Cancer Family
Hematopoietic and Lymphoid Cell Neoplasm
CI-CAN-00000023Explore in graph →
HematologicNon-malignant4,231 active trials98 approved drugs1,009 evidence items
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Cancer Family
CI-CAN-00000023Explore in graph →
Clinical trials
18,680 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01348919 | Delanzomib (CEP-18770) in Combination With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma | completed | Phase 1 / Phase 2 | 11 | Teva Branded Pharmaceutical Products R&D, Inc.INDUSTRY | 2 | Jun 28, 2023 | clinicaltrials |
| NCT03028103 | Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients | completed | Phase 1 | 32 | Epizyme, Inc. |
| 1 |
| Jun 26, 2023 |
| clinicaltrials |
| NCT00458653 | Vaccination With Dendritic Cell/Tumor Fusions With Autologous Stem Cell Transplants in Patients With Multiple Myeloma | completed | Phase 1 | 45 | Beth Israel Deaconess Medical CenterOTHER | 2 | Jun 22, 2023 | clinicaltrials |
| NCT01029366 | CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy | completed | Phase 1 | 26 | University of PennsylvaniaOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT01525394 | A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval | completed | Phase 1 | 52 | Eisai Inc.INDUSTRY | 1 | Jun 22, 2023 | clinicaltrials |
| NCT02135406 | CART-19 for Multiple Myeloma | completed | Phase 1 | 13 | University of PennsylvaniaOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT02141828 | A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Gene | completed | Phase 1 | 18 | Epizyme, Inc.INDUSTRY | 2 | Jun 18, 2023 | clinicaltrials |
| NCT02797964 | A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer | completed | Phase 1 / Phase 2 | 107 | Sierra Oncology LLC - a GSK companyINDUSTRY | 1 | Jun 18, 2023 | clinicaltrials |
| NCT00641030 | Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic Syndromes | completed | Phase 1 | 20 | City of Hope Medical CenterOTHER | 1 | Jun 15, 2023 | clinicaltrials |
| NCT02299518 | Selinexor and Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia | completed | Phase 1 | 23 | Alice MimsOTHER | 1 | Jun 15, 2023 | clinicaltrials |
| NCT02760485 | A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma | completed | Phase 1 / Phase 2 | 33 | Incyte CorporationINDUSTRY | 1 | Jun 15, 2023 | clinicaltrials |
| NCT03003546 | Nab-paclitaxel/Rituximab-coated Nanoparticle AR160 in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, LS1681 Trial | completed | Phase 1 | 9 | Mayo ClinicOTHER | 1 | Jun 15, 2023 | clinicaltrials |
| NCT04136756 | NKTR-255 in Relapsed/Refractory Multiple Myeloma & Non-Hodgkin Lymphoma | completed | Phase 1 | 30 | Nektar TherapeuticsINDUSTRY | 1 | Jun 15, 2023 | clinicaltrials |
| NCT00481091 | A Study of ABT-263 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia | completed | Phase 1 / Phase 2 | 60 | AbbVieINDUSTRY | 4 | Jun 13, 2023 | clinicaltrials |
| NCT03733951 | KN046 in Subjects With Advanced Solid Tumors and Lymphoma | completed | Phase 1 | 139 | Jiangsu Alphamab Biopharmaceuticals Co., LtdINDUSTRY | 1 | Jun 9, 2023 | clinicaltrials |
| NCT02280525 | Cord Blood Natural Killer (NK) Cells in Leukemia/Lymphoma | completed | Phase 1 | 8 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 7, 2023 | clinicaltrials |
| NCT04754100 | agenT-797 in Participants With Relapsed/Refractory Multiple Myeloma | completed | Phase 1 | 13 | MiNK TherapeuticsINDUSTRY | 1 | Jun 6, 2023 | clinicaltrials |
| NCT01860170 | Post-Transplant Bortezomib and High Dose Cyclophosphamide as Graft-Versus-Host Disease (GVHD) Prophylaxis | completed | Phase 1 / Phase 2 | 28 | Corewell Health WestOTHER | 1 | Jun 2, 2023 | clinicaltrials |
| NCT03311412 | Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas | completed | Phase 1 | 89 | Symphogen A/SINDUSTRY | 2 | May 30, 2023 | clinicaltrials |
| NCT03236857 | A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies | completed | Phase 1 | 143 | AbbVieINDUSTRY | 8 | May 22, 2023 | clinicaltrials |
| NCT02309580 | Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma | completed | Phase 1 | 14 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT03389035 | Transposon-manipulated Allogeneic CARCIK-CD19 Cells in Pediatric and Adult Patients With r/r ALL Post HSCT(CARCIK) | completed | Phase 1 / Phase 2 | 21 | Fondazione Matilde Tettamanti Menotti De Marchi OnlusOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT01925131 | S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia | completed | Phase 1 | 50 | SWOG Cancer Research NetworkNETWORK | 1 | May 3, 2023 | clinicaltrials |
| NCT04184869 | Extension Study for Patients Who Had Not Met Criteria for Discontinuation in Previous Sponsored Belinostat Trials | completed | Phase 1 | 8 | Acrotech Biopharma Inc.INDUSTRY | 1 | May 3, 2023 | clinicaltrials |
| NCT03841110 | FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors | completed | Phase 1 | 37 | Fate TherapeuticsINDUSTRY | 1 | May 1, 2023 | clinicaltrials |
| NCT02431988 | Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic Transplantation(COBALT) | completed | Phase 1 | 10 | University College, LondonOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT02751255 | Daratumumab in Combination With ATRA(DARA/ATRA) | completed | Phase 1 / Phase 2 | 60 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 28, 2023 | clinicaltrials |
| NCT03802955 | Study of ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma | completed | Phase 1 | 62 | Adagene (Suzhou) LimitedINDUSTRY | 1 | Apr 24, 2023 | clinicaltrials |
| NCT01191775 | A Study of PNT2258 in Patients With Advanced Solid Tumors | completed | Phase 1 | 22 | Sierra Oncology LLC - a GSK companyINDUSTRY | 1 | Apr 19, 2023 | clinicaltrials |
| NCT02659943 | T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies | completed | Phase 1 | 27 | National Cancer Institute (NCI)NIH | 1 | Apr 19, 2023 | clinicaltrials |
| NCT03242889 | A Study of Subcutaneous Delivery of JNJ-54767414 (Daratumumab) in Japanese Participants With Relapsed or Refractory Multiple Myeloma | completed | Phase 1 | 6 | Janssen Pharmaceutical K.K.INDUSTRY | 1 | Apr 14, 2023 | clinicaltrials |
| NCT03994913 | Clinical Trial to Evaluate CD19 CAR T (CT032) in Patients With Relapsed and/or Refractory Non-Hodgkin's B Cell Lymphoma | completed | Phase 1 / Phase 2 | 20 | CARsgen Therapeutics Co., Ltd.INDUSTRY | 1 | Apr 14, 2023 | clinicaltrials |
| NCT02891278 | Sertraline and Cytosine Arabinoside in Adults With Relapsed and Refractory AML | completed | Phase 1 | 6 | Columbia UniversityOTHER | 1 | Apr 12, 2023 | clinicaltrials |
| NCT01794520 | Study Evaluating ABT-199 in Participants With Relapsed or Refractory Multiple Myeloma | completed | Phase 1 / Phase 2 | 117 | AbbVieINDUSTRY | 4 | Apr 10, 2023 | clinicaltrials |
| NCT01040026 | Expanded Natural Killer (NK) Cells for Multiple Myeloma Study | completed | Phase 1 / Phase 2 | 10 | University Hospital, Basel, SwitzerlandOTHER | 1 | Apr 4, 2023 | clinicaltrials |
| NCT02185781 | Phase I Study of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL) | completed | Phase 1 | 6 | Gruppo Italiano Malattie EMatologiche dell'AdultoOTHER | 1 | Mar 30, 2023 | clinicaltrials |
| NCT02878785 | Decitabine and Talazoparib in Untreated AML and R/R AML(1565GCC) | completed | Phase 1 / Phase 2 | 25 | University of Maryland, BaltimoreOTHER | 1 | Mar 29, 2023 | clinicaltrials |
| NCT01393509 | The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies | completed | Phase 1 | 47 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 28, 2023 | clinicaltrials |
| NCT03886831 | A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies | completed | Phase 1 | 232 | Prelude TherapeuticsINDUSTRY | 1 | Mar 28, 2023 | clinicaltrials |
| NCT01575860 | Maintenance Lenalidomide in Lymphoma | completed | Phase 1 / Phase 2 | 8 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 27, 2023 | clinicaltrials |
| NCT02061761 | A Study to Evaluate the Safety, Tolerability, and Efficacy of Relatlimab in Relapsed or Refractory B-Cell Malignancies | completed | Phase 1 / Phase 2 | 106 | Bristol-Myers SquibbINDUSTRY | 2 | Mar 24, 2023 | clinicaltrials |
| NCT02561988 | (EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies | completed | Phase 1 | 86 | Blueprint Medicines CorporationINDUSTRY | 2 | Mar 17, 2023 | clinicaltrials |
| NCT02611063 | Evaluation of Fostamatinib in Patients With cGVHD After Allogeneic Stem Cell Transplant | completed | Phase 1 | 22 | Stefanie Sarantopoulos, MD, PhD.OTHER | 1 | Mar 17, 2023 | clinicaltrials |
| NCT04323657 | TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia | completed | Phase 1 / Phase 2 | 6 | TCR2 TherapeuticsINDUSTRY | 1 | Mar 16, 2023 | clinicaltrials |
| NCT00644189 | Oral Clofarabine for Relapsed/Refractory Non-Hodgkin Lymphoma | completed | Phase 1 / Phase 2 | 50 | Massachusetts General HospitalOTHER | 1 | Mar 15, 2023 | clinicaltrials |
| NCT01992653 | A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma | completed | Phase 1 / Phase 2 | 85 | Genentech, Inc.INDUSTRY | 2 | Mar 14, 2023 | clinicaltrials |
| NCT01572493 | Continuous Infusion of rhIL-15 for Adults With Advanced Cancer | completed | Phase 1 | 38 | National Cancer Institute (NCI)NIH | 1 | Mar 6, 2023 | clinicaltrials |
| NCT05720767 | HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study | completed | Phase 1 | 28 | HutchmedINDUSTRY | 1 | Mar 1, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Jun 28, 2023source: clinicaltrials