Female Reproductive System Clear Cell Adenocarcinoma — Variants & evidence

Female Reproductive System Clear Cell Adenocarcinoma — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

2 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items (2 on this page mapped to a descendant entity) · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
ARID1A Loss1
(oncogenic)	Ovarian Clear Cell Adenocarcinoma	Oncogenic	B	Supports Oncogenicity	4	submitted	EID13135 Ovarian clear cell carcinoma is a relatively chemotherapy-refractory ovarian cancer subtype with a comparatively stable genome and a well-recognized association with endometriosis, but the somatic alt… (full text at CIViC) PMID 20942669 · Wiegand et al., 2010 · Open in CIViC	civic
PIK3CA Activation mutation1
(oncogenic)	Ovarian Clear Cell Adenocarcinoma	Oncogenic	B	Supports Oncogenicity	3	submitted	EID13136 Ovarian clear cell carcinoma is an aggressive and relatively chemotherapy-resistant form of ovarian cancer with a molecular landscape distinct from that of the more common epithelial subtypes. Earlier… (full text at CIViC) PMID 19349352 · Kuo et al., 2009 · Open in CIViC	civic

Data updated 22 minutes agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.