Hematologic Malignancy
Indolent Systemic Mastocytosis
CI-CAN-00007849ISMExplore in graph →
HematologicNon-malignant3 active trials
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Hematologic Malignancy
CI-CAN-00007849ISMExplore in graph →
Clinical trials
15 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04910685 | (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis | recruiting | Phase 2 / Phase 3 | 534 | Blueprint Medicines CorporationINDUSTRY | 23 | Sep 23, 2026 | clinicaltrials |
| NCT07264959 | An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM) | recruiting | — | 150 | Blueprint Medicines CorporationINDUSTRY | 1 | Sep 4, 2026 | clinicaltrials |
| NCT06210698 | Angioedema Biomarker Research Study | recruiting | — | 600 | Foundation For Rare Disease ResearchOTHER | 1 | Aug 24, 2026 | clinicaltrials |
| NCT05186753 |
Data updated 4 days agoSource updated Sep 23, 2026source: clinicaltrials
| active not recruiting |
| Phase 2 |
| 237 |
| Cogent Biosciences, Inc.INDUSTRY |
| 15 |
| May 22, 2026 |
| clinicaltrials |
| NCT07255638 | A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany | recruiting | — | 80 | Blueprint Medicines CorporationINDUSTRY | 1 | Apr 20, 2026 | clinicaltrials |
| NCT03731260 | (PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis | active not recruiting | Phase 2 | 251 | Blueprint Medicines CorporationINDUSTRY | 13 | Sep 23, 2025 | clinicaltrials |
| NCT03770273 | Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic Mastocytosis | completed | Phase 2 | 21 | National Institute of Allergy and Infectious Diseases (NIAID)NIH | 1 | Dec 17, 2024 | clinicaltrials |
| NCT04655118 | Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis | unknown | Phase 2 | 121 | Telios Pharma, Inc.INDUSTRY | 13 | May 10, 2024 | clinicaltrials |
| NCT05923372 | Evaluation of the DALY on a Cohort of Patients With Indolent Systemic Mastocytosis(DALY-MAST) | unknown | — | 160 | University Hospital, ToulouseOTHER | 1 | Jul 12, 2023 | clinicaltrials |
| NCT04333108 | Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment | unknown | Phase 3 | 140 | AB ScienceINDUSTRY | 8 | May 6, 2023 | clinicaltrials |
| NCT00814073 | Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis(AB06006) | completed | Phase 3 | 135 | AB ScienceINDUSTRY | 2 | Dec 3, 2019 | clinicaltrials |
| NCT03632811 | Adaptation of the Questionnaire "Regarding Patient's Quality of Life With Mastocytosis" in the French Language(Mc_QoL) | completed | — | 30 | University Hospital, ToulouseOTHER | 1 | Jul 17, 2019 | clinicaltrials |
| NCT02808793 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK002 | completed | Phase 1 | 25 | Allakos Inc.INDUSTRY | 1 | Mar 13, 2019 | clinicaltrials |
| NCT02478957 | Treatment of Indolent Systemic Mastocytosis With PA101 | completed | Phase 2 | 41 | Patara PharmaINDUSTRY | 5 | Sep 29, 2016 | clinicaltrials |
| NCT01920204 | Midostaurin in Indolent Systemic Mastocytosis | unknown | Phase 2 | 20 | University Medical Center GroningenOTHER | 1 | Jan 19, 2015 | clinicaltrials |