Cancer Family
Eye Neoplasm
CI-CAN-00000017Explore in graph →
Non-malignant86 active trials2 approved drugs19 evidence items
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Cancer Family
CI-CAN-00000017Explore in graph →
Clinical trials
463 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06227962 | Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors(RbNeuroQoL) | enrolling by invitation | — | 240 | Amsterdam University Medical CenterOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT05051384 | Superb Microvascular Intraocular Tumor Imaging Study (SMITIS)(SMITIS) | active not recruiting | N/A | 22 | Centre Hospitalier Universitaire de NiceOTHER | 1 |
| Dec 3, 2025 |
| clinicaltrials |
| NCT04681417 | Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome(RETINO 2018) | recruiting | Phase 2 / Phase 3 | 225 | Institut CurieOTHER | 1 | Nov 28, 2025 | clinicaltrials |
| NCT07136181 | Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma(NBM-BMX-UM) | recruiting | Phase 1 / Phase 2 | 36 | Novelwise Pharmaceutical CorporationINDUSTRY | 1 | Nov 28, 2025 | clinicaltrials |
| NCT01334008 | Study of Circulating Tumoral DNA in Metastatic Choroidal Melanoma | completed | N/A | 40 | Institut CurieOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT02866136 | Conservative Treatments of Retinoblastoma(RETINO2011) | active not recruiting | Phase 2 | 133 | Institut CurieOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT03618381 | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | active not recruiting | Phase 1 | 44 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06784648 | Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma | active not recruiting | Phase 1 / Phase 2 | 35 | BioInvent International ABINDUSTRY | 3 | Nov 19, 2025 | clinicaltrials |
| NCT05812027 | A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors | active not recruiting | — | 1,150 | TScan Therapeutics, Inc.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT01473004 | SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver | completed | Phase 2 | 48 | Thomas Jefferson UniversityOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT04935229 | Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma | terminated | Phase 1 | 67 | TriSalus Life Sciences, Inc.INDUSTRY | 1 | Oct 22, 2025 | clinicaltrials |
| NCT03713268 | Intraoperative OCT Guidance of Intraocular Surgery II(MIOCT) | recruiting | — | 262 | Duke UniversityOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT04344652 | Photoscreening for Retinoblastoma | withdrawn | N/A | 0 | Phoenix Children's HospitalOTHER | 0 | Sep 26, 2025 | clinicaltrials |
| NCT03712904 | Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma | terminated | Phase 2 | 3 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Sep 24, 2025 | clinicaltrials |
| NCT06805825 | A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit | recruiting | Phase 1 | 67 | Novelty Nobility, Inc.INDUSTRY | 1 | Sep 23, 2025 | clinicaltrials |
| NCT04812470 | Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases(HAITILS) | completed | Phase 1 | 8 | Vastra Gotaland RegionOTHER_GOV | 1 | Sep 22, 2025 | clinicaltrials |
| NCT02849145 | Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0)(ctDNA R0) | completed | N/A | 60 | Institut CurieOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT03932786 | Studying Health Outcomes After Treatment in Patients With Retinoblastoma(RIVERBOAT) | recruiting | — | 900 | Vanderbilt-Ingram Cancer CenterOTHER | 2 | Sep 19, 2025 | clinicaltrials |
| NCT04118062 | Communicating With Patients on Cancer Resistance to Treatment: the Development of a Communication Tool. (HECTOR) | completed | N/A | 128 | Institut CurieOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT07176130 | Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore | active not recruiting | — | 200 | Singapore National Eye CentreOTHER_GOV | 1 | Sep 16, 2025 | clinicaltrials |
| NCT03026998 | MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH)(DepiSCARRH) | active not recruiting | N/A | 88 | Institut CurieOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT05893654 | Melphalan Chemoreduction for Ocular Melanoma(MELCOM) | enrolling by invitation | Phase 1 / Phase 2 | 10 | Hospital das Clínicas de Ribeirão PretoOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT03809585 | Observational Study of Iris Tumors | recruiting | — | 100 | Oregon Health and Science UniversityOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT04283890 | PHP and Immunotherapy in Metastasized UM(CHOPIN) | active not recruiting | Phase 1 / Phase 2 | 83 | Leiden University Medical CenterOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT04728113 | Early Integration of Supportive Care for Metastatic Uveal Melanoma Patients (EarlyTogether)(EARLY TOGETHER) | completed | N/A | 162 | Institut CurieOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT00186888 | Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma | completed | Phase 3 | 107 | St. Jude Children's Research HospitalOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT04424719 | Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME)(SALOME) | recruiting | N/A | 700 | Institut CurieOTHER | 1 | Sep 3, 2025 | clinicaltrials |
| NCT05004025 | Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma | completed | Phase 1 | 10 | HonorHealth Research InstituteOTHER | 1 | Aug 15, 2025 | clinicaltrials |
| NCT05687474 | Baby Detect : Genomic Newborn Screening(BabyDetect) | completed | — | 6,824 | Centre Hospitalier Universitaire de LiegeOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT03964298 | Study of the Activity of PD-1 Inhibitors in Metastatic Uveal Melanoma(imMUno) | completed | — | 100 | Institut CurieOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT02874040 | Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser) | completed | N/A | 87 | Institut CurieOTHER | 1 | Aug 8, 2025 | clinicaltrials |
| NCT03611868 | A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 230 | Ascentage Pharma Group Inc.INDUSTRY | 2 | Aug 7, 2025 | clinicaltrials |
| NCT05841914 | Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma(DecodeVRL) | recruiting | — | 220 | Vinodh Kakkassery, MDOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT05315258 | Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma(TebeMRD) | active not recruiting | Phase 2 | 850 | University of OxfordOTHER | 1 | Jul 17, 2025 | clinicaltrials |
| NCT04720417 | Defactinib and VS-6766 for the Treatment of Patients With Metastatic Uveal Melanoma | terminated | Phase 2 | 13 | Thomas Jefferson UniversityOTHER | 1 | Jul 15, 2025 | clinicaltrials |
| NCT07063875 | Adding IL-2 to Tebentafusp to Eradicate Cancer Progression(SILVER) | recruiting | Phase 1 / Phase 2 | 8 | St Vincent's Hospital, SydneyOTHER | 1 | Jul 14, 2025 | clinicaltrials |
| NCT06424301 | Targeting NUDT21 siRNA Drugs for Patients With Refractory Retinoblastoma | recruiting | Early Phase 1 | 2 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | Jun 26, 2025 | clinicaltrials |
| NCT06970236 | Resistance Exercise in Patients With Ocular Melanoma(IHOPE) | recruiting | N/A | 40 | University of ValenciaOTHER | 1 | May 28, 2025 | clinicaltrials |
| NCT00661622 | Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF | completed | Phase 2 | 53 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT03922880 | Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma | completed | Phase 1 | 9 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT05502900 | Adjuvant Melatonin for Uveal Melanoma(AMUM) | recruiting | Phase 3 | 100 | Gustav StalhammarOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT06972602 | High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed | recruiting | Early Phase 1 | 10 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04342572 | Intra-arterial Chemotherapy for Retinoblastoma(IAC) | completed | Phase 1 | 5 | Washington University School of MedicineOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT00898755 | Collecting and Storing Tissue From Young Patients With Cancer | completed | — | 213 | Children's Oncology GroupNETWORK | 2 | May 2, 2025 | clinicaltrials |
| NCT01653080 | MRI in Diagnosing Solid Tumors of the Eye and Orbit | active not recruiting | N/A | 80 | University of CincinnatiOTHER | 1 | Apr 11, 2025 | clinicaltrials |
| NCT01355120 | THE IPI - Trial in Advanced Melanoma: Melanoma Patients With Advanced Disease(DeCOG) | completed | Phase 2 | 171 | Prof. Dr. med. Dirk SchadendorfOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT04463368 | Isolated Hepatic Perfusion in Combination With Ipilimumab and Nivolumab in Patients With Uveal Melanoma Metastases(SCANDIUM II) | completed | Phase 1 | 18 | Vastra Gotaland RegionOTHER_GOV | 1 | Mar 28, 2025 | clinicaltrials |
| NCT03172299 | Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated with Proton Therapy for a Large Choroidal Melanoma(PROTECT) | completed | Phase 3 | 57 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Mar 24, 2025 | clinicaltrials |
| NCT04802876 | Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors(ACROPOLI) | active not recruiting | Phase 2 | 184 | SOLTI Breast Cancer Research GroupOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT05576077 | A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors(STARLING) | terminated | Phase 1 | 31 | Turnstone Biologics, Corp.INDUSTRY | 2 | Mar 10, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Dec 4, 2025source: clinicaltrials