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Clinical trials
341 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01275222 | Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors | completed | Phase 1 / Phase 2 | 117 | Novartis PharmaceuticalsINDUSTRY | 4 | Jun 25, 2021 | clinicaltrials |
| NCT02164240 | Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST(SURE) | completed | Phase 1 | 14 | Dana-Farber Cancer InstituteOTHER | 1 | Jun 14, 2021 |
| clinicaltrials |
| NCT03158103 | A Study of MEK162 (Binimetinib) in Combination With Pexidartinib in Patients With Advanced Gastrointestinal Stromal Tumor (GIST) | completed | Phase 1 | 3 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 30, 2021 | clinicaltrials |
| NCT01271712 | Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)(GRID) | completed | Phase 3 | 199 | BayerINDUSTRY | 17 | Jan 29, 2021 | clinicaltrials |
| NCT00135005 | Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST) | completed | Phase 1 | 59 | Novartis PharmaceuticalsINDUSTRY | 4 | Dec 8, 2020 | clinicaltrials |
| NCT01694277 | Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib | completed | Phase 3 | 258 | AB ScienceINDUSTRY | 4 | Dec 8, 2020 | clinicaltrials |
| NCT00028002 | Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor | completed | Phase 2 | 63 | National Cancer Institute (NCI)NIH | 1 | Oct 26, 2020 | clinicaltrials |
| NCT00510354 | Treatment of Patients With Everolimus and Imatinib Mesylate Who Have Progressive Gastro Intestinal Stromal Tumors (GIST) and Are Resistant to Imatinib Mesylate(Radix) | completed | Phase 4 | 28 | Novartis PharmaceuticalsINDUSTRY | 1 | Sep 10, 2020 | clinicaltrials |
| NCT01068769 | Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor | completed | Phase 2 | 34 | Suzanne George, MDOTHER | 1 | Aug 24, 2020 | clinicaltrials |
| NCT03880617 | Distress, Medication Adherence and Care Needs in Patients With CML and GIST Receiving Oral Targeted Therapy | completed | — | 297 | National Taiwan University HospitalOTHER | 1 | Aug 10, 2020 | clinicaltrials |
| NCT03426722 | L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors | completed | Phase 3 | 4 | Asan Medical CenterOTHER | 1 | Jul 13, 2020 | clinicaltrials |
| NCT04256226 | Clinical Outcome of Female Non-gastric Gastrointestinal Stromal Tumor | completed | — | 26 | Far Eastern Memorial HospitalOTHER | 1 | Jun 2, 2020 | clinicaltrials |
| NCT04343456 | Salvage Surgery for Patients With Metastatic GIST With Rego | completed | — | 41 | Chang Gung Memorial HospitalOTHER | 1 | Apr 14, 2020 | clinicaltrials |
| NCT00718211 | A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore | completed | — | — | National University Hospital, SingaporeOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02015065 | Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors | completed | Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02257541 | BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) | completed | Phase 1 / Phase 2 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT04269941 | Prognostic Factors Affecting Survival of Gastric GIST | completed | — | 34 | Université de SousseOTHER | 0 | Feb 17, 2020 | clinicaltrials |
| NCT01440959 | Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258 | completed | Phase 2 | 30 | Asan Medical CenterOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT01151852 | Rechallenge of Imatinib in GIST Having no Effective Treatment: RIGHT | completed | Phase 3 | 81 | Asan Medical CenterOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT02889328 | Phase II Study of Regorafenib Continuous Dosing of Regorafenib in Patients With GISTs | completed | Phase 2 | 25 | Asan Medical CenterOTHER | 1 | Jan 9, 2020 | clinicaltrials |
| NCT00278876 | Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation | completed | Phase 2 | 47 | Asan Medical CenterOTHER | 1 | Jan 7, 2020 | clinicaltrials |
| NCT00976612 | Nilotinib Pharmacokinetics (PK) in Gastrointestinal Stromal Tumor (GIST): Nilotinib PK | completed | — | 17 | Asan Medical CenterOTHER | 1 | Jan 7, 2020 | clinicaltrials |
| NCT02607332 | Paclitaxel in Patients With Metastatic or Advanced Gastrointestinal Stromal Tumors (GIST) After Failure to Imatinib and Sunitinib | completed | Phase 2 | 25 | Asan Medical CenterOTHER | 1 | Jan 7, 2020 | clinicaltrials |
| NCT03440515 | Management of Imatinib-associated Severe Skin Rash in Patients With Gastrointestinal Stromal Tumor | completed | Phase 2 | 29 | Asan Medical CenterOTHER | 0 | Jan 7, 2020 | clinicaltrials |
| NCT02574663 | TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors | completed | Phase 1 | 66 | TG Therapeutics, Inc.INDUSTRY | 1 | Oct 2, 2019 | clinicaltrials |
| NCT02931929 | MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT | completed | Phase 1 / Phase 2 | 9 | Medical University InnsbruckOTHER | 1 | Jul 19, 2019 | clinicaltrials |
| NCT02686944 | A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors(GIST) | completed | Phase 1 | 6 | MendusINDUSTRY | 1 | Jul 5, 2019 | clinicaltrials |
| NCT00428220 | A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study. | completed | N/A | 223 | PfizerINDUSTRY | 17 | Jun 27, 2019 | clinicaltrials |
| NCT00568750 | Dasatinib as First-Line Therapy in Treating Patients With Gastrointestinal Stromal Tumors | completed | Phase 2 | 47 | Swiss Cancer InstituteOTHER | 4 | Jun 17, 2019 | clinicaltrials |
| NCT01396148 | A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor | completed | Phase 2 | 6 | PfizerINDUSTRY | 3 | Mar 27, 2019 | clinicaltrials |
| NCT02606097 | Regorafenib in GIST With Secondary C-KIT Exon 17 Mutation | completed | Phase 2 | 19 | Chang Gung Memorial HospitalOTHER | 1 | Mar 21, 2019 | clinicaltrials |
| NCT00954655 | Study of Tumor Samples in Patients Undergoing Treatment for Gastrointestinal Stromal Tumors on Clinical Trial ACOSOG-Z9001 | completed | — | 1 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jan 30, 2019 | clinicaltrials |
| NCT00464620 | Trial of Dasatinib in Advanced Sarcomas | completed | Phase 2 | 366 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Nov 23, 2018 | clinicaltrials |
| NCT03722056 | Laparoscopic Management of Gastrointestinal Stromal Tumor of Stomach | completed | — | 42 | GEM Hospital & Research CenterOTHER | 0 | Oct 26, 2018 | clinicaltrials |
| NCT01560260 | Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors | completed | Phase 2 | 20 | National Cancer Institute (NCI)NIH | 1 | Sep 21, 2018 | clinicaltrials |
| NCT01154452 | Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma | completed | Phase 1 / Phase 2 | 78 | National Cancer Institute (NCI)NIH | 1 | Aug 15, 2018 | clinicaltrials |
| NCT01865565 | Surgery for Locally Unresectable Advanced GISTs Without Metastasis After Imatinib Therapy | completed | — | 51 | Chang Gung Memorial HospitalOTHER | 1 | Aug 9, 2018 | clinicaltrials |
| NCT02800330 | The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib(REGORA) | completed | Phase 4 | 31 | Erasmus Medical CenterOTHER | 1 | Aug 2, 2018 | clinicaltrials |
| NCT00103168 | Imatinib Mesylate or Observation Only in Treating Patients Who Have Undergone Surgery for Localized Gastrointestinal Stromal Tumor | completed | Phase 3 | 908 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 6 | Jul 9, 2018 | clinicaltrials |
| NCT01874665 | A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor(GIST) | completed | Phase 2 | 45 | Ariad PharmaceuticalsINDUSTRY | 1 | May 18, 2018 | clinicaltrials |
| NCT00867113 | Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST) | completed | Phase 2 | 91 | Novartis PharmaceuticalsINDUSTRY | 1 | Mar 14, 2018 | clinicaltrials |
| NCT00455559 | Ph II Study of Perifosine Plus Gleevec for Patients With GIST | completed | Phase 2 | 40 | AEterna ZentarisINDUSTRY | 0 | Feb 22, 2018 | clinicaltrials |
| NCT02884154 | Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors | completed | N/A | 39 | Pusan National University HospitalOTHER | 0 | Jan 23, 2018 | clinicaltrials |
| NCT01769248 | Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle(MUCIN) | completed | N/A | 140 | Northwestern UniversityOTHER | 1 | Jan 18, 2018 | clinicaltrials |
| NCT00979329 | Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST | completed | — | 100 | Radboud University Medical CenterOTHER | 1 | Nov 28, 2017 | clinicaltrials |
| NCT01265810 | Caphosol in Oral Mucositis Due to Targeted Therapy(COMTT) | completed | Phase 3 | 64 | Impaqtt FoundationOTHER | 1 | Nov 13, 2017 | clinicaltrials |
| NCT01770405 | Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract(US-nCLE) | completed | — | 40 | Mauna Kea TechnologiesINDUSTRY | 1 | Aug 29, 2017 | clinicaltrials |
| NCT03238820 | Robotic Resection for Patients With Gastric Gastrointestinal Stromal Tumors: a Single-center Study | completed | N/A | 50 | JIANG Zhi-WeiOTHER | 1 | Aug 3, 2017 | clinicaltrials |
| NCT00633295 | Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor | completed | Phase 2 | 9 | Novartis PharmaceuticalsINDUSTRY | 1 | Jun 22, 2017 | clinicaltrials |
| NCT00112463 | Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma | completed | Phase 2 | 40 | National Cancer Institute (NCI)NIH | 0 | Jun 14, 2017 | clinicaltrials |
Data updated 22 days agoSource updated Jun 25, 2021source: clinicaltrials