Cancer Family
Head and Neck Neoplasm
CI-CAN-00000021Explore in graph →
Non-malignant1,574 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000021Explore in graph →
Clinical trials
6,377 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07131566 | Immune Response in Cervical Lymph Nodes of Patients With Head and Neck Cancer | recruiting | — | 500 | Lars Olaf CardellOTHER | 1 | Aug 20, 2025 | clinicaltrials |
| NCT06940505 | Telemedicine Follow-Up for Early Laryngeal Cancer: a Randomized Controlled Trial Comparing Care Close to Home Versus Standard of Care(Telemedicine) | recruiting | N/A | 140 | University Medical Center GroningenOTHER | 1 | Aug 19, 2025 |
| clinicaltrials |
| NCT07074392 | Assessing Spinal Accessory Nerve Recovery After Post-operative Electrical Stimulation(SpARES) | not yet recruiting | N/A | 38 | McMaster UniversityOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT07129525 | Health Oriented Protocol for Epidermal Radiodermatitis(HOPE) | not yet recruiting | — | 80 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Aug 19, 2025 | clinicaltrials |
| NCT07130851 | Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma | active not recruiting | N/A | 40 | Marketa BonaventurovaOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT06082167 | Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma(STELLAR-305) | active not recruiting | Phase 2 / Phase 3 | 600 | ExelixisINDUSTRY | 26 | Aug 17, 2025 | clinicaltrials |
| NCT07126457 | A Randomized Controlled Study on the Improvement of Medical Experience for Patients With Radiation-induced Oropharyngeal Mucositis Based on the RIS System of the Internet of Things | not yet recruiting | N/A | 110 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT04429542 | Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors | recruiting | Phase 1 | 292 | Bicara TherapeuticsINDUSTRY | 3 | Aug 15, 2025 | clinicaltrials |
| NCT05884983 | Screening Effect of Dual-energy CT Combined With Nasopharyngeal Endoscopy for Screening Nasopharyngeal Carcinoma | recruiting | — | 12,000 | Zhongshan People's Hospital, Guangdong, ChinaOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT06385132 | Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck Cancer(APPOINT) | recruiting | — | 207 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT07124065 | Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy | active not recruiting | — | 50 | Imperial College LondonOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT01985984 | Outcome Prediction in Head&Neck Cancer Patients After Radiotherapy(OutcomeH&N) | recruiting | — | 1,000 | Maastricht Radiation OncologyOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT02984410 | Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma(Best Of) | active not recruiting | N/A | 112 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 8 | Aug 14, 2025 | clinicaltrials |
| NCT05565313 | Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI(AI4rENE) | active not recruiting | — | 900 | Maastricht Radiation OncologyOTHER | 3 | Aug 14, 2025 | clinicaltrials |
| NCT06177301 | Tislelizumab Plus GX Versus Tislelizumab Plus GP in the Treatment of R/M NPC | recruiting | Phase 3 | 266 | Fudan UniversityOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT06492460 | 2 Courses of Concurrent Cisplatin Chemoradiotherapy After Surgery for High-risk Head and Neck Squamous Cell Carcinoma | recruiting | Phase 3 | 422 | Sun Yat-sen UniversityOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT06634706 | SCINTIX [BgRT} Using RMRS in Solid and Soft Tissue Tumors | not yet recruiting | N/A | 96 | RefleXion MedicalINDUSTRY | 0 | Aug 13, 2025 | clinicaltrials |
| NCT07116811 | Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients(SAF-NRVS) | not yet recruiting | Phase 3 | 364 | Beijing Tiantan HospitalOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT06700070 | A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors | recruiting | Early Phase 1 | 12 | Pure Biologics S.A.INDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT07026981 | [Ga-68]MTP220 PET for Biodistribution and Efficacy in Pancreatic Cancer and Head and Neck Cancers | not yet recruiting | Early Phase 1 | 12 | Qiubai LiOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT05222932 | Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1(AVENTIL) | active not recruiting | Phase 1 | 15 | TILT Biotherapeutics Ltd.INDUSTRY | 2 | Aug 7, 2025 | clinicaltrials |
| NCT05608876 | A Clinical Study to Investigate the Efficacy of Tigilanol Tiglate Directly in Head and Neck Cancer | active not recruiting | Phase 2 | 15 | QBiotics Group LimitedINDUSTRY | 2 | Aug 7, 2025 | clinicaltrials |
| NCT06688175 | IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal Carcinoma | enrolling by invitation | Phase 2 | 32 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT06970353 | Phase II Trial of Tunlametinib in NRAS-Mutant Advanced Thyroid Cancer | recruiting | Phase 2 | 40 | Fudan UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT07108517 | A Manualized Post-Traumatic Growth Intervention for People With Cancer in Greece - IC-Growth(IC-Growth) | recruiting | N/A | 180 | Centre for Research and Technology HellasOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT07110558 | Radiotherapy Omitting Prophylactic Neck Irradiation With Neoadjuvant and Adjuvant Toripalimab in Nasopharyngeal Carcinoma(PUPA) | not yet recruiting | Phase 2 | 59 | Sun Yat-sen UniversityOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT05947149 | HRQoL in Patients With Solid Tumors Treated With Hadrontherapy(HadroQoL) | recruiting | — | 180 | CNAO National Center of Oncological HadrontherapyOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07105592 | A Study of Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma | recruiting | Phase 1 / Phase 2 | 68 | Fudan UniversityOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT04675333 | Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04) | active not recruiting | Phase 2 | 172 | ALX Oncology Inc.INDUSTRY | 8 | Aug 3, 2025 | clinicaltrials |
| NCT05738603 | The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery. | recruiting | N/A | 206 | Jakub SzramaOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT05752604 | Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer(THY-CANC) | recruiting | — | 3,000 | Istituto Auxologico ItalianoOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT07072325 | Safety, Tolerability, PK, and Efficacy of CD-001 in Advanced Head & Neck Cancers | not yet recruiting | Phase 1 | 9 | West China HospitalOTHER | 0 | Aug 3, 2025 | clinicaltrials |
| NCT04675294 | Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03) | active not recruiting | Phase 2 | 189 | ALX Oncology Inc.INDUSTRY | 9 | Aug 1, 2025 | clinicaltrials |
| NCT06691776 | Feasibility of CBCT-Guided Online Adaptive Radiotherapy (FASCINATE)(FASCINATE) | recruiting | N/A | 100 | The Netherlands Cancer InstituteOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT07098819 | The eValuation of Sources of vIBRAtioN for Vibrational Shear Wave elasTography(VIBRANT) | not yet recruiting | — | 15 | Institute of Cancer Research, United KingdomOTHER | 0 | Aug 1, 2025 | clinicaltrials |
| NCT03649048 | Low-Dose Weekly vs High-Dose Cisplatin(RADIO) | recruiting | N/A | 100 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06307015 | De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)(DE-RADIATE) | recruiting | N/A | 25 | Royal North Shore HospitalOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT05894070 | The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer(VoiceDetect) | recruiting | — | 100 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT06236464 | Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas | recruiting | — | 170 | National Cancer Institute, NaplesOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT06805617 | A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers(I-MAC) | recruiting | Phase 2 | 35 | Glenn J. HannaOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT07090707 | PD-1 Inhibitor Therapy Versus Radiotherapy in MPR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy (HNC-SYSU-006) | not yet recruiting | Phase 2 | 50 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT07088484 | Watch-and-Wait After Immunochemotherapy in Locally Recurrent Nasopharyngeal Carcinoma | not yet recruiting | — | 50 | Fujian Cancer HospitalOTHER_GOV | 0 | Jul 28, 2025 | clinicaltrials |
| NCT06923826 | Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)(TROP2) | recruiting | Phase 2 | 32 | National University Hospital, SingaporeOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07085234 | Iparomlimab/Tuvorlimab (QL1706) and Modified TPF Regimen for Induction Therapy in LANPC | recruiting | Phase 2 | 30 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT07085988 | Effect of Nutritional Management on Patients With Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma | recruiting | Phase 2 | 109 | Jiangxi Provincial Cancer HospitalOTHER | 1 | Jul 25, 2025 | clinicaltrials |
| NCT05540899 | Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer | active not recruiting | Phase 1 | 14 | American College of RadiologyOTHER | 1 | Jul 24, 2025 | clinicaltrials |
| NCT07079410 | Neoadjuvant and Adjuvant Sintilimab Plus Cetuximab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma(OSCC) | not yet recruiting | Phase 2 | 50 | Shanghai Zhongshan HospitalOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT06935188 | Dalpicilib Plus Cetuximab Compared With Cetuximab Alone in HPV-negative, Anti-PD-1-resistant R/M HNSCC | recruiting | Phase 2 | 98 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT07072000 | Shrinking the Anterior Border of CTV2 for Nasopharyngeal Carcinoma to Reduce the Radiation of Nasal Cavity | not yet recruiting | Phase 3 | 550 | Hai-Qiang Mai,MD,PhDOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT07072143 | An International Study on Pediatric Patients With Rare Tumors.(PARTNER) | recruiting | — | 6,250 | Azienda Ospedaliera di PadovaOTHER | 1 | Jul 18, 2025 | clinicaltrials |
Data updated 24 days agoSource updated Aug 20, 2025source: clinicaltrials