Gastric Soft Tissue Neoplasm — Variants & evidence

Gastric Soft Tissue Neoplasm — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

4 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–4 of 4 evidence items (4 on this page mapped to a descendant entity) · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
GLI1 Fusion4
(diagnostic)	Gastroblastoma	Diagnostic	C	Supports Positive	4	accepted	EID12080 This study identified a recurrent MALAT1::GLI1 fusion in 4 of 4 (100%) gastroblastomas from patients ranging in age from 9 to 56 years old. Initially, the fusion was identified using transcriptome seq… (full text at CIViC) PMID 37165307 · Hamada et al., 2023 · Open in CIViC	civic
〃	Gastroblastoma	Diagnostic	C	Supports Positive	4	accepted	EID12753 In this 2017 study the authors included four cases of gastroblastoma with control cases of histologic mimics. Gastroblastoma patients were aged 9, 27, 28 and 56 years. RNASeq identified a MALAT1::GLI1… (full text at CIViC) PMID 28731043 · Graham et al., 2017 · Open in CIViC	civic
〃	Gastroblastoma	Diagnostic	C	Supports Positive	2	accepted	EID12754 In this 2023 case study the authors investigate a tumour with biphasic morphology composed of epithelial and spindle cell components, diagnosed in a 29-year-old woman. RT-PCR analysis revealed that th… (full text at CIViC) PMID 36803776 · Sugimoto et al., 2023 · Open in CIViC	civic
〃	Gastroblastoma	Diagnostic	C	Supports Positive	2	accepted	EID12755 In this 2019 case study the authors investigate a gastric antral tumor with morphological, immunophenotypic and genotypic features consistent with gastroblastoma in a 79-year-old male. Molecular analy… (full text at CIViC) PMID 31287169 · Castri et al., 2019 · Open in CIViC	civic

Data updated 23 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.