Cancer Family
Intestinal Neoplasm
CI-CAN-00000209Explore in graph →
Non-malignant1,892 active trials21 approved drugs383 evidence items
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Cancer Family
CI-CAN-00000209Explore in graph →
Genomics
28 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
29 cases with simple somatic mutation data · 29 cases total · 2026-01-06 · mapped to Colon Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | APC |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 22 |
| 29 |
| 75.9% |
| cbioportal |
| 2 | TP53 | Ssm | 20 | 29 | 69% | cbioportal |
| 3 | KRAS | Ssm | 16 | 29 | 55.2% | cbioportal |
| 4 | TTN | Ssm | 11 | 29 | 37.9% | cbioportal |
| 5 | FLG | Ssm | 8 | 29 | 27.6% | cbioportal |
| 6 | SMAD4 | Ssm | 7 | 29 | 24.1% | cbioportal |
| 7 | HYDIN | Ssm | 6 | 29 | 20.7% | cbioportal |
| 11 | PIK3CA | Ssm | 5 | 29 | 17.2% | cbioportal |
| 9 | CSMD1 | Ssm | 5 | 29 | 17.2% | cbioportal |
| 8 | COL11A1 | Ssm | 5 | 29 | 17.2% | cbioportal |
| 10 | NEB | Ssm | 5 | 29 | 17.2% | cbioportal |
| 16 | DNAH3 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 19 | KMT2D | Ssm | 4 | 29 | 13.8% | cbioportal |
| 21 | PCLO | Ssm | 4 | 29 | 13.8% | cbioportal |
| 20 | PCDH17 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 12 | AHNAK2 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 18 | FRAS1 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 22 | PXDNL | Ssm | 4 | 29 | 13.8% | cbioportal |
| 15 | CYP19A1 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 13 | APOB | Ssm | 4 | 29 | 13.8% | cbioportal |
| 23 | SPATA31A3 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 24 | SYNE1 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 25 | TENM1 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 14 | CSMD2 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 17 | FBXW7 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 51 | NUP210L | Ssm | 3 | 29 | 10.3% | cbioportal |
| 52 | PAPPA2 | Ssm | 3 | 29 | 10.3% | cbioportal |
| 53 | PKDREJ | Ssm | 3 | 29 | 10.3% | cbioportal |
| 54 | PLCG2 | Ssm | 3 | 29 | 10.3% | cbioportal |
| 55 | PLXNB3 | Ssm | 3 | 29 | 10.3% | cbioportal |
Data updated 22 days agoSource updated 2026-01-06