 91 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04734249 | Second-line Surufatinib Combined With Chemotherapy in Advanced CRC | unknown | Phase 2 | 56 | Fujian Cancer HospitalOTHER_GOV | 0 | Feb 2, 2021 | clinicaltrials |
| NCT04695470 | Phase II Trial of Fruquintinib With Sintilimab in Treating Selected Refractory Metastatic Colorectal Cancer Patients | unknown | Phase 2 | 70 | Aiping ZhouUNKNOWN | 1 | Jan 7, 2021 | clinicaltrials |
| NCT04110093 | Regorafenib Plus PD-1 Inhibitor in Patients With Colorectal Cancer | unknown | Phase 1 / Phase 2 | 120 | Shanghai Changzheng HospitalOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT04668976 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | unknown | Phase 2 | 100 | Benaroya Research InstituteOTHER | 1 | Dec 21, 2020 | clinicaltrials |
| NCT04674696 | Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer(SHORT-ICAR) | unknown | Phase 2 | 54 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Dec 19, 2020 | clinicaltrials |
| NCT03985891 | The Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer(JSFOL) | unknown | Phase 1 / Phase 2 | 40 | Xiangya Hospital of Central South UniversityOTHER | 1 | Dec 17, 2020 | clinicaltrials |
| NCT04663763 | Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 | 40 | Zhejiang Cancer HospitalOTHER | 1 | Dec 11, 2020 | clinicaltrials |
| NCT04231552 | Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer | unknown | Phase 1 / Phase 2 | 30 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Nov 30, 2020 | clinicaltrials |
| NCT04264676 | Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer | unknown | Phase 2 | 294 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT04642924 | SGM-101 in Locally Advanced and Recurrent Rectal Cancer(SGM-LARRC) | unknown | Phase 2 / Phase 3 | 203 | Leiden University Medical CenterOTHER | 1 | Nov 24, 2020 | clinicaltrials |
| NCT03909724 | Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC)(SUNRISE-CRC) | unknown | Phase 2 / Phase 3 | 60 | Amsterdam UMC, location VUmcOTHER | 1 | Nov 13, 2020 | clinicaltrials |
| NCT04621370 | A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer(PRIME-RT) | unknown | Phase 2 | 48 | Liz-Anne LewsleyOTHER | 0 | Nov 9, 2020 | clinicaltrials |
| NCT03608046 | Avelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer(AVETUXIRI) | unknown | Phase 2 | 59 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT04593446 | Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery | unknown | Phase 2 | 414 | National Cancer Center, KoreaOTHER_GOV | 1 | Oct 20, 2020 | clinicaltrials |
| NCT04527068 | QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer(BEVTOR) | unknown | Phase 2 | 50 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Sep 17, 2020 | clinicaltrials |
| NCT04552093 | Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)(PUMP-IT) | unknown | Phase 2 / Phase 3 | 31 | The Netherlands Cancer InstituteOTHER | 1 | Sep 17, 2020 | clinicaltrials |
| NCT02226289 | Bevacizumab-containing Regimen for Metastatic Colorectal Cancer Failed to Cytotoxic Treatment(BATTLE) | unknown | Phase 2 | 46 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT04126655 | Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate | unknown | Phase 1 / Phase 2 | 30 | Vastra Gotaland RegionOTHER_GOV | 1 | Aug 27, 2020 | clinicaltrials |
| NCT04499586 | A Study of Radiotherapy Combined With Raltitrexed and Irinotecan in Metastatic or Locally Recurrent Colorectal Cancer | unknown | Phase 2 | 30 | Fudan UniversityOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT04337879 | A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 56 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jul 21, 2020 | clinicaltrials |
| NCT04476641 | A Study of DC-CIK Immunotherapy in the Treatment of Solid Tumors(DC-CIK) | unknown | Phase 2 | 686 | Sun Yat-sen UniversityOTHER | 1 | Jul 20, 2020 | clinicaltrials |
| NCT04475159 | Combined Neoadjuvant Systemic and PIPAC Therapy (NASPIT) for Patients With Colorectal Peritoneal Metastasis Eligible for CRS and HIPEC: A Prospective Phase II Trial | unknown | Phase 2 | 50 | Prof. Aviram NissanOTHER_GOV | 0 | Jul 17, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Aug 30, 2021source: clinicaltrials