Cancer Family
Head and Neck Neoplasm
CI-CAN-00000021Explore in graph →
Non-malignant1,572 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000021Explore in graph →
Clinical trials
6,373 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04694846 | Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use | completed | N/A | 19 | Thomas Jefferson UniversityOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT05272917 | SOMESThesia and ALIMentation(SOMEST'ALIM) | completed | N/A | 72 | Hospices Civils de LyonOTHER | 1 | Sep 9, 2025 |
| NCT06771674 | Real-world Study of First Line Pembrolizumab- or Nivolumab-treated HPV-positive Recurrent/Metastatic Oropharyngeal Squamous Cell Carcinoma | completed | — | 662 | Hookipa Biotech GmbHINDUSTRY | 1 | Sep 9, 2025 | clinicaltrials |
| NCT04462471 | Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers | completed | Phase 1 | 8 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT05497947 | Evaluation of the French Translation of Swallowing (SOAL-VF) Patient Reported Outcomes (PRO) After Total PharyngoLaryngectomy(SOAL-VF) | completed | — | 225 | Centre Hospitalier de ValenceOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT00954226 | Phase Ib Study of Erlotinib Prior to Surgery in Patients With Head and Neck Cancer | completed | Phase 1 | 48 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT04879849 | A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers | completed | Phase 1 | 34 | TakedaINDUSTRY | 1 | Sep 4, 2025 | clinicaltrials |
| NCT03552965 | Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC | completed | N/A | 23 | University of ArkansasOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT04042298 | Microvascular Function in Patients Undergoing 5-Fluorouracil Chemotherapy | completed | — | 62 | Kansas State UniversityOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT04105543 | CLR 131 Combined With Radiation for Head and Neck Cancer | completed | Phase 1 | 12 | University of Wisconsin, MadisonOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT04356170 | Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma(TPFmORL) | completed | Phase 2 | 105 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT05323656 | A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN) | completed | Phase 2 | 55 | Calliditas Therapeutics Suisse SAINDUSTRY | 7 | Sep 2, 2025 | clinicaltrials |
| NCT06439745 | More Than 50% of Unifocal cN0 T1b/Small T2 Papillary Thyroid Carcinoma May Require Completion Thyroidectomy if Nodal Status is Evaluated(cN0PTC) | completed | — | 314 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Sep 2, 2025 | clinicaltrials |
| NCT02973997 | Lenvatinib and Pembrolizumab in Differentiated Thyroid Cancers (DTC) | completed | Phase 2 | 57 | Academic and Community Cancer Research UnitedOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT06272513 | Influencing Factors for Physical Activity in People With Head and Neck Cancer(ProAct-HNC) | completed | — | 20 | Kantonsspital Winterthur KSWOTHER | 1 | Aug 29, 2025 | clinicaltrials |
| NCT05828004 | The SHINE-MDT Randomized Controlled Trial | completed | N/A | 233 | West China HospitalOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT06638216 | Prospective Evaluation of Frailty in Patients With Head and Neck Tumors Before Curative Intended Therapy(PRE-KOVERI) | completed | N/A | 99 | Charite University, Berlin, GermanyOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT05022641 | Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy | completed | N/A | 160 | University of MichiganOTHER | 1 | Aug 27, 2025 | clinicaltrials |
| NCT06582849 | Enhanced Assistance During Radiotherapy for Unmet Essential Needs(EARN) | completed | N/A | 33 | Washington University School of MedicineOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT01723202 | Dabrafenib With or Without Trametinib in Treating Patients With Advanced Differentiated Thyroid Cancer | completed | Phase 2 | 53 | Bhavana KondaOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT07139054 | 68Ga-FAPI-46 PET/CT for the Prediction of Clinical Response to Neoadjuvant Therapy in Nasopharyngeal Carcinoma Patients | completed | — | 31 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT02079324 | Genetically Modified Mesenchymal Stem Cell Theraopeutic Against Head and Neck Cancer(GX-051) | completed | Phase 1 | 12 | Genexine, Inc.INDUSTRY | 1 | Aug 22, 2025 | clinicaltrials |
| NCT03489252 | Remote Activity Monitored by Fitbit Charge 3 in Investigating Daily Step and Sleep Data in Participants With Head and Neck Cancer Undergoing Radiation Therapy | completed | N/A | 41 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT05752669 | Oxidative Stress and Mitochondrial TERT in Papillary Thyroid Cancer.(TEMPEST) | completed | — | 100 | Istituto Auxologico ItalianoOTHER | 1 | Aug 21, 2025 | clinicaltrials |
| NCT05259696 | Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)(GLIMMER-01) | completed | Phase 1 / Phase 2 | 69 | Palleon Pharmaceuticals, Inc.INDUSTRY | 1 | Aug 20, 2025 | clinicaltrials |
| NCT05678348 | Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma | completed | Early Phase 1 | 22 | Washington University School of MedicineOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT01744587 | Epstein-Barr Virus Reactivation and the Effect of EGCG on Virus Reactivation in Remission Patients(NPC) | completed | N/A | 353 | National Health Research Institutes, TaiwanOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT02327078 | A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204) | completed | Phase 1 / Phase 2 | 307 | Incyte CorporationINDUSTRY | 2 | Aug 14, 2025 | clinicaltrials |
| NCT02475213 | Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory Cancer | completed | Phase 1 | 146 | MacroGenicsINDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT06273852 | A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors | completed | Early Phase 1 | 8 | Pure Biologics S.A.INDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT03623646 | Cisplatin or ImmunoTHerapy in Association With Definitive Radiotherapy in HPV-related oropharyngEal Squamous Cell Carcinoma: a Randomized Phase II Trial.(CITHARE) | completed | Phase 2 | 11 | Institut Claudius RegaudOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT04825834 | DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)(DELFI-L101) | completed | — | 2,992 | Delfi Diagnostics Inc.INDUSTRY | 2 | Aug 8, 2025 | clinicaltrials |
| NCT04952922 | Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer(FUNQOLR) | completed | — | 25 | Royal Marsden NHS Foundation TrustOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT05012098 | Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Aug 8, 2025 | clinicaltrials |
| NCT05022667 | Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy | completed | N/A | 114 | University of MichiganOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT02795195 | Trail Evaluating Carbon Ion Radiotherapy (3 GyE Per Fraction) for Locally Recurrent Nasopharyngeal Carcinoma | completed | Phase 1 / Phase 2 | 51 | Shanghai Proton and Heavy Ion CenterOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT05585034 | Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors | completed | Phase 1 | 60 | Xencor, Inc.INDUSTRY | 1 | Aug 7, 2025 | clinicaltrials |
| NCT04865731 | Dermaprazole Cream for Radiation Dermatitis in Head and Neck Cancer | completed | Phase 2 | 6 | The University of Texas Health Science Center at San AntonioOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT06535997 | Descriptive Cohort of French Patients Treated With Carbonetherapy Since October 2010 Outside PHRC-ETOILE(PRIMHADRON) | completed | — | 62 | Hospices Civils de LyonOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07107503 | 10 Years' Follow-up Results of Ultrasound-guided Radiofrequency Ablation Versus Surgery for Low-risk Papillary Thyroid Micro-carcinoma | completed | — | 757 | Yi MaoOTHER | 0 | Aug 6, 2025 | clinicaltrials |
| NCT02903914 | Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors | completed | Phase 1 | 260 | Incyte CorporationINDUSTRY | 4 | Aug 5, 2025 | clinicaltrials |
| NCT04197960 | Microwave Ablation and Surgical Resection for Micropapillary Thyroid Carcinoma | completed | N/A | 973 | Chinese PLA General HospitalOTHER | 1 | Aug 5, 2025 | clinicaltrials |
| NCT06048367 | Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor(CNSI-Fe(II)) | completed | Phase 1 | 19 | Sichuan Enray Pharmaceutical Sciences CompanyOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT00665392 | Cetuximab and Combination Chemotherapy in Patients With Stage III-IV Resectable Oropharynx Cancer(ECHO-07) | completed | Phase 2 | 42 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT00341497 | Biomarkers for Oral Cancer | completed | — | 80 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05156970 | Camrelizumab in Combination With Chemotherapy or Apatinib Mesylate as First-Line Treatment for R/M HNSCC | completed | Phase 2 | 81 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05517330 | Neoadjuvant Tislelizumab With Afatinib for Resectable Head and Neck Squamous Cell Carcinoma(neoCHANCE-1) | completed | Phase 2 | 23 | West China HospitalOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT05579782 | Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy | completed | N/A | 80 | Medical College of WisconsinOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT03795610 | IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma | completed | Phase 2 | 16 | Assuntina G. Sacco, MDOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT05581979 | PSMA-PET Imaging of Salivary Gland Tumours and Other Rare Cancers | completed | — | 4 | National Cancer Centre, SingaporeOTHER | 1 | Jul 25, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Sep 9, 2025source: clinicaltrials